《功能性食品加工技术》课程改革的实践

通过对《功能性食品加工技术》课程教学内容、教学方法、考核方式等的全面改革实践,提出追踪行业技术前沿调整教学内容,模拟企业管理形式进行教学组织,贯穿教学全过程进行考核的教学模式是调动学生学习主动性,提高综合职业素质的有效途径。     

The relationship between parental bonding and peer victimization: examining child stress and hopelessness as mediators

The purpose of the current study was to investigate a two-stage model in which parent-related stress and hopelessness each served as mediators of the relationship between perceived parental bonding and South Korean adolescent peer victimization. This study also examined whether the mediating relationships differed by the gender of parents and adolescents. A casual chain with three links and four sets of variables were analyzed using structural equation modeling. Data were collected from 800 adolescents attending 10 middle schools in the Busan region of South Korea. Results indicated that both maternal and paternal parental bonding were negatively associated with stress, stress was positively associated with hopelessness, and hopelessness was positively associated with South Korean adolescent peer victimization. Most importantly, the significant negative associations between both maternal and paternal parental bonding and peer victimization were mediated by both stress and hopelessness. Furthermore, gender differences in these relationships existed for both parents and adolescents. Limitations and implications to practice were discussed.     

安陆方言中的"X得X"

讨论安陆方言中的“X得X”结构，分析这种结构所表示的语法意义以及产生这种结构的语法背景。     

Kinesin KIF4A is associated with chemotherapeutic drug resistance by regulating intracellular trafficking of lung resistance-related protein

Multidrug resistance (MDR) is the major impediment to cancer chemotherapy. The expression of lung resistance-related protein (LRP), a non-ATP-binding cassette (ABC) transporter, is high in tumor cells, resulting in their resistance to a variety of cytotoxic drugs. However, the function of LRP in tumor drug resistance is not yet explicit. Our previous studies had shown that Kinesin KIF4A was overexpressed in cisplatin (DDP)-resistant human lung adenocarcinoma cells (A549/DDP cells) compared with A549 cells. The expression of KIF4A in A549 or A549/DDP cells significantly affects cisplatin resistance but the detailed mechanisms remain unclear. Here, we performed co-immunoprecipitation experiments to show that the tail domain of KIF4A interacted with the N-terminal of LRP. Immunofluorescence images showed that both the ability of binding to LRP and the motility of KIF4A were essential for the dispersed cytoplasm distribution of LRP. Altogether, our results shed light on a potential mechanism in that motor protein KIF4A promotes drug resistance of lung adenocarcinoma cells through transporting LRP-based vaults along microtubules towards the cell membrane. Thus KIF4A might be a cisplatin resistance-associated protein and serves as a potential target for chemotherapeutic drug resistance in lung cancer.     

浅析惠州地区墙体材料的选择

本文通过对惠州地区建筑工程所用墙体材料的调查与分析, 并通过对烧结普通砖与新型墙体材料各项物理力学性能及经济指标的比较, 着重阐述了在实际工程当中惠州地区应广泛采用新型墙体材料的重要性, 以及大力推广墙体改革的必要性.     

谈谈投标的施工组织设计

通过对投标施工组织设计作用及特点的分析，阐述了投标施工组织设计在招投标过程中的重要性并指出了投标施工组织设计编制过程中一些经常易被忽视的重要问题。目的在于引导读者如何编制好投标施工组织设计文件。     

DNA甲基化异常与肿瘤发生的研究

DNA甲基化是真核生物DNA的正常内源性修饰方式 ,它由DNA甲基化转移酶催化发生。但DNA甲基化异常在肿瘤发生中却起着极为重要的作用 ,它主要表现为抑癌基因高甲基化所致的基因失活和原癌基因低甲基化所致的基因激活 ,引起与细胞增殖、分化相关基因表达异常 ,造成细胞恶变形成肿瘤。文章总结了DNA甲基化异常对肿瘤相关基因表达的影响 ,在肿瘤发生中的可能机制及针对高甲基化的治疗方案     

DISCRIMINATORY ORGANIZATIONAL CONTEXTS AND BLACK SCIENTISTS ON POSTSECONDARY FACULTIES

Severe underrepresentation of African-Americansamong postsecondary faculty is often linked toeducational pipeline supply problems,while institutional variations in demandfor black faculty labor and barriers to theirrecruitment and retention receive less empiricalattention. Using a nationally representative sample ofcollege faculty from a wide array of institutions andscience disciplines, this study investigates linksbetween internal organizational conditions and blackfaculty representation. Hypotheses derive from competingexplanations of the role of race in academicorganizations: institutionalized discrimination to protectdominant group privileges; statistical discriminationbased on expectations of racial group differences inacademic preparation; labor supply and politicalconstraints on black faculty recruitment. A multivariateanalysis examines organizational conditions that promoteor curb these dynamics and their relationship to blackappointments at different tenure levels. Results indicate that although the discipline-specificblack doctoral labor supply is a powerful constraint onthe representation of black faculty, selectiveorganizational contexts are substantial influences as well. Although we find little evidence thatinsulation from competition or segmented faculty labormarkets influence the racial composition of faculties,black faculty are more often found whereinstitutionalized discrimination may be checked by greaterformalization and black constituencies on campus.Consistent with statistical discrimination, blackfaculty are poorly represented at research-orientedinstitutions, even controlling for the scholarly reputationof doctoral credentials.     

金融体制改革中银行面临的问题及思考

在金融体制改革中，银行面临着自身的问题和整个金融环境的问题。因此，必须进一步深化商业银行改革和中央银行改革，使我国金融体制更有利于国家经济的发展。     

以“双创”为目标,探索产学合作人才培养机制

为了满足市场对人才的需求,提高人才培养质量,本文在当前创新创业应用型人才培养的大背景下,对产学合作人才培养机制的改革进行了有益的探索,提出了几点思路与方法,有利于培养学生的创新思维能力、工程应用能力和团队合作能力,更好地适应当前对创新创业应用型人才的需求。