结构方程模型和IRT等级反应模型在人格量表项目筛选中的对比研究

为比较结构方程模型和 IRT等级反应模型在人格量表项目筛选上的作用,以《中国大学生人格量表》的7229个实际测量数据为基础,针对因素二“爽直”分别以Lisrel8.70和Multilog7.03进行结构方程模型和等级反应模型的参数估计与拟合,比较两种方法的项目筛选结果.二者统计结果均认为项目5、6、7、8拟合度不佳,在结构方程模型上表现为因子负荷较低,整体拟合指数不理想;在等级反应模型上表现为区分度参数和位置参数不理想,相关项目的特征曲线和信息曲线形态较差.但结构方程模型倾向于项目6、8更差,而等级反应模型则倾向于项目5、6更差.结构方程模型和 IRT等级反应模型对人格量表项目的统计推断结果从总体上讲是一致的,但在个别项目上略有差异.二者各有优势,可以结合使用.     

Influence of casein phosphopeptide-amorphous calcium phosphate application,smear layer removal,and storage time on resin-dentin bonding

The aim of this study is to evaluate the influence of Tooth Mousse (TM) application, smear layer removal, and storage time on resin-dentin microtensile bond strength (μTBS). Dentin specimens were divided into two groups: (1) smear layer covered; (2) smear layer removed using 15% EDTA for 90 s. In each group, half the specimens were treated once with TM for 60 min. After bonding procedures using a two-step self-etching adhesive (Clearfil SE Bond (CSE); Kuraray Medical, Tokyo, Japan), an all-in-one adhesive (G-Bond (GB); GC Corp, Tokyo, Japan), and a total-etch adhesive (Adper Single Bond 2 (SB); 3M ESPE, St. Paul, MN, USA), the specimens were stored for 3 d or 6 months in deionized water at 37 °C, and μTBS was tested and analyzed. With the exception of SB (no TM application) and GB, the μTBS was significantly increased for CSE and SB using EDTA pre-conditioning and 3 d of storage (P≤0.001). Bond strength of GB decreased significantly when using EDTA (3 d storage, P<0.05). TM application only increased the μTBS of GB (no EDTA) and SB (with EDTA) after 3 d (P≤0.02). Comparing the adhesives after 3 d of storage, CSE exhibited the greatest μTBS values followed by GB and SB (P≤0.02). The factors of adhesive, EDTA, and TM did not show any significant impact on μTBS when specimens were stored for 6 months (P>0.05). The additional application of TM and EDTA for cavity preparation seems only to have a short-term effect, and no influence on μTBS of dentin bonds after a period of 6 months.     

Streptomycin inhibits electrophysiological changes induced by stretching of chronically infarcted rat hearts

Objective

To investigate stretch-induced electrophysiological changes in chronically infarcted hearts and the effect of streptomycin (SM) on these changes in vivo.

Methods

Sixty Wistar rats were divided randomly into four groups: a control group (n=15), an SM group (n=15), a myocardial infarction (MI) group (n=15), and an MI+SM group (n=15). Chronic MI was obtained by ligating the left anterior descending branch (LAD) of rat hearts for eight weeks. The in vivo blockade of stretch-activated ion channels (SACs) was achieved by intramuscular injection of SM (180 mg/(kg·d)) for seven days after operation. The hearts were stretched for 5 s by occlusion of the aortic arch. Suction electrodes were placed on the anterior wall of left ventricle to record the monophasic action potential (MAP). The effect of stretching was examined by assessing the 90% monophasic action potential duration (MAPD₉₀), premature ventricular beats (PVBs), and ventricular tachycardia (VT).

Results

The MAPD₉₀ decreased during stretching in both the control (from (50.27±5.61) ms to (46.27±4.51) ms, P<0.05) and MI groups (from (65.47±6.38) ms to (57.47±5.76 ms), P<0.01). SM inhibited the decrease in MAPD₉₀ during inflation ((46.27±4.51) ms vs. (49.53±3.52) ms, P<0.05 in normal hearts; (57.47±5.76) ms vs. (61.87±5.33) ms, P<0.05 in MI hearts). The occurrence of PVBs and VT in the MI group increased compared with that in the control group (PVB: 7.93±1.66 vs. 1.80±0.86, P<0.01; VT: 7 vs. 1, P<0.05). SM decreased the occurrence of PVBs in both normal and MI hearts (0.93±0.59 vs. 1.80±0.86 in normal hearts, P<0.05; 5.40±1.18 vs. 7.93±1.66 in MI hearts, P<0.01).

Conclusions

Stretch-induced MAPD₉₀ changes and arrhythmias were observed in chronically infarcted myocardium. The use of SM in vivo decreased the incidence of PVBs but not of VT. This suggests that SACs may be involved in mechanoelectric feedback (MEF), but that there might be other mechanisms involved in causing VT in chronic MI.     

辅助生殖技术学龄前单双胎子代的认知发展存在差异么?(英文)简

Objective： To explore whether there exist differences in cognitive development between singletons and twins born after in vitro fertilization （IVF） or intracytoplasmic sperm injection （ICSI）. Methods： A total of 566 children were recruited for the study, including 388 children （singletons, n=175; twins, n=213） born after IVF and 178 children （singletons, n=87; twins, n=91 ） born after ICSI. The cognitive development was assessed using the Chinese-Wechsler Intelligence Scale for Children （C-WISC）. Results： For all pre-term offspring, all the intelligence quotient （IQ） items between singletons and twins showed no significant differences no matter if they were born after IVF or ICSI. There was a significant difference in the cognitive development of IVF-conceived full-term singletons and twins. The twins born after IVF obtained significantly lower scores than the singletons in verbal IQ （containing information, picture ＆ vocabulary, arithmetic, picture completion, comprehension, and language）, performance IQ （containing maze, visual analysis, object assembly, and performance）, and full scale IQ （P〈0.05）. The cognitive development of full-term sin- gletons and twins born after ICSI did not show any significant differences. There was no significant difference between the parents of the singletons and twins in their characteristics where data were collected, including the age of the mothers, the current employment status, the educational backgrounds, and areas of residence. There were also no consistent differences in the duration of pregnancy, sex composition of the children, age, and height between sin- gletons and twins at the time of our study although there existed significant differences between the two groups in the sex composition of the full-term children born after ICSI （P〈0.05）. Conclusions： Compared to the full-term singletons born after IVF, the full-term twins have lower cognitive development. The cognitive development of full-term singletons and twins born after ICSI did not show any significant differences. For all pre-term offspring, singletons and twins born after IVF or ICSI, the results of the cognitive development showed no significant differences.     

阵发性房颤患者肺静脉隔离前后非肺静脉触发灶的诱发情况及随访研究(英文)

研究目的:观察阵发性房颤患者分别在肺静脉隔离前后联合使用三磷酸腺苷(ATP)+异丙(去甲)肾上腺素(ISP)对非肺静脉触发灶的诱发情况以及消融非肺静脉触发灶后的临床疗效。创新要点:发现肺静脉电学隔离前肺静脉在触发房颤方面起主要作用,环肺静脉隔离术显著降低了肺静脉的放电情况,却同时增强了肺静脉以外的部位触发房颤的能力。研究方法:选择从2010年4月至2011年1月在浙江大学附属邵逸夫医院首次行房颤射频消融术的药物治疗无效,发作时症状明显的80例阵发性房颤患者。所有的患者均于肺静脉隔离前后通过静脉给予ATP(20 mg)+ISP(20μg/min)诱发房颤。诱发出房颤的起始部分被标记和记录(诱发过程详见图2)。术后常规口服华法林抗凝不少于3个月,控制INR值2~3;术后3个月停用所有抗心律失常药物;术后1个月、3个月、6个月、1年、2年时及当病人有心悸等症状时通过24小时动态心电图对病人随访。重要结论:ATP+ISP可以有效诱发阵发性房颤患者的非肺静脉触发灶,特别是在环肺静脉隔离以后。术中对非肺静脉触发灶进行消融可能使病人获益,虽然在本研究中随访结果没有达到统计学上的显著差异。     

清代科举考试的题目成式

考试出题是考试活动的重要内容之一。出题方式与内容的变化,直接反映着考试制度文化变迁,是评价与衡量考试制度质量的重要指标。清代科举制度历经悠久的发展历程,其出题方式及考试内容趋于完善与稳定,成为彰显科举文化与精神的重要内容,也是考察清代科举考试制度改革与调整的重要视角。     

Pro/E在机械专业课程教学中的应用

在机械类专业课教学过程中使用Pro/E软件建立机械零件的三维模型有助于学生理解零件的结构.本文采用Pro/E对机械中凸轮机构进行运动仿真,实现量化凸轮机构的运动参数和特性,大大简化了计算过程;此外进行零件受力变形仿真,结果与计算基本吻合.建模和仿真结果表明,在机械类专业课程教学环节中使用Pro/E软件能够提高教学效率.     

卓越计划背景下高职“汽车检测与维修”技术专业改革与探索

汽车检测与维修技术专业是高职院校开设较多的专业,每年培养大量毕业生,但国内高技能维修人才仍有很大缺口,造成这种现象的重要原因之一是毕业生换行转业频繁.通过对南通地区汽车维修行业调研,分析学校培养和企业所需学生素质之间的差异,探究问题产生的深层次原因,提出基于卓越技师培养计划的汽检专业培养模式,强调学生职业素质和职业技能的双培养.     

电气类专业DSP原理及应用教学模式探索

DSP原理及应用是电气类工程专业本科开设的一门专业基础课程,旨在培养本科学生掌握DSP软件编程和硬件系统设计的能力。分析了DSP原理及应用课程的体系结构与教学要求,从理论教学与实践教学两个环节,对电气类专业DSP原理及应用课程的教学模式进行了探索。两年的教学实践效果良好。     

校企共建多样化网络实验室

网络实验室是培养高职院校网络专业技术技能人才的重要场所,通过校企共建网络实验室的实践,从多样化网络实验室建设需求、建设途径、校企共建框架、网络总体拓扑图设计及设备选择等方面,探讨校企共建功能、业务、设备厂商多样化的网络实验室。