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111.
Data play a crucial role in health research, education, and patient care. Initiatives such as Big Data to Knowledge (BD2K) and Precision Medicine point to the increasing focus and value of data use and reuse. As the universe of data continues to grow exponentially, health education needs to provide students with practical hands-on learning sessions that illustrate the multitude of uses for data and statistics. Giving students early exposure to data reuse provides a solid background for the more complex data they may gather later in their education. This column describes how librarians at a general academic library used data dashboards and Tableau in two library sessions to provide students with hands-on experience in data visualization and its role in decision-making.  相似文献   
112.
Much research is available that details student experiences of immigration and adaptation to receiving countries and schools, but few studies analyze the metaphors used by immigrant students (IS) when talking about the immigration experience, or offer a comparative lens through which to view identity negotiation in two very different contexts. The present paper aims to address these gaps by conducting a comparative linguistic analysis of 20 interviews conducted with IS at universities in South Africa and the United States in order to gain a greater understanding of immigration and the types of identity negotiation processes learners undergo in these very different countries. Findings reveal interesting similarities between metaphorical conceptions of immigration across different cultural contexts and a remarkable resilience in the use of adaptation strategies and identity development that leads to salient pedagogical implications for teachers of higher education who face increasingly international classrooms.  相似文献   
113.
Ceramic samples made with a mixture of 70% ball clay and 30% quartz sand were moulded and then fired at 900 °C in an electric kiln. Samples were then treated with different products and analyses and tests were performed to evaluate the physical changes induced by the application of these products and their effects on the quality of the ceramics. A petrographic study indicated that the ceramics were composed of quartz, small amounts of mullite and sanidine and traces of hematite. Mineral clays (i.e. kaolinite) disappeared during firing. Two consolidating products (Paraloid B72 and Tegovakon V) and one water repellent (Silo 111) were applied to samples by capillarity, and physical changes (colour, water flow, porosity and pore size distribution) were measured. Finally, we carried out salt crystallization tests in order to determine which product improved the quality of the ceramics. Treated samples registered a decrease in porosity and a general increase in pore size. The application of Silo 111 drastically reduced water absorption by immersion and by capillarity. This product was also responsible for a decrease in pore interconnection. Samples treated with Tegovakon V performed better in terms of their overall hydric behaviour. Silo 111 was the only product that did not modify the colour of samples when compared with untreated ones, and after accelerated aging tests, samples treated with this product hindered the absorption of saline solution into ceramic pores and prevented their decay. Paraloid B72 did not improve any of the properties of the ceramics.  相似文献   
114.
The sculptural polychromy in the Zhongshan Grottoes, sited in northwest China, has been investigated in terms of chemical composition of employed materials and pigments, state of conservation and painting technique. Raman analysis, Fourier-transform infrared analysis, analysis through energy-dispersive X-ray spectrometry coupled to scanning electron microscopy and pyrolysis coupled to gas chromatography and mass spectrometry were applied. Six analyzed samples showed silicates and kaolin as main components of the ground layers. Also lead white has been found in these layers. Minium, red-earth and mercury sulfide are the red pigments detected in the polychromy. A mixed use of malachite and atacamite has been detected in three green samples. Optical characteristics of atacamite and malachite found in the samples indicate a synthetic origin. The presence of a synthetic organic pigment such as phthalocyanine chlorinated pigment was also revealed. Ultramarine blue pigment, obtained by purification of lapis lazuli, has been detected in the blue sample. As for the binders used, fatty materials and siccative oil were found.  相似文献   
115.

Introduction

The study of cardiac response to strenuous and continuous exercise is crucial to understanding the physiology of endurance. N-terminal proB-type natriuretic peptide (NT-proBNP) is a potential marker for monitoring myocardial wall stress, and troponins (TnT and TnI) are widely used in the diagnosis of cardiac ischemia and infarction. Strenuous exercise may generate transitory ischemia, myocardial stress, and diastolic left ventricular dysfunction, inducing the increased production of both these biomarkers. We measured changes in NT-proBNP and TnT in elite cyclists during a 3-week stage race, a model of strenuous exercise.

Materials and methods:

The study population was 9 professional cyclists participating in the 2011 Giro d’Italia. Pre-analytical and analytical phases scrupulously followed official recommendations. Anthropometric data, net energy expenditure and cardiac indexes (rate, diastolic and systolic blood pressure) were recorded. Blood samples were drawn pre-race (day −1) and at days 12 and 22; NT-proBNP and highly sensitive-troponin (Hs-TnT) concentrations were assayed and corrected for plasma volume changes.

Results:

Body-mass index decreased and energy expenditure increased by 52% during the race. NT-proBNP concentrations increased [day −1: 23.52 ng/L (9.67–34.33); day 12: 63.46 ng/L (22.15–93.31); P = 0.039; day 22: 89.26 ng/L (34.66–129.78) vs. day −1; P < 0.001] and correlated with heart rate (r = −0.51; P = 0.006), systolic pressure (r = 0.39; P = 0.046) and energy expenditure (r = 0.70; P < 0.001). TnT concentrations did not vary, but a widened TnT amplitude distribution was observed.

Conclusions:

Increases in NT-proBNP correlated with higher energy expenditure over a 3-week cycling stage race, possibly indicating myocardial stress.  相似文献   
116.
IntroductionThe measurement of serum free light chain (FLC) represents a fundamental aspect on the assessment of patients with monoclonal gammopathies (MG). Different analytical methods for FLC have become available with the possibility to obtain different value with a substantial impact on the assessment of patients with MG. This study aimed to evaluate FLC results obtained with two different assays and how the difference value obtained can impact in the patient’s assessment.Materials and methodsNinety-three patient serum samples that underwent analysis for FLC with two different methods, Serum Freelite (The Binding Site, Birmingham, UK) and N-Latex FLC (Siemens, Marburg, Germany), were included in this retrospective study. Statistical analysis was performed to evaluate correlation, difference, and the grade of concordance between the results obtained with the two methods.ResultsSignificant statistical differences between the results obtained from the two methods were found (P < 0.05). A good correlation was found (0.99 for κ FLC, 0.95 for λ FLC, and 0.94 for the κ/λ ratio, respectively). We found a weighted kappa value of 0.65 for κ/λ ratio, 0.65 for λ FLC and 0.90 for κ FLC. A positive bias found with the Bland-Altman plot mirrors overestimation of κ FLC and κ/λ ratio with Freelite compared to N-Latex, whilst a negative bias underscores underestimation of λ FLC by Freelite compared to N-Latex.ConclusionAlthough in general the concordance between Freelite and N-Latex appears satisfactory, several discrepancies could be evidenced and consequently the two assays are not interchangeable.  相似文献   
117.
ABSTRACT

There is a strong relationship between low physical activity level and cardiovascular diseases (CVD). The popularity of football may be used to promote physical activity and previous evidence has shown it is effective to decrease the risk of CVD. However, the energy expenditure (EE) of recreational football is not well known but it is crucial to develop preventive health programmes.

Fifteen sedentary middle-aged male participants were involved (mean ± SDs; age 43.9 ± 3.1 years, weight 83.0 ± 13.6 kg, height 174.9 ± 6.8 cm). EE was estimated from the heart rate (HR)-VO2 relation during 1-h 5-a-side matches (futsal). Participants covered 3412 ± 381 m in 52 ± 2 min, at an average HR of 85 ± 2% of maximum HR. Estimated EE during a recreational futsal match was 634 ± 92 kcal. One futsal recreational match corresponds to about 50% of American College of Sport Medicine recommended physical activity quantity per week. Based on this estimation: once, twice and 3 sessions per week are equivalent to 50% (634 kcal), 100% (1268 kcal) and 150% (1902 kcal), respectively, of EE suggested in international guidelines. This EE estimation may have important implications for designing recreational football training protocols in health programmes and dose response studies.  相似文献   
118.
In this paper an identification method to estimate the parameters of a first-order plus time delay model is proposed. Such a method directly obtains these parameters using a new linear regression equation. No iterations in calculation are needed. Moreover, a simple true/false criterion to establish if the hypothesis on the process type is correct can be easily derived. The proposed method shows an acceptable robustness to disturbances and measurement noise as it is confirmed by several simulated experiments.  相似文献   
119.
Despite official government srt (in various jurisdictions around the world) for providing students with opportunities to construct their own knowledge within the context of formal schooling, school science systems continue to place greatest priority on teaching and learning of products of science (e.g., laws and theories), while compromising students’ opportunities to develop realistic conceptions about science and expertise for doing science. Based on qualitative data analyzed using constant comparative methods (based on constructivist grounded theory), we found this also to be the case – paradoxically – in a school belonging to the Canadian Coalition for Self-directed Learning (CCSDL). Schools in this coalition espouse, among various goals, enabling students to construct their own knowledge, in ways and directions suiting their individual needs, interests, perspectives, and abilities, in addition to gaining access to knowledge developed by society. The science department within the coalition school in this study experienced considerable difficulty realizing this goal, despite school-level administrative support for a concerted effort to reinvent itself along these lines. Factors that appeared to influence the science department’s efforts included those in each of Schwab’s (1969) educational "commonplaces;” that is, the curriculum, teachers, students, and the milieu surrounding teaching and learning. Further analysis suggests that results can be explained through reference to a Kuhnian (1962/1996) paradigm conflict – in which the school’s administrative and curricular committee and other members of the CCSDL were unsuccessful in convincing members of the science department (who, in turn, appeared to be supported by the provincial government, parents, and students) to make provisions for more student-directed, openended science inquiry. Assuming that student-led scientific inquiry continues to be an important curricular goal, efforts must continue to be made, therefore, to convince members of the mainstream paradigm that it is a worthy goal.  相似文献   
120.
Critical reflexivity has been acknowledged as fundamental in higher education. For facing complex situations in turbulent environments, students nowadays need not only to be taught technical knowledge, but also to be helped develop “relevant” learning for their future professional practice. In recent years, scholars have concentrated on what makes the internship experience a successful opportunity for the parties involved, and have also discussed the crucial role of a mentor/tutor in sustaining relevant and effective learning. However, the specific conditions that make tutorship successful in promoting critical reflexivity in such a boundary crossing experience need to be further explored. Aim of this paper is therefore to analyze what tutorship conditions sustain the development of critical reflexivity in internship. For this purpose, we will present the case study of an internship program run by one of the largest universities in northern Italy.  相似文献   
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