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21.
This paper studies the neural adaptive control design for robotic systems with uncertain dynamics under the existence of velocity constraints and input saturation. The control objective is achieved by choosing a control Lyapunov function using joint error variables that are restricted to linear growth and furthermore by introducing a secant type barrier Lyapunov function for constraining the joint rate variables. The former is exploited to bind the forward propagation of the position errors, and the latter is utilized to impose hard bounds on the velocity. Effective input saturation is expressed, and neural networks are employed to tackle the uncertainty problem in the system dynamics. Feasibility conditions are formulated, and the optimal design parameters are obtained by solving the constrained optimization problem. We prove that under the proposed method, semi-global uniform ultimate boundedness of the closed-loop system can be guaranteed. Tracking errors meanwhile converge to small neighborhoods of the origin, and violations of predefined velocity constraints are avoided. Finally, numerical simulations are performed to verify the effectiveness of the theoretical developments.  相似文献   
22.
Modern neuroscience increasingly relies on 3D models to study neural circuitry, nerve regeneration, and neural disease. Several different biofabrication approaches have been explored to create 3D neural tissue model structures. Among them, 3D bioprinting has shown to have great potential to emerge as a high-throughput/high precision biofabrication strategy that can address the growing need for 3D neural models. Here, we have reviewed the design principles for neural tissue engineering. The main challenge to adapt printing technologies for biofabrication of neural tissue models is the development of neural bioink, i.e., a biomaterial with printability and gelation properties and also suitable for neural tissue culture. This review shines light on a vast range of biomaterials as well as the fundamentals of 3D neural tissue printing. Also, advances in 3D bioprinting technologies are reviewed especially for bioprinted neural models. Finally, the techniques used to evaluate the fabricated 2D and 3D neural models are discussed and compared in terms of feasibility and functionality.  相似文献   
23.
In this paper a mathematical analysis is given, based on the modal technique, for transient calculations in nonuniform transmission lines. The untransposition and earth effects are included. A general formula for the voltage transform is deduced. Sequential pole switching is considered. The proposed method is applied to a typical 500 kV transmission line. The results obtained in this study are compared with similar results calculated by other investigators.  相似文献   
24.
This study investigated ESL teachers’ perceptions regarding the use of Computer Assisted Language Learning (CALL) in teaching reading to children. A random sample of 145 teachers participated in the study by completing a survey developed by the researchers. To explore the situation in depth, 16 teachers were later interviewed. Results indicated that the main purpose of using CALL with children is to help them develop reading strategies and increase their motivation. The most common strategies teachers reported using were computers to: enhance children's reading skills, support children's reading, listen to stories read aloud, recognize letter/sound relationships, and identify letters and beginning sounds of words. Teachers reported that CALL has some benefits, such as providing opportunities for active interaction and differentiated instruction. The main barriers of using CALL are the lack of resources and suitable software and hardware. The study ended with recommendations for further research and instructional improvements.  相似文献   
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26.
The present study aims to evaluate specific biomarkers involved in congenital heart disease (CHD), and whether there is a significant differences between the levels of these biomarkers in the cyanotic CHD (CCHD) and acyanotic CHD (ACHD). We prospectively measured tumor necrosis factor (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), vasoendothelial growth factor (VEGF), troponin T, creatin kinase MB (CKMB), and Caspase 3 levels in 120 consecutive children with CHD (60 cyanotic and 60 a cyanotic with age 1:4 years), and 30 healthy control children. Significant elevated levels of inflammatory markers; TNF-α, IL-6 and CRP was detected in CHD, with percentage increase in cyanotic than a cyanotic subjects as compared to the normal one. Apoptotic biomarker; caspase 3 showed also significant increases in CCHD than ACHD. In addition, tissue injury mechanisms included troponin T and CKMB, exhibited significant increase in cyanotic than a cyanotic CHD. The present results demonstrate also, significant enhancement in remodeling process (VEGF), in cyanotic than a cyanotic patients. Thus, it could be concluded that, the children with CCHD were shown to have elevated levels of inflammatory cytokines, caspase 3, troponin T, and CKMB as these biomarkers may implicated in cardiac functional status.  相似文献   
27.
Elevated free radical generation in inflamed joints and impaired antioxidant system has been implicated in rheumatoid arthritis (RA). Green tea extracts (GTE) have been shown to reduce inflammation in inflammatory arthritis murine model. This study investigates possible mechanisms by which vitamin C and GTE protect joints in RA rat model. This study included forty adult male rats that were divided into four groups (10 rats each); control group, collagen II induced RA group (CII), CII treated with vitamin C (CII + Vit C) and CII treated with GTE (CII + GTE) in physiology laboratory, Assiut University, Egypt. After 45 days of treatment, plasma levels of lipid peroxides (LPO), nitric oxide (NO), ceruloplasmin (CP), superoxide dismutase (SOD), uric acid (UA) and glutathione (GSH) were detected using colorimetric methods, PGE2 using ELISA and copper (Cu) and zinc (Zn) using spectrometer. In CII group, levels of LPO, NO, PGE2, UA, CP, Cu were higher while SOD, GSH, Zn were lower than controls. In groups treated with vitamin C and GTE, levels of SOD, GSH were increased while levels of LPO, NO, PGE2, Cu, CP were decreased compared with CII group. Levels of UA were decreased and Zn increased in GTE treated group compared with CII group. GTE treated group showed higher Zn and low Cu levels compared with vitamin C treated group. This study suggests proper GTE and vitamin C intake may effectively normalize the impaired oxidant/antioxidant system and delaying complication of RA.  相似文献   
28.
Despite the importance of personalization in information retrieval, there is a big lack of standard datasets and methodologies for evaluating personalized information retrieval (PIR) systems, due to the costly process of producing such datasets. Subsequently, a group of evaluation frameworks (EFs) have been proposed that use surrogates of the PIR evaluation problem, instead of addressing it directly, to make PIR evaluation more feasible. We call this group of EFs, indirect evaluation frameworks. Indirect frameworks are designed to be more flexible than the classic (direct) ones and much cheaper to be employed. However, since there are many different settings and methods for PIR, e.g., social-network-based vs. profile-based PIR, and each needs some special kind of data to do the personalization based on, not all the evaluation frameworks are applicable to all the PIR methods. In this paper, we first review and categorize the frameworks that have already been introduced for evaluating PIR. We further propose a novel indirect EF based on citation networks (called PERSON), which allows repeatable, large-scale, and low-cost PIR experiments. It is also more information-rich compared to the existing EFs and can be employed in many different scenarios. The fundamental idea behind PERSON is that in each document (paper) d, the cited documents are generally related to d from the perspective of d’s author(s). To investigate the effectiveness of the proposed EF, we use a large collection of scientific papers. We conduct several sets of experiments and demonstrate that PERSON is a reliable and valid EF. In the experiments, we show that PERSON is consistent with the traditional Cranfield-based evaluation in comparing non-personalized IR methods. In addition, we show that PERSON can correctly capture the improvements made by personalization. We also demonstrate that its results are highly correlated with those of another salient EF. Our experiments on some issues about the validity of PERSON also show its validity. It is also shown that PERSON is robust w.r.t. its parameter settings.  相似文献   
29.
Research in Science Education - The original version of this article unfortunately contained a mistake. The author would like to add the below text as acknowledgement.  相似文献   
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