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In persons with impaired glucose tolerance, serum glycated proteins (9.44±1.46μg hexose/mg protein) increased 1.69-fold (P<0.001) over control subjects compared to an increase of 1.95-fold in overt diabetics. However, correlations between serum glycated protein values and 2 h blood sugar values during the tolerance test (r=0.39) and between the former and graph area (r=0.30) were not strong. Glycated albumin (2.25 mol hexose/mol protein) and glycated haemoglobin (0.398±0.07 mol hexose/mol protein) in the study group also showed 1.67 and 1.24-fold increase respectively compared to controls. Fairly good correlations between glycated serum protein and glycated albumin (r=0.50) and glycated haemoglobin (r=0.45) were observed during this study. The data suggest that measurement of glycated proteins will be a useful index to detect impaired glucose tolerance.  相似文献   
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We studied the transition in predominant reading strategy from serial sublexical processing to more parallel lexical processing as a function of word familiarity in German children of Grades 2, 3, 4, and adults. High-frequency words, low-frequency words, and nonwords of differing length were embedded in sentences and presented in an eye-tracking paradigm. The size of the word length effect was used as an indicator of serial sublexical decoding. When controlling for the generally higher processing times in younger readers, the effect of length over reading development was not direct but modulated by familiarity: Length effects were comparable between items of differing familiarity for Grade 2, whereas from Grade 3, length effects increased with decreasing familiarity. These findings suggest that Grade 2 children apply serial sublexical decoding as a default reading strategy to most items, whereas reading by direct lexical access is increasingly dominant in more experienced readers.  相似文献   
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Rau EP 《Endeavour》2005,29(4):156-161
World War II became known as the "wizard war" because the cycles of developing countermeasures and counter-countermeasures to the weapons deployed by all sides drove rapid technological change. However, technological innovation was not the only contribution scientists made to the war effort. Through Operational Research (OR)--the scientific scrutiny of new weapons, their deployment and relative efficiency--scientists also influenced how warfare itself was conducted. This new scientific field emerged in the UK, where it helped to tighten the defense against the Luftwaffe. It quickly spread to other aspects of the military machine, improving both antisubmarine campaigns and bombing strategy. But although this analytical approach to warfare offered military commanders a factual basis on which to base difficult decisions and deal with tactical and strategic uncertainty, it was not without controversy. Indeed, several recommendations that came out of OR sparked disputes over the allocation of resources and strategic priorities.  相似文献   
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To learn content knowledge in science, technology, engineering, and math domains, students need to make connections among visual representations. This article considers two kinds of connection-making skills: (1) sense-making skills that allow students to verbally explain mappings among representations and (2) perceptual fluency in connection making that allows students to fast and effortlessly use perceptual features to make connections among representations. These different connection-making skills are acquired via different types of learning processes. Therefore, they require different types of instructional support: sense-making activities and fluency-building activities. Because separate lines of research have focused either on sense-making skills or on perceptual fluency, we know little about how these connection-making skills interact when students learn domain knowledge. This article describes two experiments that address this question in the context of undergraduate chemistry learning. In Experiment 1, 95 students were randomly assigned to four conditions that varied whether or not students received sense-making activities and fluency-building activities. In Experiment 2, 101 students were randomly assigned to five conditions that varied whether or not and in which sequence students received sense-making and fluency-building activities. Results show advantages for sense-making and fluency-building activities compared to the control condition only for students with high prior chemistry knowledge. These findings provide new insights into potential boundary conditions for the effectiveness of different types of instructional activities that support students in making connections among multiple visual representations.  相似文献   
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The current study compared eye fixation patterns during word and sentence processing in a consistent and an inconsistent alphabetic orthography. German and English children as well as adults matched on word reading ability read matched sentences while their eye fixation behavior was recorded. Results indicated that German children read in a more small-unit plodder-like style with more diligent first-pass reading and less rereading. In contrast, English children read in a more large-unit explorer-like style with a greater tendency to skip words, and more regressions. It is important that these cross-linguistic processing differences largely persisted in the adult readers. Orthographic consistency thus influences both local word recognition and global sentence processing in developing and skilled readers.  相似文献   
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Visual representations play a critical role in enhancing science, technology, engineering, and mathematics (STEM) learning. Educational psychology research shows that adding visual representations to text can enhance students’ learning of content knowledge, compared to text-only. But should students learn with a single type of visual representation or with multiple different types of visual representations? This article addresses this question from the perspective of the representation dilemma, namely that students often learn content they do not yet understand from representations they do not yet understand. To benefit from visual representations, students therefore need representational competencies, that is, knowledge about how visual representations depict information about the content. This article reviews literature on representational competencies involved in students’ learning of content knowledge. Building on this review, this article analyzes how the number of visual representations affects the role these representational competencies play during students’ learning of content knowledge. To this end, the article compares two common scenarios: text plus a single type of visual representations (T+SV) and text plus multiple types of visual representations (T+MV). The comparison yields seven hypotheses that describe under which conditions T+MV scenarios are more effective than T+SV scenarios. Finally, the article reviews empirical evidence for each hypothesis and discusses open questions about the representation dilemma.  相似文献   
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This study investigated variables contributing to older adults’ information technology acceptance through a survey, which was used to find factors explaining and predicting older adults’ information technology acceptance behaviors. Four factors, including needs satisfaction, perceived usability, support availability, and public acceptance, were found using factor analysis. According to older adults’ self-reported scores, the factors of needs satisfaction and support availability are relatively more important among the four factors. According to linear regression results, the factors of needs satisfaction and perceived usability are significantly related to use intention of information technology.  相似文献   
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