基于二模复杂网络的隐性知识发现方法研究——以潜在药物靶点挖掘为例

[目的/意义]通过构建二模复杂网络模型,揭示隐藏在海量文献中的隐性知识。[方法/过程]通过NetworkX复杂网络工具包,依据任意两个节点的共现关系构建二模复杂网络模型;对网络模型中节点的共现关系进行加权,计算网络的拓扑信息并进行AP聚类,提取节点间的直接关系;采用AUC方法对AA、JC、加权改进的wAA和wJC等4种链路预测算法进行评价,遴选出最合适的预测算法,并对复杂网络的隐性关系进行预测分析。[结果/结论]以潜在药物靶点挖掘为例进行的实证研究结果表明,wAA链路预测算法为最优的链路预测算法;二模复杂网络模型、指标和方法体系在美国化学文摘社数据库中的药物靶点挖掘中具有一定的有效性。下一步计划在其他数据库中或其他研究领域中进行尝试,以进一步验证该模型的通用性和有效性。     

一种改进的基于神经网络的入侵检测算法

径向基神经网络具有良好的分类特性,被广泛应用于入侵检测系统的研究中,然而RBF神经网络需要事先确定隐层神经元数目,并且容易陷入局部最优.利用遗传算法优化隐层神经元数目,并且基于粒子群思想优化隐层到输出层的权值,同时给出了详细的算法流程.经Lincoln实验室入侵检测系统数据评估集合测试,该智能算法的检测成功率大大提高,并且训练时间比较短,完全可以应用于入侵检测系统中.     

柳氮磺吡啶片近红外一致性检验方法研究

本文通过收集共32个批次的柳氮磺吡啶片样品,经实验室检验后,扫描其近红外光谱,结合实验室的检测结果,运用OPUS 5.0软件,建立柳氮磺吡啶片的一致性检验模型,并用新的样品来验证模型的准确性。本方法简便快捷,可以在不破坏包装的情况下准确鉴别柳氮磺吡啶片的真伪。     

跨国投资中政治风险的评价

政治风险是企业在跨国经营中最重要的风险之一,也是近几年导致我国许多企业海外投资失败的重要原因,因此,加强对跨国投资中政治风险的防范显得尤为迫切。分析了跨国投资中政治风险的影响因素,并从宏观和微观层面对跨国投资中政治风险的现有评估方法进行了阐述和总结,提出了适合我国企业对跨国投资特定项目进行政治风险评估的框架体系和评价方法。     

φ140mm无缝管机组的节能技术改造

介绍φ140mm无缝管机组生产节能工艺技术改造情况.分析原热穿冷拔工艺的能耗及废水排放,在原基础上改造为热轧工艺后,原煤消耗由原来的240.3kg/t降为201.6kg/t;电耗由原来的11 9.2Kwh/t降为92.4Kwh/t;节减了酸洗工序,废水排放由原来的203.2m3/d降为0m3/d,直接减少了石灰用量.每年可节约标煤3096t,节约电力21 5万Kwh,减少废水排放60960m3.节约硫酸、石灰消耗费用302.6万元.     

Extraterrestrial artificial photosynthetic materials for in-situ resource utilization

Aerospace milestones in human history, including returning to the moon and manned Martian missions, have been implemented in recent years. Space exploration has become one of the global common goals, and to ensure the survival and development of human beings in the extraterrestrial extreme environment has been becoming the basic ability and technology of manned space exploration. For the purpose of fulfilling the goal of extraterrestrial survival, researchers in Nanjing University and the China Academy of Space Technology proposed extraterrestrial artificial photosynthesis (EAP) technology. By simulating the natural photosynthesis of green plants on the Earth, EAP converts CO₂/H₂O into fuel and O₂ in an in-situ, accelerated and controllable manner by using waste CO₂ in the confined space of spacecraft, or abundant CO₂ resources in extraterrestrial celestial environments, e.g. Mars. Thus, the material loading of manned spacecraft can be greatly reduced to support affordable and sustainable deep space exploration. In this paper, EAP technology is compared with existing methods of converting CO₂/H₂O into fuel and O₂ in the aerospace field, especially the Sabatier method and Bosch reduction method. The research progress of possible EAP materials for in-situ utilization of extraterrestrial resources are also discussed in depth. Finally, this review lists the challenges that the EAP process may encounter, which need to be focused on for future implementation and application. We expect to deepen the understanding of artificial photosynthetic materials and technologies, and aim to strongly support the development of manned spaceflight.     

高原训练对提高青年女排运动员体能测试水平的分析

在全国青年女排高原集训期间,对集训前后两次助跑摸高、五次连续摸高、6 m×16次网下穿越移动、米字移动和800 m跑进行了对比分析.研究发现,高原训练对于助跑摸高和五次连续摸高的提高具有重要的意义;也可以促进6 m×16次网下穿越移动和米字移动的提高;800跑的成绩没有发现明显的提高;高原训练期间运动员的伤病情况明显增多.     

正六边孔的衍射场

为了研究正六边形小孔的衍射场,采用波前相因子判断法并考虑到孔径的影响对正六边形小孔的衍射场进行研究,得出正六边形小孔衍射场所含基元成份及衍射场的波前函数、像面上的振幅分布函数和光强分布函数,然后利用数值模拟的方法得出正六边形小孔在像面上的衍射图样;结果表明,在验证衍射理论的同时拓展了衍射的概念,能为深入理解光的衍射提供参考.     

松嫩平原菹草资源及其渔业利用

菹草是松嫩平原湖泊、水库等渔业水域较重要的资源植物。本文根据1984—1992年试验研究的部分成果,初步报道了该平原区渔业水域菹草资源现状和菹草型渔业水体生态系统特点,探讨了菹草的渔业经济价值,并提出菹草资源的渔业合理开发利用途径。     

Synergetic governing controller design for the hydraulic turbine governing system with complex conduit system

The hydraulic turbine governing system plays an indispensable role in maintaining the stability of electrical power system. In this paper, synergetic control theory is introduced to enhance the regulating ability of the hydraulic turbine governing system. For the purpose of describing the characteristics of objective system and deducing the synergetic control rule, a nonlinear mathematic model of a hydraulic turbine governing system with long tail race and two surge tanks is established. Furthermore, the nonlinear characteristic of the hydraulic turbine is described by six variable partial derivatives. For further investigation, the hydraulic turbine governing system is conducted to running under load condition when its coaxial generator connects to an infinite bus. Simulation experiments have been made under both load disturbance and three-phase short circuit fault conditions to compare the dynamic performances of proposed synergetic governing controller and classic PID controller. The results indicate that the proposed synergetic governing controller is an effective alternative in normal condition and a superior one in emergency. Moreover, the robustness of synergetic governing controller has also been discussed at the end of this paper.