商业银行中小企业融资服务的现状及对策

中小企业作为我国经济市场的重要组成部分,对我国市场经济的发展具有积极的促进作用.商业银行作为为中小企业提供融资服务的重要金融机构之一,对中小企业的经济发展起到举足轻重的作用,其融资服务质量直接影响到中小企业经济效益的提升情况.因此,本文将针对商业银行中小企业的融资服务现状进行探讨,并提出有效提升商业银行融资服务质量的对策,以供相关工作人员参考,进而保证商业银行能够为中小企业提供更为优质的融资服务,促进中小企业的可持续发展.     

预设与生成在教学活动中的重要性

新课程改革背景下成功、有效的学前教育教学活动,既离不开预设,也不能没有生成,预设和生成是辨证的对立统一体,两者是相互依存的.如果没有高质量的预设,就不可能有精彩的生成;反之,如果不重视生成,那么预设必然是僵化和缺乏生命活力的.因此,教师要用动态生成的观念来控制教学过程,预设应成为师生共同成长的经历过程,生成应当成为师生互动对话的支点.只有让预设与生成共舞,方能演绎精彩课堂.     

大学生考试焦虑的成因及调节方法

考试焦虑又称为考试恐怖,是指因考试压力引起的一种心理障碍。调查表明,不少大学生在期中、期末考试前会感到担心、焦虑,对考试存在不同程度的焦虑。本文对大学生考试焦虑的表现及其成因进行了分析研究,并提出应对考试焦虑的几种有效的调节方法。     

大学生网络生活状况的调查分析与对策研究

通过问卷抽样调查方式,了解在校大学生的网络行为,从网络意识等方面,分析他们的网络生活状况.提出丰富校园网络文化生活,提高大学生网络认知;深化计算机课程改革,培育大学生网络信息能力;拓宽思政教育平台,增强大学生网络信息鉴别能力;加强网络道德和法制教育,强化大学生网络规则意识等对策与建议,培养大学生网络素养,提升大学生网络生活品质.     

城市之间

每一次的旅行,无不是为了放松最好的借口,但也是让我们面对接下来那繁琐的一切。结束了终考,我选择了旅游,让我放松……     

Social information processing and coping strategies of shy/withdrawn and aggressive children: does friendship matter?

The primary objectives of this investigation were to examine the attributions, emotional reactions, and coping strategies of shy/withdrawn and aggressive girls and boys and to examine whether such social cognitions differ within the relationship context of friendship. Drawn from a sample of fifth and sixth graders (M age = 10.79 years; SD = .77), 78 shy/withdrawn, 76 aggressive, and 85 control children were presented with hypothetical social situations that first involved unfamiliar peers, and then a mutual good friend. Results revealed group and gender differences and similarities, depending on the relationship context. From our findings emerges a central message: friends' involvement during interpersonal challenges or stressors mitigates children's attributions, emotions, and coping responses.     

Edaravone protects PC12 cells from ischemic-like injury via attenuating the damage to mitochondria

Background： Edaravone had been validated to effectively protect against ischemic injuries. In this study, we investigated the protective effect of edaravone by observing the effects on anti-apoptosis, regulation of Bcl-2/Bax protein expression and recovering from damage to mitochondria after OGD （oxygen-glucose deprivation）-reperfusion. Methods： Viability of PC 12 cells which were injured at different time of OGD injury, was quantified by measuring MTT （2-（4,5-dimethylthia-zol-2-yl）-2,5-diphenyltetrazolium bromide） staining. In addition, PC 12 cells＇ viability was also quantified after their preincubation in different concentration of edaravone for 30 min followed by （OGD）. Furthermore, apoptotic population of PC 12 cells that reinsulted from OGD-reperfusion with or without preincubation with edaravone was determined by flow cytometer analysis, electron microscope and Hoechst/Pl staining. Finally, change of Bcl-2/Bax protein expression was detected by Western blot. Results： （1） The viability of PC12 cells decreased with time （1-12 h） after OGD. We regarded the model of OGD 2 h, then replacing DMEM （Dulbecco＇s Modified Eagle＇s Medium） for another 24 h as an OGD-reperfusion in this research. Furthermore, most PC 12 cells were in the state of apoptosis after OGD-reperfusion. （2） The viability of PC 12 cells preincubated with edaravone at high concentrations （1, 0.1, 0.01 μmol/L） increased significantly with edaravone protecting PC 12 cells from apoptosis after OGD-reperfusion injury. （3） Furthermore, edaravone attenuates the damage of OGD-reperfusion on mitochondria and regulated Bcl-2/Bax protein imbalance expression after OGD-reperfusion. Conclusion： Neuroprotective effects of edaravone on ischemic or other brain injuries may be partly mediated through inhibition of Bcl-2/Bax apoptotic pathways by recovering from the damage of mitochondria.     

Binding interactions of pefloxacin mesylate with bovine lactoferrin and human serum albumin

The binding of pefloxacin mesylate （PFLX） to bovine lactoferrin （BLf） and human serum albumin （HSA） in dilute aqueous solution was studied using fluorescence spectra and absorbance spectra. The binding constant K and the binding sites n were obtained by fluorescence quenching method. The binding distance r and energy-transfer efficiency E between pefloxacin mesylate and bovine lactoferrin as well as human serum albumin were also obtained according to the mechanism of Forster-type dipole-dipole nonradiative energy-transfer. The effects of pefloxacin mesylate on the conformations of bovine lactoferrin and human serum albumin were also analyzed using synchronous fluorescence spectroscopy.     

The impact of childhood sexual abuse in anorexia nervosa

OBJECTIVE: The aim of this study was to examine the impact of childhood sexual abuse (CSA) on clinical characteristics and premature termination of treatment in anorexia nervosa (AN). METHOD: The participants were 77 consecutive patients with AN admitted to an inpatient eating disorders unit. The patients were assessed in terms of eating disorder symptoms, general psychopathology, and CSA history at admission to hospital. RESULTS: Thirty-seven patients (48%) reported a history of CSA before the onset of the eating disorder. Individuals with a history of CSA reported significantly greater psychiatric comorbidity, including higher levels of depression and anxiety, lower self-esteem, more interpersonal problems, and more severe obsessive-compulsive symptoms. Patients with the binge-purge subtype of AN (AN-BP) were significantly more likely to report a history of CSA prior to the onset of the eating disorder as compared with patients with the restricting subtype (AN-R) of the illness (65% of the AN-BP patients vs. 37% of the AN-R patients; p<.02). Contrary to our predictions, abused patients were not significantly more likely to dropout of treatment overall. However, patients of the binge-purge subtype (AN-BP) with a history of CSA were significantly more likely to terminate treatment prematurely as compared with the other patients. CONCLUSIONS: Consistent with previous findings, the present results indicate that the prevalence of CSA is high among individuals seeking inpatient treatment for AN. A history of CSA was associated with greater psychiatric disturbance overall and a higher rate of dropout for patients of the binge-purge subtype.