微生物教学实验室生物安全的探索与研究

安全稳定是当今高校快速发展的根本保障,是建设和谐校园、平安校园的切入点和着力点。北京工业大学生命科学与生物工程学院微生物教学实验室,是伴随招收生物技术研究方向的本科生而诞生的专业基础教学实验室。由于教学和科研的密切关系,在病毒与药理研究室生物安全实践的基础上,从微生物教学实验室的特点等4个方面,对微生物教学实验室的生物安全问题进行有益的探索与研究,不仅提升师生的安全意识,同时有效促进实验教学的改革和创新。     

网络课程的内容进化机制设计与技术实现

当前我国网络课程建设与应用普遍存在以下问题:课程内容结构封闭和更新迟缓,教学形式具有单向传递性;课程内容与学习活动在应用上的分离,影响学生主体地位的发挥;不同教学学期衔接或课程内容在不同教师间共享时,教学过程中的生成性资源存在丢失的现象。因此,探讨如何根据网络课程内容进化理念,提供相应的环境与机制,从而促进学习内容、教师及学生三者在网络教学过程中的交互,并通过积聚大众智慧来促进课程内容的动态发展,对于提高网络课程教学质量具有重要意义。     

Enabling Mg metal anodes rechargeable in conventional electrolytes by fast ionic transport interphase

Rechargeable magnesium batteries have received extensive attention as the Mg anodes possess twice the volumetric capacity of their lithium counterparts and are dendrite-free. However, Mg anodes suffer from surface passivation film in most glyme-based conventional electrolytes, leading to irreversible plating/stripping behavior of Mg. Here we report a facile and safe method to obtain a modified Mg metal anode with a Sn-based artificial layer via ion-exchange and alloying reactions. In the artificial coating layer, Mg₂Sn alloy composites offer a channel for fast ion transport and insulating MgCl₂/SnCl₂ bestows the necessary potential gradient to prevent deposition on the surface. Significant improved ion conductivity of the solid electrolyte interfaces and decreased overpotential of Mg symmetric cells in Mg(TFSI)₂/DME electrolyte are obtained. The coated Mg anodes can sustain a stable plating/stripping process over 4000 cycles at a high current density of 6 mA cm⁻². This finding provides an avenue to facilitate fast ion diffusion kinetics of Mg metal anodes in conventional electrolytes.     

太极拳桩功对改善骨盆前倾的作用

在现代信息化生活中,网络已全面侵入我们的日常生活,儿童少年乃至老年人都在使用手机、电脑。由于长期不良的久坐姿势会造成人体形态的改变。其中在青年人中骨盆前倾尤为常见。本文主要运用文献法、问卷调查法从造成骨盆前倾的原因及对人体的危害上进行阐述,引起人们重视,继而提出卷腹运动、太极拳桩功对骨盆前倾的改善方法。     

一次性塑料快餐盒盖成型工艺分析及逆向设计

采用逆向思维方法,详细分析了一次性快餐盒盖的成型工艺,并对其结构进行改进设计。为那些以实物为制造基础的产品的设计提供了借鉴,在缩短产品开发周期,提高经济效益方面,起着重要作用。     

Injectable hybrid inorganic nanoscaffold as rapid stem cell assembly template for cartilage repair

Cartilage injuries are often devastating and most cannot be cured because of the intrinsically low regenerative capacity of cartilage tissues. Although stem-cell therapy has shown enormous potential for cartilage repair, the therapeutic outcome has been restricted by low survival rates and poor chondrocyte differentiation in vivo. Here, we report an injectable hybrid inorganic (IHI) nanoscaffold that facilitates fast assembly, enhances survival and regulates chondrogenic differentiation of stem cells. IHI nanoscaffolds that strongly bind to extracellular matrix (ECM) proteins assemble stem cells through synergistic 3D cell–cell and cell–matrix interactions, creating a favorable physical microenvironment for stem-cell survival and differentiation in vitro and in vivo. Additionally, chondrogenic factors can be loaded into nanoscaffolds with a high capacity, which allows deep, homogenous drug delivery into assembled 3D stem-cell-derived tissues for effective control over the soluble microenvironment of stem cells. The developed IHI nanoscaffolds that assemble with stem cells are injectable. They also scavenge reactive oxygen species and timely biodegrade for proper integration into injured cartilage tissues. Implantation of stem-cell-assembled IHI nanoscaffolds into injured cartilage results in accelerated tissue regeneration and functional recovery. By establishing our IHI nanoscaffold-templated 3D stem-cell assembly method, we provide a promising approach to better overcoming the inhibitory microenvironment associated with cartilage injuries and to advance current stem-cell-based tissue engineering.     

MPI下矩阵相乘的实现与分析

随着多核处理器及并行计算机的发展,并行程序设计在高性能计算及进程通信等领域得到更广泛的应用。而MPI(Message Passing Interface消息传递接口)作为目前最重要的并行编程工具,提供了丰富的消息传递库函数,极大方便了并行算法的实现。本文首先介绍并行计算及MPI的基本内容,然后在MPI并行计算环境下实现了一种n×n阶矩阵相乘的并行算法,并与传统的串行算法进行了性能方面的分析和比较。     

研究所文献资源保障体系建设——以新疆理化所为例

印本资源和电子资源共同构成研究所图书馆的信息资源体系,研究所图书馆在有限经费的情况下,要把握科研的需求、凝练采购目标、组织公开获取资源、共建共享机制下,充分利用第三方资源,构建文献资源保障体系。     

变革型领导行为、战略柔性与企业绩效

领导行为与企业绩效关系的研究一直倍受学术界关注。本研究将战略柔性(资源柔性和能力柔性)作为中介变量,研究动态环境下变革型领导行为对企业绩效的影响并提出研究假设,通过对北京、上海、广东等地区208家上市企业高管的问卷调查及相对应的企业年报获取研究数据并进行数据检验,验证研究假设。研究结果发现,资源柔性和能力柔性在变革型领导行为与企业绩效的关系中具有完全中介作用;环境动态性显著调节变革型领导行为与资源柔性和能力柔性的关系,但对战略柔性与企业绩效的关系无调节作用。本研究的结果说明,动态环境下变革型领导在推动企业变革的过程,要重视战略柔性的作用,引导企业通过转型来适应动态环境,提升企业绩效。     

(0608)超强台风“桑美”的特点及成因分析

2006年第8号台风"桑美"(0608,SAOMAI)是1949年以来登陆我国大陆最强的台风,登陆时中心附近最大风力达到17级(60m·s-1),最低气压为920hPa,利用常规探测资料、地面资料、风云2C红外云图及北京T213资料,对其观测事实进行分析探讨,结果发现,"桑美"台风具有强度强、移速快、结构紧密,"个头"小、风速大、雨势猛、灾害重等特点,这些特点与大气环流的演变、影响台风的天气系统、相关物理量的分布、"桑美"本身的结构及其结构变化等有着十分密切的关系。对它进行研究具有重要的社会意义和经济意义。