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21.
When students reason during school science, they often refer to conceptions that are derived from out-of-school experiences and are poor proxies for science orthodoxy. However, for some areas of science, these conceptions represent only a proportion of students' full conceptual knowledge, for tacit understanding exists that is superior to the understanding displayed when reasoning. Noting that tacit understanding is engaged when events are judged as natural or non-natural, the paper is concerned with software that: (a) requires direction and speed of falling objects to be predicted, i.e. a typical science reasoning task that engages conceptual knowledge; (b) presents simulations of predicted motion in the expectation that its naturalness or non-naturalness would be recognised. An evaluation study is reported where children aged 8–12 years worked with the software in contexts that typify computer use in classrooms, i.e. individually under adult guidance (n =? 44 children) or in pairs with a classmate (n = 48 children). They were observed while they did this. Reasoning about object fall was assessed via change from individual pre-tests administered prior to software usage to individual post-tests administered a few weeks afterwards. The children who worked with the software showed greater pre- to post-test gains in conceptual understanding than control children (n =? 47 children), who lacked software experience. The gains were especially marked for the children who worked in pairs. The approach taken is contrasted with traditional approaches to conceptual change in school science, e.g. strategies that rely upon classroom experiments.  相似文献   
22.
Prostate cancer (PCa) incidence and mortality have decreased in recent years. Nonetheless, it remains one of the most prevalent cancers in men, being a disquieting cause of men's death worldwide. Changes in many cell signaling pathways have a predominant role in the onset, development, and progression of the disease. These include prominent pathways involved in the growth, apoptosis, and angiogenesis of the normal prostate gland, such as an- drogen and estrogen signaling, and other growth factor signaling pathways. Understanding the foundations of PCa is leading to the discovery of key molecules that could be used to improve patient management. The ideal scenario would be to have a panel of molecules, preferably detectable in body fluids, that are specific and sensitive biomarkers for PCa In the early stages, androgen deprivation is the gold standard therapy. However, as the cancer progresses, it even- tually becomes independent of androgens, and hormonal therapy fails. For this reason, androgen-independent PCa is still a major therapeutic challenge. By disrupting specific protein interactions or manipulating the expression of some key molecules, it might be possible to regulate tumor growth and metastasis formation, avoiding the systemic side effects of current therapies. Clinical trials are already underway to assess the efficacy of molecules specially designed to target key proteins or protein interactions. In this review, we address that recent progress made towards under- standing PCa development and the molecular pathways underlying this pathology. We also discuss relevant molecular markers for the management of PCa and new therapeutic challenges.  相似文献   
23.
This study focused on violent and prosocial behaviors by adolescents toward parents and teachers, and the relation between such behaviors and adolescents’ perceptions about the family and school environment. Gender differences in child‐to‐parent violence and student‐to‐teacher violence were also studied. The sample comprised 687 adolescents from secondary schools in the province of Gipuzkoa, Spain, aged between 12 and 16 years. Participants responded to the relationship domains of the Family Environment Scale and the Classroom Environment Scale, among other instruments. A positive family relationship was related to less violent and more prosocial behavior toward parents. However, a positive classroom relationship was associated only with more prosocial behavior toward teachers. The results show that criminal and antisocial behaviors had a mediating influence on the relation between family and school relationships and violence against authority. The implications for intervention and prevention programs are discussed.  相似文献   
24.
This pilot-study aimed to assess a psychoeducational program for staff in care homes. The program was designed to increase knowledge regarding dementia care, promote skills to integrate motor and multisensory stimulation in daily care, and develop coping strategies to manage emotional work-related demands. Six staff members received eight psychoeducational sessions held fortnightly and individualized assistance during the provision of morning care to six residents with dementia. An audio-recorded focus group interview with staff and video recordings of residents' behavior during morning care were made and used to assess the program. Staff reported several benefits: acquisition of new knowledge; demystification of preexisting beliefs related to dementia; group cohesion; self-worth feelings; and positive coping. A trend towards improvements at residents' levels of interaction was found. The findings suggest the need of interventions to go beyond the objectives exclusively centered on staff education and the promotion of residents' well-being. This should be achieved by also allowing workers to feel supported and empowered.  相似文献   
25.
Establishment of higher education institutions and new firm entry   总被引:1,自引:0,他引:1  
The presence of universities has generally been associated with technological entrepreneurship. But what is the real impact of new universities on the levels of firm creation in a region? The present paper uses policy evaluation methodologies and longitudinal data on the establishment of higher education institutions in Portuguese municipalities for the period 1992-2002 to examine its effect on entry rates of new firms in different sectors. We find that the establishment of a new university has a positive and significant effect on subsequent levels of knowledge based firm entry in municipalities, and a negative effect on the levels of entry in other sectors, such as low-tech manufacturing.  相似文献   
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27.
Little is known about the influence of different types and sources of social support on physical activity in adolescents. The aim of this study was to analyse the association between physical activity and different types and sources of social support in adolescents. The sample consisted of 2,859 adolescents between 14–19 years of age in the city of João Pessoa, in Northeastern Brazil. Physical activity was measured with a questionnaire and social support from parents and friends using a 10-item scale five for each group (type of support: encouragement, joint participation, watching, inviting, positive comments and transportation). Multivariable analysis showed that the types of support provided by parents associated with physical activity in adolescents were encouragement for females (P < 0.001) and adolescents between 14–16 years of age (P = 0.003), and transportation (P = 0.014) and comments (P = 0.037) for males. The types of social support provided by friends were: joint participation in male adolescents (P < 0.001) and in these 17–19-year-olds (P < 0.001), and comments in both genders (males: P = 0.009; females: P < 0.001) and 14–16-year-olds (P < 0.001). We conclude that the type of social support associated with physical activity varies according to its source, as well as the gender and age of the adolescents.  相似文献   
28.
The present work describes an experience of educational innovation in a university context. Its aim was to determine the relationship between students’ frequency of use of online self-assessment with feedback and their final performance on the course, taking into account both learners’ motivation and perceived usefulness of these resources for their learning process. Furthermore, we studied the relationship between metacognitive variables and academic performance and/or execution of activities aimed at learning the course content. To this end we created self-assessment material with the Hot Potatoes educational program and assessed the degree to which students took advantage of the tool, their satisfaction with it and their perceived knowledge, using ad hoc questionnaires. The results indicate better academic performance in those students that use interactive self-assessment. It should be pointed out that even students with low motivation levels made use of this teaching tool. Finally, a relationship was found between metacognitive variables and students’ effort and performance. We discuss the need to include self-assessment in the curriculum, with a view to improving students’ metacognitive knowledge.  相似文献   
29.
Teachers play a key role in creating effective conditions for students to succeed in school. The quality of student–teacher relationships is consistently associated with social, emotional, behavioural and academic adjustment, and this is even more relevant for students with special educational needs (SEN), considering these students’ emotional, social and learning vulnerabilities. This study aimed to examine the associations between students’ externalising and internalising behaviour, social skills and academic performance, and teachers’ perceptions of conflict and closeness in their relationships with students with and without SEN. Data regarding 360 students in Year 3, Year 5 and Year 7 (169 students with SEN) were collected. Teachers (n = 74) reported on the student–teacher relationship and students’ social skills, behaviour problems and academic performance. Special education teachers (n = 38) provided information regarding the diagnosis and profile of functioning of students with SEN. Results showed that teachers’ reports of students’ social skills and externalising problems were the strongest predictors of closeness and conflict. Internalising problems and SEN status also predicted decreased closeness, despite smaller effects. Taken together, findings support the importance of professional development opportunities focusing on facilitating teachers’ relationships with students with perceived challenging behaviour.  相似文献   
30.
In this article we present findings from the evaluation study of a nation-wide school renovation programme in Portugal. The aim is to analyse policy implementation, taking into account school community participation, discussing how the programme requirement to involve users in the renovation was met, examining perceptions of the programme’s pedagogical principles and the impact on teaching and learning models. The analysis shows that the upgrading of schools increased pride in and responsibility for the school. But teaching practices in schools remain set in a traditional mould. Tensions remain between the objectives defined at the political level and effective conditions for learning.  相似文献   
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