Risk of venous thromboembolic disease in postmenopausal women taking oral or transdermal hormone replacement therapy

Objective  

The influence of hormone replacement therapy (HRT) on hemostasis processes depends on the type of hormone, the combination of doses, the time of taking HRT, and the route of administration (oral, transdermal, implanted). The aim of the current study was to assess some parameters of coagulation, especially tissue factor pathway inhibitor (TFPI) and tissue factor (TF) in postmenopausal women using oral or transdermal HRT.     

Chaiqin Chengqi Decoction decreases IL-6 levels in patients with acute pancreatitis

Objective  

In this paper, we investigated the effect of the traditional Chinese medicine Chaiqin Chengqi Decoction (CQCQD) on serum cytokines in acute pancreatitis (AP) patients.     

A Comprehensive Analysis of High School Genetics Standards: Are States Keeping Pace with Modern Genetics?

Science education in the United States will increasingly be driven by testing and accountability requirements, such as those mandated by the No Child Left Behind Act, which rely heavily on learning outcomes, or "standards," that are currently developed on a state-by-state basis. Those standards, in turn, drive curriculum and instruction. Given the importance of standards to teaching and learning, we investigated the quality of life sciences/biology standards with respect to genetics for all 50 states and the District of Columbia, using core concepts developed by the American Society of Human Genetics as normative benchmarks. Our results indicate that the states' genetics standards, in general, are poor, with more than 85% of the states receiving overall scores of Inadequate. In particular, the standards in virtually every state have failed to keep pace with changes in the discipline as it has become genomic in scope, omitting concepts related to genetic complexity, the importance of environment to phenotypic variation, differential gene expression, and the differences between inherited and somatic genetic disease. Clearer, more comprehensive genetics standards are likely to benefit genetics instruction and learning, help prepare future genetics researchers, and contribute to the genetic literacy of the U.S. citizenry.     

运用深度学习提高21世纪能力

"深度学习"是个人将在一个情境中学习的内容迁移应用于新情境的过程。深度学习通常是个人在与他人分享学习和互动中发生的,其形成的知识是可迁移的,包括学科内容的知识和为何、何时、怎样用这些知识来解决问题。我们将这样的知识和技能的结合体称为"21世纪能力",这些能力是根据学科领域的基本原理以及这些原理之间的相互关系所提出的,而不是孤立的、肤浅的事实或程序。支持迁移的正是人们将交织在一起的知识和技     

小学语文教科书中的爱国主义语篇的概念意义构建研究

人教版语文第一册中有四篇课文是以传递爱国主义价值观为宗旨的。选取其中《我多想去看看》作为研究对象,运用符际互补理论框架,研究如何通过文字和图像符号系统的相互作用和相互配合,形成连贯的语篇,分析结果表明,文字图像之间的符际关系着重在"国旗"、"地点"、"升旗仪式"以及"观礼"等方面;在小学语文教材中可以通过文字和图像符号系统的互补形成连贯的多模态语篇并传导主流价值观。     

基于转化医学模式下高等中医院校生物化学与分子生物学教学改革刍议

转化医学是近几年国际医学健康领域提出的新概念,注重基础研究的成果更快地向临床应用转化。本文针对当前高等中医药教育中存在的问题,探讨将转化医学的理念渗透到包括生物化学与分子生物学在内的医学基础课程中的必要性及可行性,总结了实施的具体方法与对策,以期进一步推动高等中医药教育的合理化发展和优秀高等中医药人才的培养。     

Water, steam and change: the roles of land drainage, water supplies and garden fountains in the early development of the steam engine

The history of the steam engine is generally linked to that of the Industrial Revolution. This article seeks to uncouple this seemingly necessary link by examining other contexts in which the steam engine was introduced and developed.     

Child abuse potential in parents with histories of substance use disorder

OBJECTIVE: To examine the relationship between parental history of substances use disorders (SUDs) and abuse potential. METHOD: Milner's (1986) Child Abuse Potential Inventory (CAPI) was administered to fathers and mothers (with and without histories of SUDs) of 10- to 12-year-old boys. RESULTS: Fathers and mothers with lifetime histories of SUDs had higher Abuse Scale scores and were more likely to score in the Elevated range (as determined by clinically significant cutoff scores) than parents without such histories. No differences were found between parents with current diagnoses of SUD and those with past (but not current) histories of SUD. Fathers and mothers with a partner who had a history of SUD were more likely to score in the Elevated range, regardless of their own SUD histories. Separate regression models revealed that, for both fathers and mothers, emotional dysregulation (positive and negative affectivity) predicted Abuse Scale scores. Additional contributors to Abuse Scale scores were SUD status in fathers, and lack of involvement with the child in mothers. CONCLUSIONS: History of SUDs in both fathers and mothers increases abuse potential. Contributors to abuse potential differed in fathers and mothers, underscoring the importance of examining parents separately in child maltreatment research.     

保护工作的干预警示系统:医学专业的经验

文物保护工作者的重要职责之一是了解保护干预措施中所使用材料和方法的有效性及安全性。无论是真实地操作过程,还是在实验中,材料科学与材料测试都可为保护工作者提供支持。但现实工作中,情况是复杂多变、难以适应的,由此将不可避免地造成一些难以预测的积极或消极、短期或长期的后果。本文借鉴了医学领域所使用的警示报告系统,提出保护材料和方法的干预警示系统。在保护工作中,通过系统化的过程,利用保护工作者观察到的情况和工作经验,有效并及时地扩大整个藏品保护领域对具体干预措施的全方位理解。本文还讨论了成功的警示结构在专业、组织和文化方面的先决条件。