Recent developments in microfluidic synthesis of artificial cell-like polymersomes and liposomes for functional bioreactors

Recent advances in droplet microfluidics have led to the fabrication of versatile vesicles with a structure that mimics the cellular membrane. These artificial cell-like vesicles including polymersomes and liposomes effectively enclose an aqueous core with well-defined size and composition from the surrounding environment to implement various biological reactions, serving as a diverse functional reactor. The advantage of realizing various biological phenomena within a compartment separated by a membrane that resembles a natural cell membrane is actively explored in the fields of synthetic biology as well as biomedical applications including drug delivery, biosensors, and bioreactors, to name a few. In this Perspective, we first summarize various methods utilized in producing these polymersomes and liposomes. Moreover, we will highlight some of the recent advances in the design of these artificial cell-like vesicles for functional bioreactors and discuss the current issues and future perspectives.     

Idea generation in biomedical engineering courses using Design Heuristics

ABSTRACT

With increasing demand for improved medical equipment and healthcare, next-generation biomedical engineers need strong design skills. Equipping biomedical engineering students with tools for idea generation and development can increase student design success. Design Heuristics are an ideation tool developed through empirical studies of product designs. While identified in the mechanical engineering space, Design Heuristics may be applicable in biomedical engineering design. In our study, we implemented a Design Heuristics session during upper-level undergraduate and first-year graduate biomedical engineering design courses. We examined the applicability of Design Heuristics within individual and team concept generation contexts. The findings demonstrated that biomedical engineering students were able to use Design Heuristics to generate multiple concepts, and that initial concepts produced using Design Heuristics were carried over into final team design. The results support the applicability of Design Heuristics to student idea generation in biomedical engineering design.     

二十世纪日本汉学界之荀子名学研究综述

在先秦时期,除了名家和墨家之外,在名学研究方面,其成就最大的当属荀子。荀子对于先秦名学之贡献主要是进一步批判和发展名家和墨辩之名学,使儒家之名学更加严谨。然而,历来有关荀子之研究多着眼于其心、性、天、礼等之探讨,而疏于抉发其名学之义蕴。直到近年来,由于大陆学界积极挖掘中国古代之逻辑思想,以免西方逻辑专美于前,于是有关中国逻辑史或逻辑思想之论着,如雨后春笋般出现。此等有关中国逻辑论者之研究对象主要为先秦时期讨论名实辩说之篇章,尤其是公孙龙、墨辩和荀子名学之研究。此外,由于一些国外学者之参与,使得中国古代逻辑之研究,尤其是关于荀子名学之研究,如今已成一较为普遍之现象。有关荀子之研究,日本汉学界已作出极为可喜之成绩。唯历来有关荀子之研究,日本汉学界多着重其心、性、天、礼或政治、伦理学说之阐述,而较疏于其名学之研究。然而,就目前已发表之论着而言,无论是在厘清荀子之哲学立场或对于名学之分析等,亦颇有其独到之处,值得吾人借镜。     

Cross-Cultural Adaptation and Psychometric Properties of the Portuguese Version of the Life Skills Scale for Sport

ABSTRACT

This research adapted the Life Skills Scale for Sport (LSSS) into Portuguese and provided evidence for its construct validity. Study 1 included four translators and five academics who developed a Portuguese version of the LSSS (P-LSSS). During this study, evidence for the content and substantive aspects of construct validity was provided using an expert panel and 25 sports participants. Study 2 included 413 participants that completed the P-LSSS. Within this study, evidence for the structural aspect of construct validity was provided via factor analyses. Study 3 included 134 participants who completed the P-LSSS and a measure of motivation. This study provided evidence for the external aspect of construct validity, with results showing more self-determined motivation had positive relationships with participant’s life skills development. Overall, our findings provided evidence for the construct validity of P-LSSS scores. Researchers and practitioners can use the P-LSSS to assess life skills development within sports participants.     

Educational leadership and pupil achievement in primary education

Educational leadership can be defined as the ability of a principal to initiate school improvement, to create a learning-oriented educational climate, and to stimulate and supervise teachers in such a way that the latter may execute their tasks as effectively as possible. In 1989, 1993, and 1998, teacher perceptions of educational leadership of principals in Dutch elementary education were evaluated by means of a Rasch-scale. It turned out that the educational leadership of Dutch principals has grown considerably. In both 1989 and 1993 the effect of educational leadership on pupil achievement was investigated. While in 1989 no significant relationship was found, the results of 1993 show a significant relationship between educational leadership and average pupil achievement over 3 successive years corrected for school environment.     

Explorations in promoting conceptual change in electrical concepts via ontological category shift

Chi (1992, 1993) Chi et al. (1994) suggests that many of the difficulties encountered by students in learning Physics concepts arise because they attribute the ontology of material substances to these concepts. These concepts are actually a special type of process - 'Constraint-Based Interactions' (CBI). Slotta and Chi (1996) reported on a study where a group of students explicitly trained in the CBI ontology showed significant gains over a control group in problem solving performance in eight simple electric circuit problems. This paper reports on a series of four studies which explore the usefulness of the ontological categorization framework in investigating students' alternative conceptions of electric circuits and in developing a teaching strategy for promoting conceptual change in the learning of basic electric circuitry concepts.