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The experiences of medical students, residents, and faculty with a computerized literature searching system were evaluated. Third-year medical students, internal medicine and family practice residents, and full-time and voluntary faculty at one medical school had the opportunity to use a full-text and bibliographic medical literature retrieval system free of charge for an eleven-month period. Subjects conducted nearly nine thousand literature searches over a period of 942 system hours. Questionnaire data showed that participants could learn to use and would use an electronic information system, felt capable of using the system, utilized the system for a variety of purposes and in a number of different ways, and viewed the system as a valuable tool in searching the medical literature. The results are discussed in the context of the educational needs of the four user-groups and medical education planning by institutions.  相似文献   
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Biomimetic scaffolds approaching physiological scale, whose size and large cellular load far exceed the limits of diffusion, require incorporation of a fluidic means to achieve adequate nutrient/metabolite exchange. This need has driven the extension of microfluidic technologies into the area of biomaterials. While construction of perfusable scaffolds is essentially a problem of microfluidic device fabrication, functional implementation of free-standing, thick-tissue constructs depends upon successful integration of external pumping mechanisms through optimized connective assemblies. However, a critical analysis to identify optimal materials/assembly components for hydrogel substrates has received little focus to date. This investigation addresses this issue directly by evaluating the efficacy of a range of adhesive and mechanical fluidic connection methods to gelatin hydrogel constructs based upon both mechanical property analysis and cell compatibility. Results identify a novel bioadhesive, comprised of two enzymatically modified gelatin compounds, for connecting tubing to hydrogel constructs that is both structurally robust and non-cytotoxic. Furthermore, outcomes from this study provide clear evidence that fluidic interconnect success varies with substrate composition (specifically hydrogel versus polydimethylsiloxane), highlighting not only the importance of selecting the appropriately tailored components for fluidic hydrogel systems but also that of encouraging ongoing, targeted exploration of this issue. The optimization of such interconnect systems will ultimately promote exciting scientific and therapeutic developments provided by microfluidic, cell-laden scaffolds.  相似文献   
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This study seeks to extend our knowledge of export market orientation (EMO) in the context of British universities with regard to recruitment of international students. Export marketing remains an area of limited focus in the marketization of higher education literature. The study predominantly follows a quantitative research design using survey methods. A sample of British universities was studied and partial least-squares analysis was performed. The findings indicate that four export higher education-specific variables are important drivers of EMO in universities. The paper also confirms EMO's direct effects on university export performance and its indirect effects mediated through university international reputation. In light of these findings, a number of implications are advanced for university management. The study also makes important theoretical contributions: it contributes to a growing body of literature on marketing of higher education; it enriches the export marketing literature by examining EMO in a service setting and it adds to the EMO–export performance relationship by examining the mediating role of international reputation. The findings are limited to British universities. Therefore, they may not be generalizable to other geographical areas. In addition, the results of this study were obtained from a small sample size and generalization of the findings to other higher education institutions should be made with caution.  相似文献   
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High impact forces during gymnastic landings are thought to contribute to the high rate of injuries. Lower limb joint flexion is currently limited within gymnastic rules, yet might be an avenue for reduced force absorption. This study investigated whether lower limb flexion during three gymnastic landings was related to force. Differences between landings were also explored. Twenty-one elite women's artistic gymnasts performed three common gymnastic techniques: drop landing (DL), front and back somersaults. Ankle, knee, and hip angles, and vertical ground reaction force [(vGRF) magnitude and time to peak], were measured using three-dimensional motion analysis and force platform. The DL had significantly smaller peak vGRF, greater time to peak vGRF and larger lower limb flexion ranges than landing from either somersault. Peak vGRF and time to peak vGRF were inversely related. Peak vGRF was significantly reduced in gymnasts who landed with greater hip flexion, and time to peak was significantly increased with increasing ankle, knee, and hip flexion. Increased range of lower limb flexion should be encouraged during gymnastic landings to increase time to peak vGRF and reduce high impact force. For this purpose, judging criteria limitations on lower limb flexion should be reconsidered.  相似文献   
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Clean air policies in China have substantially reduced particulate matter (PM2.5) air pollution in recent years,primarily by curbing end-of-pipe emissions.Howev...  相似文献   
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