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151.
Several new tools to obtain three-dimensional information from unorganized image sets are now available for the public use. The main advantage of this software, which is based on dense stereo matching, is the possibility to generate 3D content without the need of high-cost hardware (e.g. 3D scanning devices). Nevertheless, their use in real-world application domains (like cultural heritage) is still not very diffused, due to the non-straightforward usability of the raw data produced. In this paper, we investigate the use of automatic dense stereo reconstruction tools for the monitoring of an excavation site. A methodology for the effective acquisition and processing of data is presented. In addition, the results of the data assessment demonstrate the repeatability of the data acquisition process, which is a key factor when qualitative analysis is performed. The use of three-dimensional data is integrated in an open source mesh processing tool, thus showing that a spatio-temporal analysis can be performed in a very intuitive way using off-the-shelf or free/open digital tools. Moreover, the use of peculiar rendering and the creation of snapshots from arbitrary points of view increase the amount of documentation data, and suggest a perfect integration of data produced with dense stereo matching in the future standard documentation for excavation monitoring.  相似文献   
152.
Spatially and temporally resolved delivery of soluble factors is a key feature for pharmacological applications. In this framework, microfluidics coupled to multisite electrophysiology offers great advantages in neuropharmacology and toxicology. In this work, a microfluidic device for biochemical stimulation of neuronal networks was developed. A micro-chamber for cell culturing, previously developed and tested for long term neuronal growth by our group, was provided with a thin wall, which partially divided the cell culture region in two sub-compartments. The device was reversibly coupled to a flat micro electrode array and used to culture primary neurons in the same microenvironment. We demonstrated that the two fluidically connected compartments were able to originate two parallel neuronal networks with similar electrophysiological activity but functionally independent. Furthermore, the device allowed to connect the outlet port to a syringe pump and to transform the static culture chamber in a perfused one. At 14 days invitro, sub-networks were independently stimulated with a test molecule, tetrodotoxin, a neurotoxin known to block action potentials, by means of continuous delivery. Electrical activity recordings proved the ability of the device configuration to selectively stimulate each neuronal network individually. The proposed microfluidic approach represents an innovative methodology to perform biological, pharmacological, and electrophysiological experiments on neuronal networks. Indeed, it allows for controlled delivery of substances to cells, and it overcomes the limitations due to standard drug stimulation techniques. Finally, the twin network configuration reduces biological variability, which has important outcomes on pharmacological and drug screening.  相似文献   
153.
This paper presents a deformative and structural study of the Guarneri ‘del Gesù’ violin (1743) known as the ‘Cannone’. A structural assessment is fundamental to understanding the violin's compatibility with its residual function of musical instrument. The tuning of the instrument to a modern playing pitch during concerts could, in fact, cause stress resulting in plastic deformations of its structure. In order to understand the stress level to which the violin is subjected when tuned, several tests were performed. The forces acting on the bridge were measured, the geometry of the un-strung and of the tuned violin were acquired with a tri-dimensional scanner, the violin deformation was assessed by means of the computed surface deviation mesh and by measuring the deformation in selected lines, several sections of the violin were cut from the digital model and stress exerted on the sections was computed. The stress exerted on the neck, scroll and body were found to be very limited. More significant, albeit at a low level, was the stress exerted under the bridge between the sound holes. Mechanical stress exerted after tuning was found to be safe for the violin, if applied for a limited amount of time. This does not mean that the violin can be played freely, because the real strength of the material used in the violin is not known and mechanical stress during a concert must be added to time (viscous behaviour), moisture content variation (mechano-sorptive behaviour) and hygro-thermal stress, thus worsening the condition. The method presented here could be applied to compute the level of stress of any violin.  相似文献   
154.
In a context of stagnation of the level of health-enhancing physical activity in Europe, this study examines the geographical stratification of sports participation and physical activity (PA) at the regional level in 28 European countries. While previous research has focused on the national approach, this study considers the regional level across 208 European regions. Individual survey data from the Eurobarometer 80.2 is combined with a regional-level approach to the 208 regions to quantify sports participation and PA at the regional level. The results show important differences and a geographical stratification of sports participation and PA among the European regions, albeit following different patterns. In particular, a north–south gap is identified in terms of PA rates and an east–west gap is detected in terms of sports participation levels. Applying the cluster technique, a taxonomy of four different European regions is developed considering both types of indicators. Finally, the existence of sports spatial spillovers among regions is verified, obtaining a positive autocorrelation among neighbouring regions for being involved in PA and sporting activities. The results may have significant implications in terms of policy measures to improve health through PA and sports participation at the regional level in Europe.  相似文献   
155.
Giunti  Marco 《Metascience》2017,26(1):117-121
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156.
Although Venice is regarded as being one of the most important centres of glass manufacture and trade in Western Europe, little is known about the origins of the Venetian glassmaking. Some archaeologists suggest there is a continuity in the history of glass making, in its transplantation from the Roman centres of the mainland (Altino and Aquileia), first to some islands of the lagoon, and later to the town. Some others, instead, think that there was no continuity at all and that the art of glassmaking was imported in Venice from the Islamic glass factories of the Middle East. Of great help in answering this and other technological questions is the information about the composition of ancient glass from well-dated excavations that allows to conclude on the early technology, sources of raw materials and long-distance trade. Some significant glass findings, including fragments of pots used for glass melting, were found on the island of Torcello and, more recently, in two emergency excavations in the historic centre of Venice. In this paper, the chemical composition of a large set of glass findings (and related materials) from the Venetian lagoon dating from the 7th to the 13th centuries is determined by X-ray microanalysis in order to throw new light on the glassmaking technology in the early centuries of the Venetian tradition. The results show that in this period there occurred a gradual transition from the Roman technique (a two-ingredient formulation with silica-lime sand and natron as a fluxer), towards the use of silica sand and soda plant ash. There is evidence, therefore, for a production continuity with the Roman period (melting pots and glass scraps with a natron-based composition), yet restricted to transparent blown items. No evidence was found for a local production of glass tesserae for the mosaics of the church of St. Maria Assunta in Torcello.  相似文献   
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159.
This article investigates the experience of 229 low-income students of color who participated in an innovative high school internship program between 2011 and 2015. Using mixed methods (interviews, observations, and survey), the authors aim to understand the types of knowledge, information, and supports these students develop and expand in relation to careers and the college-going process. The authors draw on students' community cultural wealth to highlight the way the internship program supports students' aspirational, navigational, linguistic, resistant, and social capital.  相似文献   
160.
On the basis of a knowledge management perspective, this paper expands the literature on new ventures’ capabilities by considering how these firms fill knowledge gaps and develop the technological, marketing, management, and ICT capabilities they need to compete. In particular, this paper investigates the role of networks in these dynamics. Although new technology-based firms have great potential to introduce innovative products into the market, they might suffer from more critical knowledge gaps and capability weaknesses than established firms. The results of a quantitative investigation of an original data set of more than 400 Italian new ventures specializing in high-tech industries show that these firms acquire knowledge to support their capability growth mainly through the management of intense relations with multiple external sources of knowledge. In addition, capability development is supported by the variety of founders’ industry experience and the presence of young graduates among the founding team.  相似文献   
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