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Although high levels of sitting time are adversely related to health, it is unclear whether moving from sitting to standing provides a sufficient stimulus to elicit benefits upon markers of chronic low-grade inflammation in a population at high risk of type 2 diabetes (T2DM). Three hundred and seventy two participants (age = 66.8 ± 7.5years; body mass index (BMI) = 31.7 ± 5.5kg/m2; Male = 61%) were included. Sitting, standing and stepping was determined using the activPAL3TM device. Linear regression modelling employing an isotemporal substitution approach was used to quantify the association of theoretically substituting 60 minutes of sitting per day for standing or stepping on interleukin-6 (IL-6), C-reactive protein (CRP) and leptin. Reallocating 60 minutes of sitting time per day for standing was associated with a ?4% (95% CI ?7%, ?1%) reduction in IL-6 (p = 0.048). Reallocating 60 minutes of sitting time for light stepping was also associated with lower IL-6 levels (?28% (?46%, ?4%; p = 0.025)). Substituting sitting for moderate-to-vigorous (MVPA) stepping was associated with lower CRP (?41% (?75%, ?8%; p = 0.032)), leptin (?24% (?34%, ?12%; p ≤ 0.001)) and IL-6 (?16% (?28%, 10%; p = 0.036). Theoretically replacing 60 minutes of sitting per day with an equal amount of either standing or stepping yields beneficial associations upon markers of chronic-low grade inflammation.  相似文献   
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The objective of the research on which this article reports was to evaluate the training conditions of primary school teachers in rural Cameroon, so as to identify alternative paths towards their qualification through informal learning in the workplace and outside. Following Denzin’s (2009) between-methods triangulation approach, quantitative techniques, including statistical analyses and standardised questionnaires, were applied in addition to qualitative techniques, such as face-to-face interviews and observations of practising teachers and experts. The article presents the most common learning strategies of teachers in rural areas of Cameroon and recommends seminal solutions for teacher education. It can be concluded that informal learning in the workplace corresponds to traditional ways of learning in collectivist-oriented, oral societies in rural areas. Therefore, the combination of informal methods with formal structures of teacher education could improve the current educational system of many African countries, and provide a solution to meet the high demand for qualified staff within restricted budgets.  相似文献   
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This study examined associations between caregiver talk and language skills in full term (FT) and preterm (PT) children (n = 97). All‐day recordings of caregiver–child interactions revealed striking similarities in amount of caregiver talk heard by FT and PT children. Children who heard more caregiver talk at 16 months demonstrated better knowledge‐ and processing‐based language skills at 18 months. The unique contributions of caregiver talk were tempered by medical risk in PT children, especially for processing speed. However, there was no evidence that birth status or medical risk moderated the effects of caregiver talk. These findings highlight the role of caregiver talk in shaping language outcomes in FT and PT children and offer insights into links between neurodevelopmental risk and caregiver–child engagement.  相似文献   
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Internationalisation, competition and performance orientation are nowadays essential in the managing and financing of universities. This pattern has intensified with the austerity measures and fiscal consolidation that followed the financial crisis in 2008. This article examines the academic labour process and career making of academics from a gender perspective. Based on findings deriving from an Icelandic University, we argue that the austerity measures and increased focus on becoming one of the top universities in the world has changed the official responsibilities of academics. We show how ‘academic housework’ affects academic capital and how the amount of academic housework is unequally distributed between senior academics and newcomers. While the majority of academics conform to this contemporary academic system, marginalised groups put up some resistance but with limited success.  相似文献   
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Asia Pacific Education Review - The paper considers the importance of epistemic justice in democratic life, and the significance of education as a key space to foster the relevant epistemic...  相似文献   
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A common way of estimating measurement quality is the split-ballot multitrait–multimethod (SB-MTMM) approach. However, this approach leads often to non-convergence or improper solutions when using a 2-group design, whereas the 3-group design performs better. Nevertheless, the 3-group design is rarely implemented because it makes it complicated for applied researchers to use the data. Therefore, we propose to draw groups of unequal sample sizes: two larger groups and one third group as small as possible. Using Monte Carlo simulations and real data analyses, we investigate how well such a design works and which size is needed for the third group. Our results suggest that a 3-group SB-MTMM design with smaller size for the third group (reducing till 5–10%) leads to similar levels of accuracy and no large changes in the model or quality estimates.  相似文献   
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Interested in collaboratively exploring the potential of EAC-CPF, the Beinecke Library at Yale and the Houghton Library at Harvard embarked on a year-long project to gain experience with the new standard and, in the process, strengthen connections between disparate but deep holdings of lexicographer Samuel Johnson (1709–1784) and his circle. The project team set out to document metadata best practices while developing and maintaining one set of records and to discover the practical limits and possibilities of rich content within the EAC-CPF context. This article outlines the project's challenges, lessons learned, and remaining questions.  相似文献   
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