Anti-Atherosclerotic and Anti-Inflammatory Effects of Curcumin on Hypercholesterolemic Male Rabbits

Curcumin has a potent antioxidant and anti-inflammatory properties that may suppress inflammatory component of atherosclerosis. It has been demonstrated that curcumin derivatives can reduce the formation of arterial fatty streaks in cholesterol-fed rabbits. Therefore in this study we evaluated the protective effects of Curcumin on the progression of atherosclerosis. 20 mature rabbits were included for this study; they were randomly divided into four groups each of 5. Group 1: (normal control) were fed corn pellets diet and tab water, group 2: (high cholesterol diet control) were kept on cholesterol rich diet (2% cholesterol) and tab water. Group 3: (cholesterol and rosuvastatin treated group) were kept on cholesterol rich diet (2% cholesterol) and 2.5 mg/kg/day Rosuvastatin dispersed in DW and given orally, group 4: (cholesterol and curcumin treated group) were kept on cholesterol rich diet (2% cholesterol) and 0.2% curcumin added with corn pellets. The study continued for 12 weeks then assessment of serum level of high sensitive C-reactive protein, ICAM1, VCAM1 and PCSK9 was carried out at the end of the study. Total antioxidant activity of curcumin was also determined. Histopathological examination of aortic tissues for atherosclerotic changes was also carried out. Atherogenic (cholesterol rich diet) induced an increment in serum level of TC, LDL, VLDL and TG with concomitant decrement in serum level of HDL and increased atherogenic index. Treatment with curcumin produced substantial reduction in serum TC, LDL, TG with no effect on HDL level thus decreased atherogenic index. Rabbits treated with curcumin showed a significant reduction in the serum level of high sensitive C-reactive protein, ICAM1, VCAM, PCSK9 serum expression and aortic total antioxidant capacity. Curcumin has a potent anti-inflammatory and anti- oxidant effects against atherosclerosis so exerts a protective role by decreasing lipid oxidation and inflammatory markers.     

How accurate are cited references in Iranian peer‐reviewed journals?

The references cited in scientific articles are as important as any other part of the paper, because of their usefulness to the scientific community and to abstracting and indexing services and citation databases. I studied inaccuracies in references and in‐text citations in sample of 97 of the 519 peer‐reviewed journals accredited by the Iranian National Commission for Journal Accreditation Policy (Ministry of Research, Science and Technology). The target journals published 2,980 articles with 74,577 cited references and 108,151 in‐text citations. The results showed 36.6% as the average percentage error rate (range 5.6% to 61.3%). The mean number of errors in cited reference and in‐text citations was 2.7 per article, and the mean number of errors per journal was 690. For the entire sample of articles, 4,369 in‐text citations did not match any source in the list of references (4%), and 8,683 cited references did not match any in‐text citation (11.6%). The stakeholders in scholarly communication, especially authors, pay insufficient attention to the accuracy of bibliographic references. Peer‐reviewed journals should encourage the use of standardized journal policies and quality‐control measures regarding peer review, data quality and accuracy.     

School-university partnerships: a new recipe for creating professional knowledge in school

This paper first reviews the literature on school-university partnerships to evaluate and describe challenges and paradigms of Japanese approaches to school-university partnerships in theory and practice. Secondly, it clarifies the role of three-year school-university partnership between the Nagoya University and the Tokai City Board of Education in the central Japan for creating an effective environment in schools for teachers to learn from each other and for developing more learning-centered education that focuses on the real needs of students. From this study it can be claimed that more effective relationships between Japanese school teachers and university researchers can be established through developing collaborative a school-based research framework especially through the process of jugyou kenkyuu (lesson study).     

Bibliometric Analysis of Gold Open Access in India

This study analyzes the current state of gold Open Access (OA) in India based on papers published in the Web of Science indexed journals. It specifically focuses on research output published in OA journals and examines the difference between gold OA and general research output for papers authored by Indian researchers. In order to analyze the Indian contribution of gold OA literature and compares with other countries, Web of Science?-Core Collection was used. There is an increasing trend of contributing research papers in OA journals by Indian researchers. Among the top 20 publishing countries India ranks 10th place in terms of the general research output, but secures 8th place in terms of gold OA papers. However, India's position in terms of share of gold OA publications is relatively higher than other leading countries of the world. Researchers in India mostly prefer to contribute their gold OA papers in Indian journals rather foreign journals and the proportion of gold OA research output in Clinical, Preclinical, Health, Life Sciences and Physicals Sciences is much higher than other disciplines such as Arts &; Humanities and Social Sciences. Since most of the research output in India is published in local journals, the study suggests further analyses of publications which are not published in Web of Science indexed journals.     

The resilience of the MBA in emerging economies: student motivations for wanting an MBA in China and the United Arab Emirates

In recent years, domestic demand for MBAs has fallen in most major Western markets but has increased or remained stable in emerging economies such as China and the United Arab Emirates (UAE), which are the two countries globally that host the largest numbers of international branch campuses. Thus, this research aimed to discover why students in China and the UAE still want an MBA. A survey questionnaire was completed by a total of 354 MBA students, at two universities in China and two universities in the UAE. Some of the results were surprising and unexpected. For example, recognition, prestige and networking – all key features in Chinese and Emirati societies – were found not to be key motivators for wanting an MBA. Instead, the desire to acquire knowledge and skills was the strongest motivator among respondents, accounting for 32.4 per cent of variance. This was followed by reasons associated with intrinsic benefits. The findings have implications for institutional strategy, curriculum design, program delivery and the marketing of programs.     

Gender and behavioural differences in Kuwait primary schools

Previous studies have found significant differences between the classroom behaviour of boys and girls. Most are within a single broad cultural context and little work has been done within an Arabic/Kuwaiti one. The main aim was to investigate the differences in behaviour between boys and girls in Kuwait primary schools. Data were collected that provided comparisons across questionnaires between parent and teacher returns for over 430 students. Separate teacher observations of students (n = 671) and classroom researcher observations were also obtained. Significant differences were found across the scales, indicating higher levels of externalising misbehaviour among boys than girls. A comparison with three studies conducted in other cultural contexts using the same strengths and difficulties instrument as used in this study found similarities and differences in results between the behaviour of boys and girls.     

Phytoremediation of heavy metal polluted soils and water：Progresses and perspectives

Environmental pollution affects the quality of pedosphere, hydrosphere, atmosphere, lithosphere and biosphere. Great efforts have been made in the last two decades to reduce pollution sources and remedy the polluted soil and water resources. Phytoremediation, being more cost-effective and fewer side effects than physical and chemical approaches, has gained increasing popularity in both academic and practical circles. More than 400 plant species have been identified to have potential for soil and water remediation. Among them, Thlaspi, Brassica, Sedum alfredii H., and Arabidopsis species have been mostly studied. It is also expected that recent advances in biotechnology will play a promising role in the development of new hyperaccumulators by transferring metal hyperaccumulating genes from low biomass wild species to the higher biomass producing cultivated species in the times to come. This paper attempted to provide a brief review on recent progresses in research and practical applications of phytoremediation for soil and water resources. Project supported by the Higher Education Commission, Government of Pakistan for the faculty training under the R & D Project “Strengthening Department of Soil Science and Soil and Water Conservation” at the University of Florida, USA, a grant from the St. Lucie River Water Initiative (SFWMD contract No. OT060162), USA, in part, and the Program for Changjiang Scholars and Innovative Research Team in University (No.IRT0536), China     

Parents' attitudes towards inclusion of students with autism in Jordan

This study investigated the attitudes of parents in Jordan towards the inclusion of students with autism spectrum disorder (ASD) in public schools and what the parents believed to be the most important prerequisite of child-based skills for successful inclusion. A total of 148 parents were selected to complete the survey. The researchers explored whether variable demographic characteristics such as age, student's gender, parent's gender, education levels, monthly income, and high- or low-function ASD correlated with the attitudes of parents towards inclusion of students with ASD in public schools. The analyses revealed that the variables that correlated with parents' attitudes towards inclusion were education levels and high- or low-function ASD. The themes behind the parents' attitude for inclusion are discussed. With regard to the prerequisite skills for successful inclusion, the results indicated that parents recommended independent skills, playing skills, behavioural skills, imitation skills, routine skills, social skills, paying attention skills, language skills, and pre-academic and academic skills in that order.     

Optimized frequency-based foundation design for wind turbine towers utilizing soil-structure interaction

This study illustrates design optimization for multiple wind towers located at different villages in Alaska. The towers are supported by two different types of foundations: large mat or deep piles foundations. Initially, a reinforced concrete (RC) mat foundation was proposed. Where soil conditions required it, a pile foundation solution was devised utilizing a 30 in thick RC mat containing an embedded steel grillage of W18 beams and supported by 20-24 in grouted or un-grouted piles. For faster installation and lower construction cost, all-steel foundations were proposed for these remote Alaska sites. The new all-steel design was found to reduce the natural frequencies of the structural system due to softening the foundation. Thus, the tower-foundation system could potentially become near-resonant with the operational frequencies of the wind turbine. Consequently, the likelihood of structural damage or even the collapse is increased.A detailed 3D finite-element model of the tower-foundation-pile system with RC foundation was created using SAP2000. Soil springs were included in the model based on soil properties obtained from the geotechnical investigation. The natural frequency from the model was verified against the tower manufacturer analytical and experimental values. When piles were used, numerous iterations were carried out to eliminate the need for the RC and optimize the design. An optimized design was achieved with enough separation between the natural and operational frequencies. The design successfully avoids damage to the structural system, while eliminating the need for any RC in most cases.