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Anabel Bach Sebastian Wurster Dr. Katja Thillmann Prof. Dr. Hans Anand Pant Prof. Dr. Felicitas Thiel 《Zeitschrift für Erziehungswissenschaft》2014,17(1):61-84
The introduction of comparative tests in a low-stakes system was carried out in the expectation that the data feedback to schools would act as a stimulus for the development of the schools and the standard of classroom teaching. By contrast with the use of data to develop teaching, the use of data for personnel development has not yet been studied in Germany. On the basis of an on-line survey of head teachers and a paper-and-pencil survey of teaching staff, the study examines for the first time the extent to which comparative test data is used by head teachers for personnel development and as a means to plan in-service training in subject conferences, and what factors influence whether the data is used in this way. Of the head teacher characteristics which were studied (attitude in relation to the perceived usefulness of the data, qualifications, organisation and age of the head teacher), usefulness is the only characteristic which has a positive effect on the use of the data. The use of comparative test data to plan in-service training in subject conferences is positively influenced by data-wise leadership by the head teacher and by collaborative evaluation. 相似文献
53.
V. Thakur A. K. Anand U. Mukherjee D. Ghosh 《Indian journal of clinical biochemistry : IJCB》2003,18(2):27-33
Appropriate therapeutic measures can improve the life expectancy of patients with ovarian malignancy. There has been a pressing
need for serodiagnostic assays to enable, the close patient monitoring. Cancer Antigen 125 (CA125) has been described as a
useful marker in patient monitoring for ovarian malignancy. Keeping this in view, the present study was planned. 40 consecutive
female patients of ovarian carcinoma (mean age 52.4±10.7 years) were selected for serum CA125 analysis during the period of
year 1995–2001. The tumour marker concentration was compared with histologic types of ovarian tumour and the FIGO staging
of the disease. 25 healthy females (mean age 35.2–10.4 years) served as control. Mean serum CA125 concentrations in patients
with papillary serous adenocarcinoma(Mean±%CV 1571±121.5 U/ml) was much higher than patients with mucinous adenocarcinoma(775±78U/ml).
Mean serum CA125 concentration in endometrioid carcinoma was very high(2853±136 U/ml). The patient with clear cell carcinoma
however had shown moderate increase(60 U/ml). No correlation was found between serum CA125 concentration and the FIGO staging
of disease.
Quantitation of CA125 was most helpful in monitoring the response of treatment and followup of the patients after completion
of their treatment. Posttherapeutically its concentration showed more than 50% reduction in almost all (91.4%) patients (P<0.001).
Importantly these patients had also shown significant regression of the disease clinically and radiologically. 8.6% of patients
had shown static or increase in serum CA125 concentration which was associated with either clinically static or progressive
disease. Recurrence of the disease was noted in patients who had shown increase in serum CA125 concentration (biochemical
recurrence) in the followup
However, in our test population biochemical recurrence(increase in serum marker concentration) preceded the clinical or radiological
recurrence by an average of 6.5 months.
Kaplan meier survival analysis for evaluation of overall survival in our test subjects showed an overall survival of 32% at
one year and median survival of 9 months with confidence interval of 6.34 to 11.66. We conclude that serum CA125 is a useful
marker for monitoring the treatment and predicting an early recurrence of the disease in ovarian carcinoma patients. A study
in larger number of patients is needed to define its exact role in the management of the carcinoma ovary. 相似文献
54.
Anand Kumar Gayathri M. Rao Beena V. Shetty 《Indian journal of clinical biochemistry : IJCB》2016,31(3):357-358
Infantile tremor syndrome is seen worldwide more commonly in the developing countries. Although various protein energy malnutrition awareness programme being run in many of these countries including India yet there is persistence of this disease. Here we present a case of 13 month old female child who visited RAPCC paediatrics OPD of Govt. Wenlock Hospital Mangaluru with history of respiratory distress, fever, tremor in limbs and loss of milestones. On examination she had pallor, hyper pigmentation in axilla and toes. Investigatory findings showed megaloblastic erythroid hyperplasia, hemoglobin- 1.6 g % and CT scan of brain showed central atrophic changes. 相似文献
55.
Sleep Disturbance and Expressive Language Development in Preschool‐Age Children With Down Syndrome 下载免费PDF全文
Jamie O. Edgin Ursula Tooley Bianca Demara Casandra Nyhuis Payal Anand Goffredina Spanò 《Child development》2015,86(6):1984-1998
Recent evidence has suggested that sleep may facilitate language learning. This study examined variation in language ability in 29 toddlers with Down syndrome (DS) in relation to levels of sleep disruption. Toddlers with DS and poor sleep (66%, n = 19) showed greater deficits on parent‐reported and objective measures of language, including vocabulary and syntax. Correlations between sleep and language were found in groups with equivalent medical and social backgrounds and after control for relevant behavioral comorbidities, including autism symptoms. These results emphasize the important role of quality sleep in all children's expressive language development, and may help increase our understanding of the etiology of language deficits in developmental disorders, potentially leading to new treatment approaches. 相似文献
56.
Sepsis is associated with various metabolic derangements as a consequence of inflammatory response, ischemia and oxidative stress. Four parameters of relevance are procalcitonin (PCT), ischemia modified albumin (IMA) pH and lactate. The study was carried out to highlight the concomitant occurrence of sepsis, ischemia and lactic acidosis, all of which could have deleterious effects on organ function. 26 critically ill patients with a provisional diagnosis of sepsis were the test subjects. The control group had 25 apparently healthy volunteers. PCT, lactate and IMA were assayed. PCT was estimated on an automated analyser using electro-chemiluminescence. Lactate and pH were estimated on a blood gas analyzer. Serum IMA was estimated spectrophotometrically by Albumin Cobalt Binding Test. Statistical tools like students ‘t’ test and Venn diagram were employed to depict the outcome of the study. All critically ill patients had significantly higher IMA levels (0.96746 ± 0.73407) as compared to the control group (0.00728 ± 0.00895) with a p value of <0.0001. The Venn diagram was used to depict the finding that all 26 test subjects had elevated levels of IMA, of which PCT was elevated in 22 and lactate in 20. Both PCT and lactate were abnormal in 17 patients. The most significant observation was that all critically ill patients, irrespective of the presence of sepsis or lactic acidosis had elevated levels of IMA which is clearly indicative of the ubiquitous presence of oxidative stress. The Venn diagram is an elegant representation of the concurrent multiple pathophysiological processes which occur in critically ill patients. 相似文献
57.
The paper presents some findings of a study which surveyed the political attitudes and involvement of American scientists.We found an unambiguous rank ordering based on political orientation among the various subgroups of scientists. The greater the scientists' identification with basic science and the university, the greater the liberalism. However, the claim that scientific elites are more liberal than the rank-and-file and that physicists are the most liberal among natural scientists was not substantiated.The fear that a scientific-technological elite might become a dominant political elite was not reflected in the thinking of a large majority of our 1205 respondents. A majority expressed reservations about the skill and knowledge of the citizenry to understand and resolve the increasingly complex problems of our society, recognize that a separation of science and politics is not attainable or even desireable, but remain somewhat uneasy with the new situation in which their work has become so enmeshed with policy concerns.The traditional norm system of science continues to receive substantial support and takes precedence over either the concern about the social consequences of certain types of “dangerous” knowledge, or the costs that heavy investments in basic science involve. We find that scientists are largely prepared to sacrifice the norm of communality at the altar of nationalism. The clash between an internal ideology of science that values disinterested search for knowledge and an external ideology of society which focuses on utility presents a continuing dilemma. 相似文献
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