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81.
This research primarily examines the stages hypothesis of the process of technology adoption by management personnel of organizations in the supply chain sector involving the Initiation, Experimentation, and Implementation stages. Further, this research examines key antecedents that may influence the various stages, including top management support, external pressure, and organization size. Using responses provided by top management representatives of 210 supply chain organizations on their organizations’ engagement with Radio Frequency Identification (RFID) technologies, this research finds that the stages hypothesis holds for RFID technologies. Specifically, organizations were seen to sequentially progress through the Initiation, Experimentation, and Implementation stages. Over 80% of organizations, who had reached the Implementation stage of adoption, had gone through the Initiation and Experimentation stages as well. Additionally, the data showed that the antecedents exerted varying levels of influences on the three stages. Top management support strongly influenced all three stages; external pressure influenced the Initiation and Implementation stages, and organizational size influenced Experimentation and Implementation stages. The paper discusses several implications for research and practice. 相似文献
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A. Madhusudhana Rao R. Apoorva Usha Anand C. V. Anand G. Venu 《Indian journal of clinical biochemistry : IJCB》2012,27(3):253-258
End stage renal disease (ESRD) patients on hemodialysis (HD) have an increased oxidative stress, with a high risk of atherosclerosis and other co-morbid conditions. Recent studies have suggested that myeloperoxidase (MPO)—mediated oxidative stress may play a role in the pathogenesis of cardiovascular complications in dialysis patients. Furthermore, dialysis treatment ‘per se’ can aggravate oxidative stress. Hence this study was designed to determine whether HD leads to an alteration in the plasma levels of MPO and malondialdehyde (MDA), a marker of oxidative stress in ESRD patients on maintenance HD. To study the effect of HD, plasma MPO and MDA were determined before and after HD in forty ESRD patients (24 men and 16 women, age between 8 and 71 years, median being 40.5 years) on maintenance HD. Plasma MPO and MDA were assayed by spectrophotometric methods. Haematological and other biochemical parameters were obtained from patients’ case records. Plasma MPO and MDA levels were significantly higher after HD when compared with pre-dialysis levels (p < 0.05). There was no correlation between MPO and MDA (r = 0.184, p = 0.10) and other biochemical parameters (p > 0.05). However, there was a significant correlation between MPO and MDA with haemodialysis vintage (p < 0.05). In univariate regression analysis duration of HD (β = 1.470, p = 0.045, β = 0.388, p = 0.013), was independently associated with MPO and MDA. Although HD is indispensable for survival of patients with ESRD, it is fraught with undesirable side-effects, such as an increase in the plasma MPO and MDA levels. The elevated levels of MPO contribute to the increased oxidative stress as free radicals are produced by the reaction catalyzed by it. 相似文献
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Paraoxonase is an anti-oxidant enzyme, which circulates in the plasma, tightly bound to HDL. This enzyme is known to be synthesized
in the liver. This study was carried out in order to ascertain the diagnostic utility of this enzyme in acute liver disease.
Serum basal as well as salt (NaCl) stimulated paraoxonase was estimated in 50 patients with an established diagnosis of acute
liver disease and also in 50 healthy blood donors. Paraoxonase levels were significantly lower in patients as compared with
controls (P < 0.05). The ‘receiver operating characteristic’ plot showed that this enzyme has a high degree of sensitivity and specificity
for the diagnosis acute liver disease. Serum PON is likely to emerge as an additional test of liver function, as it encompasses
three different attributes of hepatic function namely, synthetic capacity, detoxication and secretory functions. 相似文献
89.
Krishnamurthy N Arumugasamy K Anand U Anand CV Aruna V Venu G 《Indian journal of clinical biochemistry : IJCB》2011,26(2):120-124
Cystatin C is an emerging parameter for the assessment of renal allograft function. The objective of the study was to compare
the efficacy of serum cystatin C (SCys) with the established parameter serum creatinine (SCr) in the assessment of renal function
in renal transplant recipients (RTR). The glomerular filtration rate (GFR) of 30 renal transplant patients and 29 control
subjects was determined using 99mTc Diethylene-triamine-penta-acetate (DTPA) method. SCr was measured using an automated Jaffe’s assay and SCys was measured
using latex particle enhanced turbidimetric immuno assay (PETIA). The modification of diet in renal disease (MDRD) formula
was used to calculate GFR from SCr, while the Le Bricon formula was used to derive GFR based on SCys. Statistical analysis
was performed using MedCalc software. SCr and SCys levels were significantly higher, while DTPA clearance was significantly
lower in RTR (P < 0.0001) when compared with controls. The correlation coefficient (r value) between calculated GFR based on MDRD method and DTPA clearance was 0.343 (P = 0.06) while the calculated GFR based on Le Bricon formula was 0.694 (P < 0.001). The results have shown that SCys is a better parameter than SCr in assessing renal function in RTR. The inclusion
of SCys as an additional parameter would certainly help in detection of even a marginal decline in renal function and also
in adjusting the dosage of immunosuppressive drugs. 相似文献
90.
Hans Anand Pant 《Zeitschrift für Erziehungswissenschaft》2013,16(1):71-79
National educational standards (NES) were released in Germany 2003/2004 as obligatory performance standards substantively and normatively defining an acceptable degree of proficiency. The NES describe tangible competencies in the form of can-do statements for core subjects to be acquired by students at the end of defined stages of schooling. To evaluate standards-based performances the Standing Conference of the Ministers of Education and Cultural Affairs of the Federal States in Germany (KMK) implemented a test-based monitoring system that comprised a centralized evaluation in a nationwide study sample comparing the German federal states (Ländervergleich), as well as state-wide testing schemes at the end of grade 3 and grade 8 linked to the NES. All test items were designed by didactic experts on the basis of domain specific competence models that were psychometrically evaluated. The potential practical benefit from competence testing is discussed for the various system levels of feedback (state, school, teacher, and student). It is argued that, in order to tap the full potential of standards-based performance feedback, it must be appropriately communicated to the target system level and should be accompanied by suitable measures of action support. 相似文献