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801.
The paper describes the edition, on computer output microfiche, of the supplement to the 1965 Union catalogue of foreign periodicals in Belgian and Luxemburgian libraries and documentation centers. The microfiches contain location information of 28,000 periodicals in 300 libraries and are edited in a rich typography. The paper discusses the coding of the bibliographic fields, the computer processing and formulates some forecasts for the near and further future. 相似文献
802.
Bhawana Nigam S. P. Joshi Seema Nagar Rajesh Chavan D. Pendharkar 《Indian journal of clinical biochemistry : IJCB》1996,11(2):124-128
The analysis of biochemical parameters in 162 patients with various neoplastic disorders along with 50 normal subjects showed significant rise in serum alkaline phosphatase and lactate dehydrogenase as compared to normal subjects. 21 patients with other monoclonal gammopathies which include infection and immunological diseases were also studied. Parameters such as serum calcium, uric acid, total protein, albumin and globulin were also analyzed in 42 (26%) cases of multiple myeloma, 27 (17%) cases of gastro-intestinal malignancies, 22 (14%) cases of urogenital malignancies, 11 (6%) cases of carcinoma breast, 4 (2%) cases of bone tumors, 21 (12%) cases of other monoclonal gammopathies, including 7 (4%) cases of infection and 14 (8%) cases of immunological diseases. The results indicate use of enzymes alkaline phosphatase and lactate dehydrogenase in neoplastic disorders. 相似文献
803.
Ivan Bradaric Athina P. Petropulu Konstantinos I. Diamantaras 《Journal of The Franklin Institute》2002,339(2):161-187
Higher-order statistics (HOS) are well known for their robustness to additive Gaussian noise and ability to preserve phase. HOS estimates, on the other hand, have been criticized for high complexity and the need for long data in order to maintain small variance. Since rank reduction offers a general principle for reduction of estimator variance and complexity, we consider the problem of designing low-rank estimators for HOS. We propose three methods for choosing the transformation matrix that reduces the mean-square error (MSE) associated with the low-rank HOS estimates. We also demonstrate the advantages of using low-rank third-order moment estimates for blind system estimation. Results indicate that the full rank MSE corresponding to some data length N can be attained by a low-rank estimator corresponding to a length significantly smaller than N. 相似文献
804.
Savita Singh Varun Malhotra K. P. Singh S. B. Sharma S. V. Madhu O. P. Tandon 《Indian journal of clinical biochemistry : IJCB》2001,16(2):216-220
Nineteen subjects of non-insulin dependent diabetes mellitus (NIDDM) between the age group of 30–60 yrs were studied to see
the effect of specific yoga asanas on fasting and postprandial blood glucose (FBG, PPG), serum malondialdehyde (MDA) and glycosylated
hemoglobin (HbA1) in addition to drug treatment and diet control. The duration of diabetes ranged from 1–10 years. Patients with renal, cardiac
and proliferative retinal diseases were excluded from the study. The same patients served as their own control. Subjects were
called in the morning to the cardio-respiratory laboratory and were given training by a yoga expert. Yoga asanas included
Suryanamskar, Tadasan, TriKonasan, Padmasan, Pranayam, Paschimottanasan, Ardhmatsyendrasan, Pavanmukthasan, Sarpasan and Shavasan.
The asanas were done every day for 40 days for 30–40 min. FBG, PPG, serum MDA and HbA1 were estimated before and after 40 days of yoga asanas regimen. Significant reduction was seen in FBG from 220 mg/dl to 162
mg/dl, PPG from 311 mg/dl to 255 mg/dl, MDA from 6 nmol/l to 3 nmol/l and HbA1, from 8.8% to 6.4%. Subjects felt better and were relieved of their stresses and had an improvement in their day to day performance.
The decrease was statistically significant (p<0.0001 for FBG and PPG, p<0.001 for MDA and for HbA1). 相似文献
805.
A. A. Momin M. P. Bankar G. M. Bhoite 《Indian journal of clinical biochemistry : IJCB》2016,31(3):286-293
Elevated plasma triglyceride and non-esterified fatty acid concentrations may cause insulin resistance and type 2 diabetes mellitus. Lipoprotein lipase (LPL) is a rate-determining enzyme in lipid metabolism. A variant in the LPL gene has been identified which alters the penultimate amino acid Serine at 447 to a stop codon (S447X), and results in a truncated LPL molecule lacking the C-terminal dipeptide Ser–Gly. The present study was designed to evaluate the frequency of S447X variant in the LPL gene and its effect on the lipid and lipoprotein levels in type 2 diabetic subjects. The genotype frequency distributions of type 2 diabetes patients and controls were in Hardy–Weinberg equilibrium. Comparison of the genotype and allelic frequencies of S447X in subjects with type 2 diabetics compared to controls demonstrated no significant difference. In subjects with type 2 diabetics having hypertriglyceridemia (TG ≥ 150 mg/dl) compared to diabetics with TG level <150 mg/dl, significant difference in genotype frequency was found among these groups, while allelic frequency of X was significantly differed. Logistic regression analysis showed the negative association of LPL S447X variant with TG and VLDL cholesterol, while no association with total cholesterol, HDL cholesterol and LDL cholesterol was found. The lipid levels except for HDL cholesterol were found to be significantly lower in carriers for S447X than wild type in diabetes group. The decreased level of TG and TG rich lipoprotein in subjects with SNP S447X in LPL, predicts anti-atherogenic activity of carriers for S447X variant in general population as well as type 2 diabetic patients. 相似文献
806.
807.
Artificial Life (ALife) has two goals. One attempts to describe fundamental qualities of living systems through agent based
computer models. And the second studies whether or not we can artificially create living things in computational mediums that
can be realized either, virtually in software, or through biotechnology. The study of ALife has recently branched into two
further subdivisions, one is “dry” ALife, which is the study of living systems “in silico” through the use of computer simulations,
and the other is “wet” ALife that uses biological material to realize what has only been simulated on computers, effectively
wet ALife uses biological material as a kind of computer. This is challenging to the field of computer ethics as it points
towards a future in which computer and bioethics might have shared concerns. The emerging studies into wet ALife are likely
to provide strong empirical evidence for ALife’s most challenging hypothesis: that life is a certain set of computable functions
that can be duplicated in any medium. I believe this will propel ALife into the midst of the mother of all cultural battles
that has been gathering around the emergence of biotechnology. Philosophers need to pay close attention to this debate and
can serve a vital role in clarifying and resolving the dispute. But even if ALife is merely a computer modeling technique
that sheds light on living systems, it still has a number of significant ethical implications such as its use in the modeling
of moral and ethical systems, as well as in the creation of artificial moral agents. 相似文献
808.
Steven J. Sackett James M. Kelley Peter P. Gillis 《Journal of The Franklin Institute》1977,304(1):47-63
Using our constitutive theory for polycrystalline plasticity, we have calculated characteristic yield conditions for several sample materials in which the dependence of the dislocation velocity on stress is given by an empirical power function. The shape of the yield surfaces for these materials varies resembling that of von Mises when the stress exponent is small and that of Tresca when the exponent is large. Additional examples illustrate the ability of the proposed theory to model such phenomena as the development of anisotropy during plastic deformation, material hardening and softening, the occurrence of upper and lower yield points, and a Bauschinger effect. 相似文献
809.
Study on arsenic level in public water supply of Delhi using hydride generator accessory coupled with atomic absorption spectrophotometer 总被引:1,自引:0,他引:1
Sanjeev Lalwani T. D. Dogra D. N. Bhardwaj R. K. Sharma O. P. Murty 《Indian journal of clinical biochemistry : IJCB》2006,21(1):70-76
Exposure to arsenic has been associated with several health hazards. Worldwide the main reason for chronic human intoxication
with arsenic is intake of contaminated drinking water. Air acetylene type of atomic absorption spectrophotometer in combination
with hydride generator accessory was used to analyze arsenic level in 25 water samples collected from 25 booster pumping stations
and 313 water samples collected from tap water supply of 62 areas of Delhi. Results were analyzed using SPSS and Barlett’s
Chi Square Test. Mean arsenic level detected in water samples collected from booster pumping stations was 0.00976 ppm (Range
0.000–0.017 ppm, Standard Deviation 0.006 and Standard error of Mean 0.00118). Maximum arsenic level (0.017 ppm) was found
in water samples of booster pumping stations of Mehrauli, Punjabi Bagh and Ramjas Road. Mean arsenic level detected in samples
collected from tap water supply was 0.013 ppm (Range 0–0.0430 ppm, Standard Deviation 0.00911 and Standard error of Mean 0.000515).
In water samples of 42 areas arsenic level detected was exceeding WHO/EPA permissible limit of 0.01 ppm (10 ppb). The mean
arsenic level detected in water samples of booster pumping station was within WHO/EPA permissible limit while mean arsenic
level detected in tap water samples was marginally higher. Mixing of ground water and contamination through broken or leaking
channel could be the possible reason of higher arsenic level in tap water. Continuous monitoring of quality of drinking water
is required particularly in view of water contamination caused by industrial waste and uncontrolled ground water extraction. 相似文献
810.
Ajay Kumar T. A. Venkita Subramanian Usha P. Sharma 《Indian journal of clinical biochemistry : IJCB》1992,7(2):165-168
Protein fraction termed P2 was obtained from sonicates of Mycobacterium smegmatis, subjected to ammonium sulphate precipitation. P2 fraction was further fractionated into 4 fractions (PeakI-IV) by DEAE cellulose ion-exchange chromatography. ELISA was performed
on the sera of 104 tuberculous cases and 62 controls, using P2 fractions Peak I as test antigens. Though the mean ELISA values in tuberculous cases were higher than the controls, no statistically
significant difference was found between the two. Antigens P2, Peak I and IV were tested on Western blots with pooled sera from tuberculous cases as well as controls. P2 fraction, Peak-I and IV were separated on PAGE-SDS, electroblotted onto nitrocellulose Sheets and the blots were subjected
to ELISA. Peak IV appeared as a single band (M.W. 55,000). P2 fraction exhibited some discriminatory bands on development of blots. 相似文献