电路综合实验改进模式的探索与实现

电路综合实验是电子信息类专业必修的一门专业基础实验课,在课程衔接上起着承上启下的重要作用.分析了通信专业学生不同学习阶段的专业知识层次特点,提出用模块化的设计理念,并以此理念为指导,以数字基带传输系统为例,利用FPGA(field programmable gate array)技术,将软件仿真和硬件结合起来,解决了数字基带传输系统设计环节中几个关键的技术问题,开发了各个模块级实验以及整个系统级实验,实现了不同阶段课程内容的有效衔接和融合,解决了学生知识背景低和实验内容层次高的矛盾.     

独立学院大学英语目标定位及实现途径--以温州大学城市学院为例

大学英语作为各高校都开设的一门公共基础课程,历来受到各界的重视。而对于独立学院而言,大学英语课程体系的准确定位,关系到整个课程体系的发展方向。本文以温州大学城市学院为例,旨在探讨在当前大学英语转型的新形势下,独立学院应如何确定大学英语的目标定位,进而对此定位的实现途径从课程体系设置、教学模式方法选择和评估手段采用等方面进行讨论。     

Effect of Hemodialysis on Plasma Myeloperoxidase Activity in End Stage Renal Disease Patients

End stage renal disease (ESRD) patients on hemodialysis (HD) have an increased oxidative stress, with a high risk of atherosclerosis and other co-morbid conditions. Recent studies have suggested that myeloperoxidase (MPO)—mediated oxidative stress may play a role in the pathogenesis of cardiovascular complications in dialysis patients. Furthermore, dialysis treatment ‘per se’ can aggravate oxidative stress. Hence this study was designed to determine whether HD leads to an alteration in the plasma levels of MPO and malondialdehyde (MDA), a marker of oxidative stress in ESRD patients on maintenance HD. To study the effect of HD, plasma MPO and MDA were determined before and after HD in forty ESRD patients (24 men and 16 women, age between 8 and 71 years, median being 40.5 years) on maintenance HD. Plasma MPO and MDA were assayed by spectrophotometric methods. Haematological and other biochemical parameters were obtained from patients’ case records. Plasma MPO and MDA levels were significantly higher after HD when compared with pre-dialysis levels (p < 0.05). There was no correlation between MPO and MDA (r = 0.184, p = 0.10) and other biochemical parameters (p > 0.05). However, there was a significant correlation between MPO and MDA with haemodialysis vintage (p < 0.05). In univariate regression analysis duration of HD (β = 1.470, p = 0.045, β = 0.388, p = 0.013), was independently associated with MPO and MDA. Although HD is indispensable for survival of patients with ESRD, it is fraught with undesirable side-effects, such as an increase in the plasma MPO and MDA levels. The elevated levels of MPO contribute to the increased oxidative stress as free radicals are produced by the reaction catalyzed by it.     

学术自由与学术责任——大学学术发展的价值协调

学术自由是大学理念中一个最基本的学术价值观,它不仅是学术研究者的一种权利,而且体现为大学内部所特有的独立品格和精神。自17世纪末期近代大学形成以来,学术自由的理念不断强化,内涵不断丰富,逐步成为大学之所以为大学的基础、动力源和基本理念。三百年来,一方面学术自由使大学保持着宽松的研究氛围,传承文明,追求真理;另一方面,在所谓“学术自由”的保护伞下,一些研究人员却暗中接受政府巨额资金,为政府不光彩的行动出谋划策,学术腐败和对学生不负责任的行为也时有发生。对曾经寄予厚望、充满理想色彩的学术圣地——“大学”,人们已颇多…     

中小学校园性侵害预防机制的构建

近年来,中小学校园性侵害频频发生,已引起社会各界的强烈反响。教师对学生实施的性侵害,对教育这一神圣职业产生了极为严重的破坏性冲击。教师素质的提高,教师职业道德的重塑,成为教育改革的新课题。根据校园性侵害的特点,构建校园性侵害预防和控制的有效机制,则是解决这一问题的关键。     

Cancer in south Karnataka and its paradoxical relation to diabetes mellitus

The present work identifies a high incidence of oral cancer in south Karnataka. The primary reason for this could be due to extensive addiction to tobacco alone or tobacco and alcohol in most of these patients. The next in intensity was cancer of the breast and cervix among the cancer patients surveyed in south Karnataka. Majority of these patients had no specific addiction and the exact reason for this high incidence remains unclear. Only a small percentage of patients exhibited other types of organ related cancer. It has been reported that the incidence percentage of diabetes mellitus and cancer in India, parallel each other. However, we observed a low incidence of diabetes mellitus patients also having cancer in south Karnataka. Though the exact reason for this remains unclear an attempt has been made here to explain this phenomenon, hypothetically using information in literature, which suggests a suppression of cellular regenerative activity by sugar and sugar phosphates. Cellular regenerative activity is well known to be a prerequisite for cancer.     

Studies on the antiperoxide and antihaemolytic action of polyamines using human erythrocytes

Blood RBC's were used to study the role of polyamines, putrescine, spermidine and spermine individually as antioxidants against the peroxidative action of H₂O₂ which leads to haemolysis of erythrocytes. Results indicated that putrescine did not act as antioxidant at all concentrations used in our studies. However, spermidine and spermine suppressed peroxidative changes in RBC's due to the action of H₂O₂ and this suppression was greater with higher concentration of these individual polyamines used, separately. Further, all the three polyamines decreased haemolysis of erythrocytes at all concentrations studied. The action of putrescine to suppress haemolysis of RBC's without showing antioxidant property hypothetically suggests that these properties of respective polyamines may have independent mechanism of action.     

Radioprotective effects of ocimum flavonoids on leukocyte oxidants and antioxidants in oral cancer

Oxidants (NADPH oxidase and myeloperoxidase) and antioxidants (GSH,GSH peroxidase, SOD and glucose 6 phosphate dehydrogenase, that provides NADPH for antioxidants) were assayed in the neutrophils from oral cancer patients, in three stages viz, baseline samples,15 days after radiation and 30 days following radiation. These samples were obtained from 2 groups of patients. Group A that received radiation alone and Group B that received radiation and ocimum flavonoids,a radioprotector. The results showed a significant fall in the SOD levels in the second follow up of group B.Glucose 6 phosphate dehydrogenase showed significant increase only in the first follow up of patients who received Ocimum flavonoids. Except for these findings all other parameters remained statistically nonsignificant.     

基于教师生活史研究的职业教育学硕士生导师专业发展研究综述

对教师生活史与职业教育学硕士生导师专业发展关系的研究目前还是空白。国内外关于教师生活史、教师专业发展及其之间的关系研究为此提供了很好的基础。这一领域研究与当前职业教育学硕士研究生教育的数量扩充、质量提升、可持续发展及国际化的要求相适应,是职业教育学学科建设及导师知识结构调整的需要。从教师生活史的角度,职业教育学硕士生导师的专业发展体现在学术专业素质和道德人格素质两方面。