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71.
Kushalnagar P Krull K Hannay J Mehta P Caudle S Oghalai J 《Journal of deaf studies and deaf education》2007,12(3):335-349
Cognitive ability and behavioral adaptability are distinct, yet related, constructs that can impact childhood development. Both are often reduced in deaf children of hearing parents who do not provide sufficient language and communication access. Additionally, parental depression is commonly observed due to parent-child communication difficulties that can lead to parents' feelings of inadequacy and frustration. We sought to assess whether adaptive behavior in deaf children was associated with nonverbal intelligence and parental depression. Parents of precochlear implant patients seen for neuropsychological assessment were administered the Parenting Stress Index and Vineland Behavior Adaptive Scales to obtain measures of parental distress and child's behavioral adaptability. Precochlear implant patients' cognitive functioning was assessed via the Mullen Scales of Early Learning or the Leiter International Performance Scale-Revised, depending on the child's age at the time of testing. Regardless of age or neurological status, the deaf child's adaptive behavior consistently showed a strong relationship with intelligence. Moderate correlation between parental depression and the child's adaptive behavior was observed only in the younger group. The relationship between parental depression and communication subscale was moderated by intelligence for deaf children without neurological complications. The findings provide important implications for promoting family-centered interventions with early communication and language development. 相似文献
72.
Because the feedback children and adolescents receive is important to their development, 2 experimental studies were designed to examine children's (M = 12 years) and adolescents' (M = 17 years) active selection of the quality of feedback they wish to receive. In both studies evidence emerged that participants' self-perceptions influence their feedback seeking. Participants with positive self-perceptions sought more positive feedback than participants with negative self-perceptions and sought more positive feedback than expected by chance. Participants with negative self-perceptions lacked this tendency to seek positive feedback and sometimes sought less positive feedback than expected by chance. As expected, depression and attachment-related measures were also associated with participants' feedback seeking. Contributions of feedback-seeking patterns to stability and change in children's and adolescents' development are discussed. 相似文献
73.
D. Krishnaveni Amar Chand Bhayal K. Sri Manjari A. Vidyasagar M. Uma Devi M. Ramanna A. Jyothy Pratibha Nallari A. Venkateshwari 《Indian journal of clinical biochemistry : IJCB》2012,27(3):259-264
Matrix metalloproteinase-9 (gelatinase B) plays a key role in cancer invasion and metastasis by degrading the extracellular matrix and basement membrane barriers. A cytosine (C) > thymidine (T) single nucleotide polymorphism (SNP) at position −1562 in the MMP-9 promoter is reported to influence the expression of the gene. Genotyping of MMP-9 −1562 C→T promoter polymorphism in 140 gastric cancer patients and 132 healthy control subjects was carried out in order to evaluate its association with progression and development of gastric cancer. The SNP was genotyped by tetra-primer amplification refractory mutation system-polymerase chain reaction followed by agarose gel electrophoresis. Statistical methods were adopted to test for the significance of the results. Risk factor profile of the patients revealed age above 50 years, smoking, alcoholism as the factors associated with the disease. The distribution of genotype frequencies in gastric cancer patients were 28.7 % of CC, 45.5 % of CT and 25.7 % of TT, whereas in control subjects 31.8 % of CC, 53.03 % of CT and 15.15 % of TT, respectively. The allelic frequencies were 51.51 % of C and 48.48 % of T in patient group and 58.33 % of C and 41.66 % of T in controls respectively. The present study shows the possible association of epidemiological risk factors with gastric cancer. There is an increased frequency of T allele in the disease compared to control subjects. However, there is no association of the MMP-9 −1562 C→T promoter polymorphism in the development of gastric cancer. 相似文献
74.
75.
Michael D. Mehta Eric Darier 《The Information Society》1998,14(2):107-116
Current interest in the electronic highway is the latest expression of a technotopia that is about to resolutely tilt Western contemporary society into postmodernity, or at least into virtual modernity. The enthusiasm for the electronic highway is already having numerous 'power effects' (Burchell et al., 1991). One of these effects is to radically intensify modern forms of power in a new regime we call electronic governmentality. This article examines these effects by drawing on examples from the Internet, and demonstrates how this communication and information infrastructure challenges some of our most tightly held beliefs about progress, technology, and power. 相似文献
76.
In two experiments, participants acquired one of two target configural discriminations (a biconditional or negative patterning
discrimination) in a predictive learning task. In Experiment 1, participants were pretrained with either a configural or an
elemental discrimination; in Experiment 2, they were pretrained with a configural discrimination, an elemental discrimination,
or a control discrimination that was not expected to bias them toward elemental or configural processing. In both experiments,
acquisition of the target configural discriminations was faster after configural pretraining than after elemental pretraining.
In addition, the negative patterning discrimination was acquired faster than the biconditional discrimination. Finally, the
results of Experiment 2 were more consistent with the notion that elemental pretraining hindered acquisition of the target
discriminations than with the notion that configural pretraining enhanced their acquisition. Implications of these findings
are discussed. 相似文献
77.
Ashwini Kumar H. S. Batra Mithu Banerjee S. Bandyopadhyay T. K. Saha Pratibha Misra Vivek Ambade 《Indian journal of clinical biochemistry : IJCB》2017,32(3):343-346
Thalassemia is a congenital hemolytic disease which is treated by repeated blood transfusion. Chronic iron overload is currently considered to be the primary cause of mortality in β-thalassemia, mainly due to the induction of left-sided cardiac failure. Iron overload results from a number of mechanisms associated with the disease itself. In addition to chronic iron overload thalassemic patients are more prone for procoagulant status which in turn lead to clinical thrombotic events. The hypercoagulable state in thalassemia is due to multiple elements, a combination of which is often the drive behind a clinical thromboembolic events. PAI-1 study was done in thalassemia major patients receiving multiple blood transfusion as a marker for procoagulant status. Total of 30 thalassemic patients on repeated blood transfusion was included in the study and total of 30 healthy age and sex matched controls were included in the study. It was also found that there was significant differences between cases and controls. The mean level of PAI 1 in controls was 3047 ± 414 pg/ml, the value in cases was 3683 ± 358 pg/ml. The level was significantly increased (p < 0.05) in the cases compared to controls. PAI-1 levels were also compared with the total number of blood transfusion which correlates well. 相似文献
78.
K. N. Dave B. N. Dave F. R. Billimoria M. N. Mehta N. K. Hase 《Indian journal of clinical biochemistry : IJCB》1990,5(2):135-138
Total acetylcholinesterase (AChE) activity was estimated in cerebrospinal fluid (CSF) using colorimetric method in 64 cases
with tuberculous meningitis, (TBM) (n=64), pyogenic meningitis (PM) (n=60) and in controls (n=39) of paediatric age group.
Mean CSF—AChE values of both TBM and PM were significantly higher when compared with controls (p<0.001) but no significant
change between TBM and PM was observed (p<0.01). It is suggested that inflammation of meninges due to the infection may attribute
to a change in the function of blood brain barrier (BBB) causing higher CSF—AChE values in these diseases. 相似文献