Modeling the development of written language

Alternative models of the structure of individual and developmental differences of written composition and handwriting fluency were tested using confirmatory factor analysis of writing samples provided by first- and fourth-grade students. For both groups, a five-factor model provided the best fit to the data. Four of the factors represented aspects of written composition: macro-organization (use of top sentence and number and ordering of ideas), productivity (number and diversity of words used), complexity (mean length of T-unit and syntactic density), and spelling and punctuation. The fifth factor represented handwriting fluency. Handwriting fluency was correlated with written composition factors at both grades. The magnitude of developmental differences between first grade and fourth grade expressed as effect sizes varied for variables representing the five constructs: large effect sizes were found for productivity and handwriting fluency variables; moderate effect sizes were found for complexity and macro-organization variables; and minimal effect sizes were found for spelling and punctuation variables.     

向着星辰与大海——Minecraft Genshin Nature模组介绍

<正>今天的故事,要从国庆假期前某位热心小读者发来的一封邮件讲起——标题:做《原神》攻略行吗正文:小约小约,你能不能介绍一下《原神》呀,我很想看看。求求你了!小约忍不住挠了挠头。《原神》是米哈游开发的一款大型开放世界冒险游戏,从这两年的风靡程度来看,它已经算得上是一部现象级的游戏了。不过,由于《原神》属于网络游戏,小读者每周可以玩三小时,同时考虑到游戏内容之多,要在这里介绍还是有一些困难的。话又说回来,小约也不是第一次收到类似内容的邮件了,最终决定以另外一种形式满足这位小读者的要求——今天,     

Allometric scaling of Wingate anaerobic powertest scores in women

In this study, we developed allometric exponents for scaling Wingate anaerobic test (WAnT) power data that are effective in controlling for body mass (BM) and lean body mass (LBM) and established a normative WAnT data set for college-age women. One hundred women completed a standard WAnT Allometric exponents and percentile ranks for peak (PP) and mean power (MP) were established. Allometric exponents were applied to WAnT scores for an independent sample (n=31) to assess external validity. PP and MP were 477.0 W (SD = 80.0) and 372.6 W (SD = 61.5), respectively. Allometrice exponents for PP and MP scaled for BM were b = 0.92 and b = 0.76, respectively, and for LBM they were b = 0.93 and b = 0.91, respectively. In the independent sample, these exponents produced correlations between allometrically scaled PP and MP and BM of r = -.02 and r = .02, respectively. Correlations between allometrically scaled PP and MP and LBM were r = .004 and r = -.02, respectively. The allometric exponents were effective in partialing out the effect of BM for PP and MP and demonstrated acceptable levels of external validity when applied to an independent sample. The allometric exponents and normative values provide a useful tool for comparing WAnT scores in college-age women without the confounding effects of BM or LBM.     

Biochip∕laser cell deposition system to assess polarized axonal growth from single neurons and neuron∕glia pairs in microchannels with novel asymmetrical geometries

Axon path-finding plays an important role in normal and pathogenic brain development as well as in neurological regenerative medicine. In both scenarios, axonal growth is influenced by the microenvironment including the soluble molecules and contact-mediated signaling from guiding cells and cellular matrix. Microfluidic devices are a powerful tool for creating a microenvironment at the single cell level. In this paper, an asymmetrical-channel-based biochip, which can be later incorporated into microfluidic devices for neuronal network study, was developed to investigate geometric as well as supporting cell control of polarized axonal growth in forming a defined neuronal circuitry. A laser cell deposition system was used to place single cells, including neuron-glia pairs, into specific microwells of the device, enabling axonal growth without the influence of cytophilic∕phobic surface patterns. Phase microscopy showed that a novel "snag" channel structure influenced axonal growth in the intended direction 4:1 over the opposite direction. In heterotypic experiments, glial cell influence over the axonal growth path was observed with time-lapse microscopy. Thus, it is shown that single cell and heterotypic neuronal path-finding models can be developed in laser patterned biochips.