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The Indian Council of Social Science Research (ICSSR) was established for development of social science research in India. It provides grants to 27 research institutes and six regional centers in India. These institutes have established close links with scholars in the region through activities such as seminars, workshops, training, and consultancy programs. Some of the institutes are closely associated with national and state level planning development agencies and have thereby strengthened the links between research and policy-making. The present study includes 22 institute libraries and three regional libraries in different Indian states. The study analyses their annual acquisition of books; periodicals; CD-ROMs; annual budgets; computerization; hardware and software; Internet; library network; and interlibrary loan and photocopy facilities available in these libraries. Digitization provides a solution to traditional library problems such as conservation, preservation, multimedia documents, and remote access to information, collection, and storage space. ICSSR institute libraries are replacing conventional storage and network systems with digital systems. The progress is a bit slow. Only a few ICSSR institute libraries are subscribing to electronic journals and having electronic documents. ICSSR institute libraries have started computerized operations and are making vigorous attempts to have digitized collections. However, these libraries are required to understand literature growth and use patterns in the social sciences.  相似文献   
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Vitiligo is an idiopathic, acquired, circumscribed, hypomelanotic skin disorder, characterized by milky white patches of different sizes and shapes. It is due to the destruction of melanocytes resulting in the absence of pigment production of the skin and mucosal surfaces. Oxidative stress has been implicated in pathophysiology of vitiligo. To study the activity of blood Superoxide dismutase (SOD) and Glutathione peroxidase (GPx) in vitiligo patients. A case–control study was conducted in which 100 patients were enrolled after written consent. 50 cases were of active vitiligo and 50 served as control (25 healthy control and 25 with stable vitiligo). SOD—In our study, among the active vitiligo cases 90% had high level of SOD and 10% had normal level of SOD. Among the stable vitiligo controls, 92% had normal level of SOD and 8% had low levels of SOD.The difference between active vitiligo cases and stable vitiligo control as well as with healthy control was statistically significant (P value < 0.05). GPx—Among the active vitiligo cases 74% had normal GPx levels, 22% had low and only 4% had high levels of GPx. Among the stable vitiligo controls, 64% had normal GPx levels, 16% had low, and 20% had high levels of GPx. The difference between active vitiligo cases and stable vitiligo control as well as with healthy control was statistically not significant (P value > 0.05). Our study shows that oxidative stress is involved in the pathophysiology of vitiligo, as indicated by the high levels of serum superoxide dismutase activity.  相似文献   
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The increasing incidence of obesity, leading to metabolic complications is now recognized as a major public-health problem. Insulin resistance is a central abnormality of the metabolic syndrome, or syndrome X, originally hypothesized by Reaven Insulin resistance is more strongly linked to intra abdominal fat than to fat in other depots. Adipose tissue secretes numerous factors (adipokines) known to markedly influence lipid and glucose/insulin metabolism, oxidative stress, and cardiovascular integrity. Some of these adipokines have been shown to directly or indirectly affect insulin sensitivity through modulation of insulin signaling and the molecules involved in glucose and lipid metabolism. A pilot study was conducted with 80 healthy subjects who were non diabetic, non hypertensive and having no family history of hypertension, the aim was to evaluate the correlation of adiponectin and leptin levels with obesity and insulin resistance markers in healthy north Indian adult population. Serum leptin, adiponectin and insulin was estimated by sandwich ELISA method. In our study, Leptin correlated significantly with BMI (P value of 0.0000), WC (P value = 0.007), and HC (P value = 0.000). leptin showed significant positive correlation with fasting insulin (P value 0.002), post prandial insulin (P value = 0.000) and HOMA-IR (P value = 0.002). Adiponectin showed significant positive correlation with triglycerides (P value = 0.038), strong negative correlation with HDL-cholesterol (P value = 0.017). Serum concentrations of leptin are associated with central body fat distribution. Insulin resistance and adiponectin is associated with dyslipidemia and these all disorders may ultimately lead to metabolic syndrome.  相似文献   
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The introduction of a social software blog space called the Trading Room in an undergraduate finance unit generated a great deal of activity to support student learning. A subsequent evaluation of this innovation, viewed through the lens of Activity Theory, demonstrated that students perceived high value in the opportunity it provided for them to reaffirm theories, obtain individualised feedback and benchmark their work against others. While assessment is generally seen as the carrot and the stick of learning; students in the study reported that they would still participate in reading and posting to the Trading Room even if there was no assessment requirement. Students did not see any value in the environment as a purely social space, reporting that they saw it primarily as a professional educational community. It would appear that just as there are different communities in the real world social space, there are also different types of communities in the online space.  相似文献   
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The Indian Council of Social Science Research (ICSSR) was established for development of social science research in India. It provides grants to 27 research institutes and six regional centers in India. These institutes have established close links with scholars in the region through activities such as seminars, workshops, training, and consultancy programs. Some of the institutes are closely associated with national and state level planning development agencies and have thereby strengthened the links between research and policy-making. The present study includes 22 institute libraries and three regional libraries in different Indian states. The study analyses their annual acquisition of books; periodicals; CD-ROMs; annual budgets; computerization; hardware and software; Internet; library network; and interlibrary loan and photocopy facilities available in these libraries. Digitization provides a solution to traditional library problems such as conservation, preservation, multimedia documents, and remote access to information, collection, and storage space. ICSSR institute libraries are replacing conventional storage and network systems with digital systems. The progress is a bit slow. Only a few ICSSR institute libraries are subscribing to electronic journals and having electronic documents. ICSSR institute libraries have started computerized operations and are making vigorous attempts to have digitized collections. However, these libraries are required to understand literature growth and use patterns in the social sciences.  相似文献   
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This article examines the negotiation of organizational tensions by purpose-driven consultancies, for-profit firms also motivated by social change agendas in their implementation of organizational development for corporate clients. Using two case studies – APCom training ethical corporate leaders, and GreenD communicating environmental sustainability programs – we trace how such consultancies negotiate these tensions, and how their underlying purpose might accordingly transform. Our multi-case study suggests two broad tensions related to purpose and impact that are experienced in context-specific ways by the consultancies. Although members sought to frame these tensions in positive ways, as complementary dialectics or contradicting the dominant capitalist system, they were also at risk of devolving into more paradoxical contradictions and even debilitating double binds, without sustained discussion to ‘repurpose’ the firms. We close by discussing theoretical and practical implications for purpose-driven consultancies, given that their pursuit of social change is often at odds with the status quo.  相似文献   
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