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551.
Rakesh D. Raut Bhaskar B. Gardas Manoj Kumar Jha Pragati Priyadarshinee 《The Journal of High Technology Management Research》2017,28(2):125-141
For cutting down cost and improving the efficiency of enterprises, adoption of innovations in ICT especially in cloud computing applications is the need of the time in the highly competitive global environment. It has been noted that generally, the Indian MSMEs are not utilizing the CC applications for the promotion of their business activities and are not availing their benefits. Hence, in the present investigation, the critical success factors (CSFs) for cloud computing adoption (CCA) in the Indian micro, small and medium enterprises (MSMEs) are identified through an exhaustive literature review and expert opinions. The association between the identified factors is established by employing an interpretive structural modeling methodology that is a multi-criteria decision making (MCDM) approach. Later, the MICMAC analysis is carried out for identifying the factors having high influential power. The results of the study revealed that a CSF namely ‘previous technological experience’ is the most significant factor having the highest driving power. The findings of this research are intended to guide cloud service providers, enterprise managers, and governmental bodies in formulating the strategies and policies for effective implementation of cloud computing facilities and harness the benefits of the same. This study makes a significant contribution to the knowledge base of CC adoption for future research in the subject field. 相似文献
552.
Post-secondary educational attainment is an increasingly important prerequisite to many valued outcomes. This paper examines the association of racially-specific high school course of study with student’s postsecondary educational attainment using ELS 2002–2012 and a comprehensive measure of course intensity derived from students’ patterns of course-taking. Results support a partial presence of racially-specific association of high school course of study. We also find that only Asian-American and American Indian/Alaskan Native students in the middle course intensity and Asian-American students in high course intensity ranges are more likely to obtain at least a 4-year college degree than same-race students in the low course intensity group. However, the same pattern is not evident for White, African-American, multi-racial, and Hispanic students, indicating that they do not experience the same benefit from academically rigorous courses of study. Also, educational expectations do not mediate the relationships among race, course of study, and postsecondary educational trajectory differently for students of different racial groups, i.e., they do not play a larger role in mediating the relationship between course of study and postsecondary educational trajectory for White students. 相似文献
553.
Ananth N. Rao J. Kavitha Minakshi Koch V. Suresh Kumar 《Indian journal of clinical biochemistry : IJCB》2009,24(3):215-222
Inherited metabolic disorders are a heterogeneous group of genetic conditions mostly occurring in childhood. They are individually
rare but collectively numerous, causing substantial morbidity and mortality. We have retrospectively reviewed a total of eight
hundred and sixty nine cases with different age groups that had been referred from several diagnostic centers and hospitals
of India to the Department of Metabolism in Narayana Hrudayalaya, as cases suspected with inborn errors of metabolism. Advanced
techniques applied were to diagnose the disorders of inborn errors of metabolism. Data analyzed indicates occurrence of several
metabolic disorders in our population. The need to screen for an inborn error of metabolism arises out of the fact that most
cases take to irreversible effects as time progress. Emphasis has to be laid on early detection and prompt management, which
could help in alleviating symptoms and preventing complications and consequent incapacitation. 相似文献
554.
Rizwan Ahmad Anil K. Tripathi Payal Tripathi Ranjana Singh Sushma Singh Raj K. Singh 《Indian journal of clinical biochemistry : IJCB》2008,23(4):328-333
Chronic myeloid leukemia is a myeloproliferative disorder with a unique rearrangement, the Philadelphia chromosome. Oxidative
stress, a pervasive condition of an increased number of reactive oxygen species, is now recognized to be prominent feature
of various diseases and their progression. Thus antioxidants, which control the oxidative stress state, represent a major
line of defense regulating overall true state of health. The relationship between antioxidants status and levels of well-known
markers of oxidative stress that are measured as lipid peroxides and oxidized proteins reflect better health indices and postures.
The aim of this study was to evaluate the role of oxidative stress in pathophysiology of Chronic myeloid leukemia by measuring
the circulating plasma lipid peroxide levels in terms of malonyldialdehyde, total lipid hydroperoxide and oxidized proteins
as protein carbonyl whereas antioxidant status were estimated in terms of reduced glutathione and total thiol in plasma of
Chronic myeloid leukemia patients. The present study included 47 Chronic myeloid leukemia patients and 20 age-and sex-matched
healthy subjects. Out of 47 Chronic myeloid leukemia patients, 31 were in chronic phase (CML-CP) and 16 in accelerated phase
(CML-AP). The median age of Chronic myeloid leukemia patients was 33 years and that of controls was 32 years. Oxidative stress
and antioxidant status in plasma were evaluated by spectrophotometric procedures. There was a significant increase (p<0.05)
in plasma malonyldialdehyde, total lipid hydroperoxide and protein carbonyl levels in Chronic myeloid leukemia patients as
compared to healthy subjects. Our results also showed that plasma malonyldialdehyde and protein carbonyl levels were markedly
elevated (p<0.05) in both chronic phase (CML-CP) and accelerated phase (CML-AP) as compared to healthy volunteers. Antioxidant
status was found to be significantly decreased (p<0.05) in Chronic myeloid leukemia patients and its phases as compared to
healthy participants. It could be concluded that oxidative stress may be associated with the pathophysiology of Chronic myeloid
leukemia. 相似文献
555.
Prashant Kumar Rai Dolly Jaiswal Devendra K. Rai Bechan Sharma Geeta Watal 《Indian journal of clinical biochemistry : IJCB》2008,23(4):387-390
In rats with streptozotocin induced severe diabetes mellitus, aqueous extract of Trichosanthes dioica fruits at a dose of
1000mg/kg body weight daily once for 28 days reduced the levels of fasting blood glucose, postprandial glucose, asparate amino
transferase, alanine amino transferase, alkaline phosphatase, creatinine, urine sugar and urine protein where as total protein
and body weight was increased. No toxic effect was observed during LD50. Our study suggests that further detailed toxicity
studies and mechanism of action of T. dioica would be useful for undertaking human trials. 相似文献
556.
Sunil Kumar Gupta R. C. Gupta Kapil Gupta H. P. Trivedi 《Indian journal of clinical biochemistry : IJCB》2008,23(2):176-180
This study was conducted to find out the possible underlying mechanism of various manifestation of fluorosis, a disease caused
by excess ingestion of fluoride. For this the fluoride belt of Jaipur district was selected. The parameters selected were
serum Parathyroid hormone, the levels of which are directly affected by fluoride intake. The levels of serum seromucoid, serum
and leucocyte ascorbic acid, serum sialic acid (SSA) reflects ground substance metabolism. The study was conducted on two
hundred children, selected from four areas (50 from each area) consuming water containing 2.4, 4.6, 5.6 and 13.6 mg/l of fluoride.
Drinking water fluoride and serum fluoride were measured by Ion selective electrode method. Serum parathyroid by RIA and all
other parameters were measured spectrophotometrically. The results revealed an increase in levels of fluoride, parathyroid
hormone and seromucoid in serum with increasing water fluoride concentrations. Serum Calcium and serum ascorbic acid were
found in normal range, how ever leucocyte ascorbic acid were decreased. A high positive correlation among fluoride concentration
in drinking water and serum parathyroid hormone (r=0.967), and, serum parathyroid hormone and serum seromucoid concentration
(r=0.935) was also observed The results indicated that secondary hyperparathyroidism due to hypocalcemic stress caused by
excess fluoride ingestion disturbs normal metabolism of ground substance in calcified tissues of the body reflected as altered
levels of the components of ground substance in the serum. 相似文献
557.
Rajinder K. Dhamija Sarika Arora P. Gaba M. Jais A. Kaintura M. Kumar J. Bhattacharjee 《Indian journal of clinical biochemistry : IJCB》2008,23(2):136-143
Stroke is the third leading cause of death and foremost cause of disability. Based on studies in CAD patients, a focus has
been shifted on genetic and inflammatory markers as risk factors for stroke besides deranged lipid profile. The present study
was aimed to ascertain the role of Lipoprotein (a), C-Reactive protein (CRP) levels and lipids in patients of ischemic stroke.
The study was done in 82 subjects including 40 Computerized Tomography (CT) proven patients of ischemic stroke and 42 age
and sex matched controls. Complete biochemical parameters including lipid profile were carried out on autoanalyzer using standard
kits and reagents. Lipoprotein (a) [Lp(a)] was determined by immunoturbidimetric assay. Atherogenic indices (Total cholesterol/
HDL, LDL/HDL and Lipid Tetrad Index) were calculated using these lipid parameters. The CRP levels were measured semi-quantitatively
by latex agglutination test method. Out of 40 stroke patients, 38 had abnormalities in lipid profile (As per ATP III guidelines).
A significant difference was seen in serum cholesterol, LDL cholesterol and atherogenic indices between the patients and controls.
The difference in CRP levels in cases and control subjects was highly significant (4.78±0.72 mg/dl vs 0.76 ±0.70, p<0.001).
96.5% of patients with raised CRP had abnormal lipid levels also. CRP levels in stroke patients showed significant correlation
with total cholesterol and LDL (p<0.001), Lp (a) (p=0.002) and atherogenic indices (p<0.05). Raised CRP levels in stroke patients
were significantly associated with large territory infarcts, severe disability and poor functional outcome (p<0.05).Genetic
[Lp(a)], metabolic (deranged Lipid profile) and inflammatory factors (CRP) together are instrumental in causing cerebrovascular
arteriosclerosis leading to ischaemic stroke and can be used as important markers to identify patients at risk of severe stroke
and to institute aggressive preventive strategies. 相似文献
558.
Increasing interest in multiple forms of nonacademic intelligences in addition to the well‐established intelligent quotient (IQ) to explain individual success has triggered a need for clear establishment of the theoretical and empirical connection among these constructs. As such, this article explores the interrelationship that exists among three forms of nonacademic intelligences: cultural, emotional, and social. Theoretical and practical implications are also discussed. 相似文献
559.
Amit Kumar Mani Tiwari Abbas Ali Mahdi Sanjay Mishra 《Indian journal of clinical biochemistry : IJCB》2018,33(1):31-37
Iron deficiency anemia is one of the causes that lead to significant mortality and morbidity among pregnant women and fetus. The present study was undertaken to explore oral iron supplementation can modify the metal contents in pregnant anemic women. Iron and folic acid supplementations was given to 500 anemic women (mild = 200, moderate = 200, and severe = 100) and 100 age matched non-anemic controls daily for 100 days. Blood index values and plasma trace minerals were estimated as per standard protocols. Haemoglobin and ferritin levels were found significantly increased (p < 0.001) in anemic and control subjects after treatment. Moreover, the serum transferring receptor levels and total iron binding capacity were found significantly decreased in all treated groups. Iron (Fe), zinc (Zn) and copper (Cu) levels were found increased (p < 0.01) after oral iron supplementation groups. Moreover, selenium (Se) manganese (Mn) and were found to be decreased in all treated groups. Data provides the conclusion that iron and folic acid supplementation recovered the essential trace minerals, except manganese, which may lead to various complications including peroxidation of vital body molecules resulting in increased risk for pregnant women as well as fetus. 相似文献
560.
Manisha Mavai Yogendra Raj Singh R. C. Gupta Sandeep K. Mathur Bharti Bhandari 《Indian journal of clinical biochemistry : IJCB》2018,33(2):222-228
Autonomic activity may be deranged in thyroid dysfunctions and may lead to cardiovascular morbidity and mortality. Myopathy is a common manifestation in thyroid disorders and may be associated with raised serum creatine kinase (CK). We hypothesized that cardiovascular abnormality in thyroid dysfunction may manifest as raised CK-MB. This study was designed to investigate the correlation of CK and its isoform CK-MB with thyroid profile and linear parameters of heart rate variability (HRV). The study was conducted on 35 hypothyroid and hyperthyroid patients each, and 25 age-matched healthy controls. Autonomic activity was assessed by simple short term 5-min HRV. Biochemical evaluation of serum thyroid profile, CK-NAC and CK-MB were estimated in all the subjects. Our results demonstrated low HRV in hypo- as well as hyperthyroid patients. We observed significantly higher serum CK levels in hypothyroid patients when compared to hyperthyroids and controls. However, no significant differences were observed in CK-MB levels in the three groups. Significant positive correlation of CK with TSH and negative correlation with some HRV parameters (LF power, HF power, total power, SDNN, RMSSD) was observed in hypothyroid patients. Whereas correlation of CK-MB with thyroid profile as well as HRV parameters was non-significant in all the groups. Based on the CK and CK-MB findings and their correlation, we conclude that the cardiovascular changes seen in thyroid dysfunctions may primarily be due to autonomic imbalance without apparent cardiac muscle involvement. Whereas, raised CK levels indicate predominantly skeletal muscle involvement in hypothyroid patients. 相似文献