排序方式: 共有69条查询结果,搜索用时 15 毫秒
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Dimple Anand Sabari Das Sumit Ray Seema Bhargava Lalit Mohan Srivastava 《Indian journal of clinical biochemistry : IJCB》2014,29(1):93-96
Sepsis suffers from lack of specific clinical symptoms which contribute to one of the major causes of mortality. In the present study, our aim was to evaluate the role of a recent biomarker Procalcitonin (PCT) in predicting organ dysfunction. 71 patients admitted with sepsis were included in the study. PCT levels were measured at 0, 24, 72 h and 7th day and sequential organ failure assessment score (SOFA) scores were calculated. PCT levels significantly decreased (p < 0.001) in 89.3 % of surviving patients, whereas, in 60 % non surviving patients the PCT level increased significantly (p < 0.001). A significant positive correlation between PCT and SOFA score was observed in survivors at each hour. These observations indicate that PCT concentration is significantly associated with severity of multi organ dysfunction and also helps in determining the prognosis of septic patients. 相似文献
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Bratati Singh Debasis Debadatta Behera Neelam Mehta Seema Das 《Indian journal of clinical biochemistry : IJCB》2014,29(4):517-519
Glycosylated hemoglobin (HbA1c) determination is a powerful means for assessing the evaluation and management of patients with diabetes mellitus. Hemoglobin (Hb) variants and chemically modified derivatives of Hb can affect the accuracy of measurement of HbA1c done by various analytical methods. We report a patient with a rare variant of Hb (Hb Hope) that caused an abnormally high value of HBA1c when assayed using immunoturbidimetric assay (“Tina-quant” 2nd generation assay) and also elucidate the nature of the variant. 相似文献
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Seema Pavaman Sindgikar Deepthi Raran Veetil Rathika D. Shenoy Vijaya Shenoy 《Indian journal of clinical biochemistry : IJCB》2014,29(4):514-516
The presentation of long-chain fatty acid oxidation disorders (FAOD), unlike short and medium-chain disorders can be with secondary defects in mitochondrial function along with typical features of FAOD. We report an infant with Reye-like presentation and acylcarnitine profile suggestive of very-long-chain acyl-CoA dehydrogenase deficiency who had lactic acidosis and urine gas chromatographic pattern of mitochondrial defects. 相似文献
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This study examines the fate of the development model of public broadcasting in the face of rapid global media commercialization. Using the Indian broadcaster Doordarshan as an example, the authors illustrate how a public media outlet with a development mandate has responded to new pressures and examine the consequences for development broadcasting in general. This inquiry challenges not only the strategies of this broadcaster but also some of the assumptions by media scholars regarding development broadcasting. The study concludes by advocating a new type of development broadcasting that establishes a distinct brand and plays a vital role in creating an informed citizenry. 相似文献
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Singh Rishabh Timbadia Devansh Kapoor Vidhi Reddy Rishabh Churi Prathamesh Pimple Omkar 《Education and Information Technologies》2021,26(4):4151-4179
Education and Information Technologies - Mobile learning has been increased in past years and has attracted the interests of academicians and educators in the past many years especially in higher... 相似文献
57.
This two-part article considers certain fundamental symmetries of nature, namely the discrete symmetries of parity (P), charge conjugation (C) and time reversal (T), and their possible violation. Recent experimental results are discussed in some depth. In the first part of this article
we present a general background and discuss parity violation.
B Ananthanarayan is at the Centre for Theoretical Studies, Indian Institute of Science His research interests are in the field
of elementary particle physics.
J Meeraa is finishing her MSc at the Indian Institute of Technology, Chennai.
Bharti Sharma is finishing her MSc at Aligarh Muslim University.
Seema Sharma is finishing her MSc at the University of Rajasthan, Jaipur.
Ritesh K Singh is working towards his PhD at the Indian Institute of Science in the field of elementary particle physics. 相似文献
58.
Dengue fever is one of the major health problems in India. Interaction with specific receptor(s) at the cell surface is one
of the first events in the pathogenesis of Dengue virus. However, relatively little is known about these receptors. Cellular
receptors in human monocytes and mouse neural cells are main target for the viral infection. The envelope protein of the virus
(E-protein) plays important role in attachment of virus to target cells and their interaction with cellular receptors. The
modulation of receptor gene(s) and/or protein(s) can be used as a method for interfering with virus entry and can thus become
a new method for disease prevention. The receptors can be purified by affinity chromatography using E-protein as ligand. It
has been reported that addition of highly sulfated heparan sulfate prevents E-protein binding to target cells suggesting that
heparan sulfate is utilized by dengue envelope protein to bind to target cells. 相似文献
59.
Tester F. Ashavaid Seema P. Todur Alpa J. Dherai 《Indian journal of clinical biochemistry : IJCB》2005,20(2):110-118
The central role of the laboratory scientist is to aid the clinician, in interpreting observed values, by providing relevant
reference values in a convenient and practical form. In India, reference values used in laboratories have been established
in the western population. But these can be questioned due to differences in genetic load, lifestyle, and diet. This review
highlights the approach for establishing reference values in our population using the IFCC guidelines and our observations
from our data as compared to the reported values in our laboratory. 相似文献
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Anjali Manocha L. M. Srivastava Seema Bhargava 《Indian journal of clinical biochemistry : IJCB》2017,32(3):261-265
Lead exposure is increasingly becoming an important risk factor for osteoporosis. In adults, approximately 80–90 % of absorbed lead is stored in the bones. These bone lead deposits are released into the blood during periods of enhanced bone resorption like menopause, forming a potential endogenous source of lead exposure. Postmenopausal women are at a higher risk for bone lead release because of hormonal and age related changes in bone metabolism. Estrogen deficiency is associated with increase in osteoclasts number and activity leading to both the early and late form of osteoporosis. Hence, high blood lead level coupled with concomitant environmental exposure exposes women in this age group to lead related adverse outcomes like hypertension, reduced kidney and neurocognitive functions as well as increased risk of atherosclerosis and cardiovascular mortality. A few studies have also identified coexisting variates like ethnicity, occupation, residence, education, smoking, alcohol medications, water etc. as significant determinants of bone and blood lead in women, thus increasing the magnitude of postmenopausal bone changes. Hence, interventions focused on reducing the intensity of bone resorption during menopause will help decrease exposure to endogenous lead. This would play a significant role in decreasing the morbidity and mortality associated with menopause. Also, identification of modifiable factors that prevent bone lead release will reduce the risk of chronic lead exposure and improve the health outcomes of post-menopausal women. 相似文献