A conceptual model of taste receptors

Of all the senses, that of taste is perhaps the hardest to define and quantify and elucidation of the underlying mechanisms is unrespondingly difficult. This article describes a conceptual model — at the molecular level — for the four basic taste modalities, using apparent specific volume as a fundamental parameter. It also considers possible practical applications.     

桑螵蛸脂类提取物对铜绿假单胞菌的抗菌活性和抗生物膜作用（英文）

目的:探究桑螵蛸脂类提取物的成分及对铜绿假单胞菌的抗菌和抗生物膜作用。创新点:中国传统中药桑螵蛸一直广泛应用于肾病的治疗,在抗菌领域未见报道,本实验首次证明桑螵蛸脂类提取物对铜绿假单胞菌有明显的抗菌和抗生物膜作用。方法:采用气相色谱-质谱联用技术,测定桑螵蛸脂质提取物的化学成分及其相对比例。采用纸片扩散法和琼脂平板稀释法观察桑螵蛸脂类提取物对铜绿假单胞菌的抑菌效应并测定最小抑制浓度(MIC)。采用结晶紫染色法和扫描电镜(SEM)进行抑制生物被膜的试验。结论:桑螵蛸脂类提取物中含有16种化合物,最丰富的成分分别是倍半萜类化合物、单萜和微量芳香族化合物。桑螵蛸脂类提取物对铜绿假单胞菌的MIC为4 mg/ml,对铜绿假单胞菌生物被膜的抑制作用明显。     

Physicochemical characteristics of various milk samples available in Pakistan

We report physicochemical characteristics of various kinds of liquid milk commercially available in Pakistan in comparison with those of fresh natural milk from animals. Milk samples were collected from local markets at Peshawar, Pakistan,and analyzed for their physical features, including moisture, total solids, specific gravity, conductivity, viscosity and titratable acidity (lactic acid equivalent), and chemical components and macro-minerals, including total protein, casein, lactose, ash and minerals (Na, K and Mg). These items were compared with the physicochemical characteristics of the fresh natural milk samples from buffalo, cow and goat. The results were also compared with reported nutritional quality of milk from various countries and World Health Organization (WHO) standards. We found that all the physical features and chemical components of commercially available milk in Pakistan markets meet WHO's requirements, except for Na, K, Ca and Mg, which are below the standards.     

Age-Dependent Changes in Glutathione-S-Transferase: Correlation with Total Plasma Antioxidant Potential and Red Cell Intracellular Glutathione

The correlation between antioxidant capacity and oxidative damage during aging has been reported in several tissues in different species. Glutathione-S-transferases (GST) can metabolise endogenous and exogenous toxins and carcinogens by catalysing the conjugation of diverse electrophiles with reduced glutathione (GSH). We observe a significant (P < 0.001) increase in plasma GST activity as a function of human age (r = 0.5675). A significant (P < 0.001) positive correlation (r = 0.8979) is observed between GST activity and total plasma antioxidant potential measured as ferric reducing ability of the plasma (FRAP). GST activity and red cell intracellular GSH also show a significant positive correlation (r = 0.7014). We hypothesize that the increased activity of plasma GST is a manifestation of increased generation of ROS and a concomitant decrease in the level of plasma antioxidant capacity during aging.     

Higher education in Federally Administered Tribal Areas of Pakistan after 9/11： Problems and prospects

The troubled state of affairs in the Federally Administered Tribal Areas （FATA） of Pakistan portends serious repercussions and grave consequences, destined to affect education particularly higher education in the entire tribal belt. Ironically, no extensive study has been conducted, to investigate those dimensions of FATA higher education which have been adversely affected in the aftermath of 9/11. This exploratory study examines those areas which have been badly affected as a result of current turmoil. In fact, the higher education in FATA has its own peculiar dynamics. Inherently, the entire tribal region has very few well-maintained and properly equipped colleges. Lack of adequate educational facilities, multiplied poor security environment has aggravated the entire situation. Law and order situation in the region has undermined the already dilapidated monitoring mechanism of education department. This state of affairs provides breeding ground for extremist propensities and radical tendencies. In reality, very little attention has been devoted to reform the education system in tribal areas. The whole set up needs to be rehabilitated by taking recourse due to the proactive role of international community. The paper concludes with recommendations for policy makers besides offering new avenues for further research.     

Communications For Developing Nations

Charlotte Dietrich, Der Rundfunk in Afrika An fang der Siebziger Jahre: Strukturen and Daten (Broadcasting in Africa in the Early Seventies: Structures and Data) (Department of Mass Communication, University of Salzburg, Sigmund Haffner Gasse 18, A-5020 Salzburg, Austria---$5.00, paper, plus cost of shipping)

Communication Policy and Planning for Development: A Selected Annotated Bibliography by Syed A. Rahim (285 pp., October 1976, price not given, paper)

An Overview of Communication Research in Asia: Status, Problems and Needs by Gloria D. Feliciano (20 pp., June 1973, on request, paper)

Mass Media Use and the “Revolution of Rising Frustrations:” A Reconsideration of the Theory by Robert C. Hornik (27 pp., July 1974, on request, paper)

Communication and Development in China (Communication Monograph No. 1), by Godwin Chu, et al. (116 pp., September 1976, price not given, paper)

Communication in the Pacific, edited by Daniel Lerner and Jim Richstad (96 pp., June 1976, price not given paper)

The Use of Radio in Adult Literacy Education, by Richard C. Burke (116 pp., £1.50 or about $2.40, paper)

Programmed Instruction for Literacy Workers, by Sivasailam Thiagarajan (136 pp., £1.95 or about $3.12, paper)

Mass Communication in Malaysia, compiled by Lim Huck Tee and V.V. Sarachandran (91 pp., 1975, 12 Singapore dollars outside Asia)

Mass Communication in India, compiled at the Indian Institute of Mass Communication (216 pp., 1976, 18 Singapore dollars outside Asia)     

Pre-service teachers’ and teacher-educators’ experiences and attitudes toward using social networking sites for collaborative learning

Extensive use of social networking sites by students and teachers makes educators and researchers to think whether they can be incorporated in instructional process to facilitate students’ learning. This survey-based study records and examines Pakistani pre-service teachers’ and teacher-educators’ current uses of Facebook, and their attitudes toward using Facebook for collaborative learning, and to see if there is a significant relationship between participants’ intensity of Facebook use and their attitude toward instructional use of Facebook. Results of the study indicated that pre-service teachers’ and teacher-educators’ motives for their current Facebook use are mainly limited for social purposes. Pre-service teachers’ use of Facebook is more intensified than the use of Facebook by teacher-educators. Further, pre-service teachers showed more positive attitudes toward using Facebook for collaborative learning than the attitudes of their faculty. Findings also indicated a positive relationship between participants’ Facebook intensity and their attitudes toward its use for collaborative learning.     

Bridging identities through religious television contents: Javanese female descendants,Islamic viewing and Malay identity projection

This study explores the uses of Islamic television content in bridging the gap between Javanese and Malay identity among the Malay women of Javanese descent in Malaysia. Malaysian religious television programmes have constantly promoted the Islamic identifications of Malayness, enabling the Malay audience to reconstruct the culturally religious identity. While the reconstruction of Islamic identity through television viewing simply represents a lived experience for the majority of the Malay society, it has some cultural meanings for certain Malay sub-ethnic communities, such as the Javanese. This ethnographic study on a Malaysian Javanese community reveals that the interpretive engagement of this particular community in Islamic television viewing serves the purpose of negotiating Malay identity. The results of this study suggest that religious content can serve as an engaging platform to construct multi-ethnic identities beside popular and ethnic-related contents.