人类资源开发组

培训必须适合具体国家与地区的需要。培训的主要目标,是使国家能够:(1)解决诸如保障能源基础、管理环境、保护自然资源;以及(2)迅速提高成年人口的平均科学技术水平,使国家能够采用、开发并有效地应用新技术。经济与社会发展需要科学技术环境。必须从中等教育开始,培养创立与管理这种环境所需的意识与基本技能。国家在经常是大量的证书或文凭持有者身上投入巨额资金,而这些人的技能却不能用或     

安徽读者方辉来信

指出自己在备战英语自考过程中存在的三个主要问题,询问该如何克服: 1.单词记不牢,今天记住了,过两天就忘了。答:小T认为,将单词独立于上下文之外来记忆,是不太可取的方法。尽管很多同学平时都愿意花时间查词典,但通常的做法都是查出中文释义便了事,这种机械的单词记忆方法往往吃力不讨好。因此,小T建议你结合课文背单词。也就是说,在熟读课文的基础上记忆文中出现的所有生词。这样一来,你不仅可以在上下文的帮助下记忆单词的释     

韩国济州岛:潮汐召唤着海女

荷兰水手亨德里克·哈梅尔曾出版他的日志,里面记载了1653年在斯佩威尔号游艇失事后,他和同伴在济州岛上被关押长达13年的经历。即使在当时,神奇的海女就已经吸引并迷住了那些西方人,他们听到她们奇异的叫声,把岛上古怪的女人称为美人鱼。     

八卦掌创始人董海川的武术精研

内家拳法的代表八卦掌始创于董海川之手。此人一生痴迷武学,人生数度沉浮,门下吸引了上千学武之人,将他的八卦掌发扬光大。董海川嫉恶如仇、为人正直,凭借一身武艺行侠仗义,书写了一段段武林传奇。     

浅谈我国高等教育改革的发展

高等教育是教育事业的龙头,高等教育的发展对于我国社会主义建设意义重大,而我国高等教育的发展还存在很多问题,因而必须推进以提高质量的高等教育改革。本文主要分析了我国高等教育发展中存在的问题,进而提出了高等教育的发展方向。     

Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells

Due to their toxicity, the increased distribution of microcystins (MCs) has become an important worldwide problem. MCs have been recognized as inhibitors of protein phosphatase 2A (PP2A) through their binding to the PP2A catalytic subunit. However, the exact mechanism of MC toxicity has not been elucidated, especially concerning the cellular response and its autoregulation. To further dissect the role of PP2A in MC-induced toxicity, the present study was undertaken to determine the response of PP2A in human amniotic epithelial (FL) cells treated with microcystin-LR (MCLR), one of the MC congeners. The results show that a low-dose treatment of MCLR in FL cells for 6 h induced an increase in PP2A activity, and a high-dose treatment of MCLR for 24 h decreased the activity of PP2A, as expected. The increased mRNA and protein levels of the PP2A C subunit may explain the increased activity of PP2A. Furthermore, MCLR altered microtubule post-translational modifications through PP2A. These results further clarify the underlying mechanism how MCLR affects PP2A and may be helpful for elucidating the complex toxicity of MCLR.