Age-Related Changes of Serum Soluble Interleukin 9 Receptor (sIL-9Rα) in Healthy Subjects

Most cytokine receptors including interleukin (IL)-9 have soluble counterparts in body fluids. We planned to investigate the pathophysiological significance of the serum soluble IL-9 receptor (sIL-9R) level. We determined the serum sIL-9Rα chain (sIL-9Rα) levels in 96 healthy Japanese individuals to establish a control value by means of specific human sIL-9Rα ELISA, followed by a preliminary application in a patient with diarrhea positive hemolytic uremic syndrome. Age was negatively correlated with the sIL-9Rα level (Spearman r = −0.241, n = 96, p = 0.0180). The serum sIL-9Rα level showed a progressive decline to the normal adult level by the age of 30. The serum sIL-9Rα level of the patient with HUS was markedly higher than those of the age-matched control from the onset of the disease. Because of the remarkable age-dependent variability of sIL-9Rα in healthy subjects, disease-related changes, as well as therapy-dependent alterations, should be considered with caution. Thus, it is recommended that when the serum sIL-9Rα levels of patients are evaluated, the values should be compared with those of age-matched controls. The established control value will be used to discriminate between normal and the pathological conditions in our future studies.     

Circles on pommel horse with a suspended aid: spatio-temporal characteristics

A suspended aid is popular for learning circles and for refining circle technique on pommel horse. The aim of this study was to investigate the effect of using a suspended aid on the biomechanical characteristics of circles. This first study focused specifically on the spatio-temporal characteristics of circles. Eighteen gymnasts performed three sets of 10 circles with and without a suspended aid on a pommel horse under which two force plates were set. Three-dimensional coordinates were acquired using 13 Qualisys motion tracking cameras operating at 100 Hz. The results showed that circles with the aid were characterised by a smaller body flexion angle, a greater shoulder angle, a greater ankle circle diameter, earlier hand releases, and a longer total duration. In contrast, the body lateral flexion angle, the arm-leaning angle, and the shoulder circle diameter remained relatively similar to circles without the aid. It was confirmed that circles with the aid actually appeared to be more desirable in terms of the movement amplitude. In this sense, a suspended aid could function as spotting, which is often used for a progression to learn gymnastics skills and to let gymnasts experience a desired movement pattern.     

Validity of block start performance without arm forces or by kinematics-only methods

The purpose of this study was to validate the calculation of reaction time (RT) and normalised power in block starts without considering arm ground reaction forces (GRFs) or using two kinematics-only methods. The RT and normalised power in the action phase were calculated using four different methods: using GRFs of arms and legs by force plates (whole F-based method), which can be regarded as the most valid method, using GRFs of legs captured by force plates (legs F-based method), using position of the centre of mass of the entire body captured by high-speed cameras (whole P-based method), and using only a partial subset of segment position (partial P-based method). Bland–Altman plots demonstrated that the RT of the legs F-based method was not similar to that of the whole F-based method: the mean difference was 7.4 ms and the 95% limits of agreement was?45.1 to 59.8 ms, and it was the least valid method for the calculation among the four methods. In contrast, the normalised power was more valid in the legs F-based method, followed by whole and partial P-based methods. This information will help researchers and practitioners to decide upon their analysis methods when analysing block start performance.