Savouring Rajasthan's Shiksha Karmi in a remote village: the prospect of dismantling the student-teacher divide

The Shiksha Karmi Project in Rajasthan, one of the most educationally challenged states, is at the frontiers of alternative models of primary education in India. The key ideas underlying this model are: (i) the taking over of ‘sick’ schools in remote regions of the state and turning them around, (ii) creating new schools driven by demand from the ground, (iii) human resource investments to train local village teachers, (iv) strong linkages between the school and the community built upon a spirit of voluntarism, (v) an explicit movement toward gender equity and (vi) a bold attempt at the universalization of primary education through a combination of formal and non-formal institutions. This article provides a grounded feel for the Shiksha Karmi Project in a stellar school, Meena Dant Ka Pura. While the case highlights the shortage of locally based female teachers in the entire Shiksha Karmi Project, it also suggests the very real possibility of employing Shiksha Karmi Project alumni and higher grade students in teaching roles. Overall, primary education in India has much to learn from the Shiksha Karmi Project experience.     

Use of specific IgE to fractions of gynandropsis gynandra pollen inin vitro diagnostic test

The study was aimed at presence of specific IgE antibody levelsinvitro to the identified antigen. Based on positive skin test with Gynandropsis gynandra and elevated levels of total IgE (>325 IU/ml) 104 patients were selected. Healthy, asymptomatic individuals (25) with low total IgE (<325 IU/ml) were included as controls. The mean OD values by ELISA for specific IgE were 0.67±0.21, 0.57±0.18 and 0.56±0.18 with whole pollen antigen, 46-37 kD fraction and 36-32 kD fraction, respectively. The specificity and sensitivity between skin test positivity with whole pollen antigen verses fraction with mol.wt 46-37 kD was 90% and 90% and for fraction with mol.wt 36-32 kD was found to be 81.1% and 89.4%. The clusters with molecular weights 46-37 kD and 36-32 kD may be useful inin vitro diagnostic test. Fractions within these clusters need to be identified for a higher specificity.     

Assessment practices of educational psychologists in Aotearoa/New Zealand: from diagnostic to dialogic ways of working

Psychologists working in education in Aotearoa/New Zealand work in diverse educational environments making day-to-day decisions informed by evidence-based practice. As a relatively small professional group with a complex work programme, they contribute to the assessments and decision-making processes of children and young people across multiple settings. This paper explores the results of a small-scale national survey of psychologists working in education through the Ministry of Education. Results showed that these psychologists use at least 25 assessment methods including assessments within behavioural, emotional, social, and cognitive domains. The assessment data are used for three primary reasons: to understand the child, inform decision-making, and contribute to discussions around appropriate interventions. The use of interviews, observation and collaboration were identified as key to their assessment practices, illustrating a preference towards more dialogic and ecological ways of working. While the majority used assessment practices that align with facilitating the learning of the child across contexts, the psychologists reported that ethical dilemmas arose when they were expected to be more diagnostic in their focus.     

Alteration of Micronutrient Status in Compensated and Decompensated Liver Cirrhosis

Decompensation followed by death is the most serious outcome in patients suffering from cirrhosis of the liver. Alteration of trace elements may play a vital role in the process of decompensation. To examine the change in status of trace elements during the decompensation process, we analysed the zinc, copper, iron, magnesium, bilirubin and albumin levels in the serum of compensated (n = 34) and decompensated (n = 31) liver cirrhosis patients and compared them with healthy control group (n = 36) by post hoc ANOVA. We observed significant alteration in the selected micronutrients in the diseased group relative to healthy controls (P < 0.05). Moreover, mean serum zinc and iron levels were significantly lower with a higher level of serum copper in decompensated cirrhosis group than in compensated group (P < 0.05). However, no significant decrease of serum magnesium was found between the two diseased groups. Our findings imply that the trace elements like zinc, copper and iron might exert important contributory roles in decompensation process in liver cirrhosis and hence, may be utilized as important biomarkers for these patients. Furthermore, we propose that replacements of those micronutrients at an early stage can delay or prevent the severe outcomes like hepatic encephalopathy, gastrointestinal bleeding, severe jaundice or ascites in these patients.     

Fatty Acid Oxidation Disorder with Secondary Mitochondrial Energy Production Defect: A Case Report

The presentation of long-chain fatty acid oxidation disorders (FAOD), unlike short and medium-chain disorders can be with secondary defects in mitochondrial function along with typical features of FAOD. We report an infant with Reye-like presentation and acylcarnitine profile suggestive of very-long-chain acyl-CoA dehydrogenase deficiency who had lactic acidosis and urine gas chromatographic pattern of mitochondrial defects.     

Interferences in clinical chemistry analysis

Analyses of body fluids in clinical chemistry laboratory are subject to a number of interferences that affect the analytical accuracy. The interferents arise from exogenous sources like drugs and additives as well as such endogenous sources like lipemia, hemolysis and icteria. Our studies demonstrate matrix interference in the form of analytical blas between serum and aqueous matrix calibrators. The clinical chemist should constantly be aware of this factor. Correction of interferences is recommended as an integral part of the quality assurance program.