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Krilowicz B Johnston W Sharp SB Warter-Perez N Momand J 《CBE life sciences education》2007,6(1):74-83
A summer program was created for undergraduates and graduate students that teaches bioinformatics concepts, offers skills in professional development, and provides research opportunities in academic and industrial institutions. We estimate that 34 of 38 graduates (89%) are in a career trajectory that will use bioinformatics. Evidence from open-ended research mentor and student survey responses, student exit interview responses, and research mentor exit interview/survey responses identified skills and knowledge from the fields of computer science, biology, and mathematics that are critical for students considering bioinformatics research. Programming knowledge and general computer skills were essential to success on bioinformatics research projects. General mathematics skills obtained through current undergraduate natural sciences programs were adequate for the research projects, although knowledge of probability and statistics should be strengthened. Biology knowledge obtained through the didactic phase of the program and prior undergraduate education was adequate, but advanced or specific knowledge could help students progress on research projects. The curriculum and assessment instruments developed for this program are available for adoption by other bioinformatics programs at http://www.calstatela.edu/SoCalBSI. 相似文献
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Grisham W Schottler NA McCauley LM Pham AP Ruiz ML Fong MC Cui X 《CBE life sciences education》2011,10(2):222-230
Zebra finch song behavior is sexually dimorphic: males sing and females do not. The neural system underlying this behavior is sexually dimorphic, and this sex difference is easy to quantify. During development, the zebra finch song system can be altered by steroid hormones, specifically estradiol, which actually masculinizes it. Because of the ease of quantification and experimental manipulation, the zebra finch song system has great potential for use in undergraduate labs. Unfortunately, the underlying costs prohibit use of this system in undergraduate labs. Further, the time required to perform a developmental study renders such undertakings unrealistic within a single academic term. We have overcome these barriers by creating digital tools, including an image library of song nuclei from zebra finch brains. Students using this library replicate and extend a published experiment examining the dose of estradiol required to masculinize the female zebra finch brain. We have used this library for several terms, and students not only obtain significant experimental results but also make gains in understanding content, experimental controls, and inferential statistics (analysis of variance and post hoc tests). We have provided free access to these digital tools at the following website: http://mdcune.psych.ucla.edu/modules/birdsong. 相似文献
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DNA曾被认为是遗传信息的惟一贮藏库，但生物学家正在着手破译一个独立的、更有拓展性的，在染色体内被偏码的信息层，遗传学已让路于基因表型学。 相似文献
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刚过去的八月,攻击Internet的蠕虫病毒纷纷发作,其中一种的生存伎俩不同寻常。大无极（Sobig．F)蠕虫病毒通过恶意邮件阻塞网络,冲击渡(Blaster)蠕虫病毒强迫寄主计算机每隔几分钟就要重启,但冲击波杀手 相似文献
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本文通过私募通数据库搜集数据构造匹配样本,使用logit模型、Cox模型和多元线性回归模型,从后续募资的可能性、时间间隔、募资规模三个方面,实证分析引导基金单独参股和联合参股这两种参股方式对创投机构后续募资的影响。研究发现:(1)引导基金联合参股可以促进创投机构后续募资,而单独参股则不能。(2)引导基金无论联合参股高声誉创投机构还是低声誉创投机构,都会促进其后续募资。(3)引导基金联合参股非国有背景创投机构可以促进其后续募资,但联合参股国有背景创投机构则不能促进其后续募资。 相似文献
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