Learning & Behavior - Eye movements of four stumptailed monkeys were measured during performance of simple and ambiguous form discriminations. Duration of fixations increased during learning of... 相似文献
Psoriasis is a chronic inflammatory, proliferative skin disease characterized by pathological skin lesions due to various exogenous and endogenous factors. It is associated with a number of biochemical and immunological disturbances. Recently, it has been suggested that increased reactive oxygen species (ROS) production and compromised function of antioxidant system may be involved in the pathogenesis of this disease. In the present study, 90 psoriasis patients were selected. Disease severity was assessed by psoriasis area severity index score and grouped as mild, moderate and severe (each group consists of 30 subjects) and compared with 30 healthy controls. Serum levels of malondialdehyde, nitric oxide end products and the activities of antioxidant enzymes such as erythrocyte-superoxide dismutase, catalase and total antioxidant status were investigated in these groups/subjects. As compared to controls, we found severitywise significantly increased serum malondialdehyde, nitric oxide end products with decrease in erythrocyte-superoxide dismutase activity, catalase activity and total antioxidant status in patients with psoriasis suggesting worsening of the disease. It seems to be linked with the enhancement of Reactive Oxygen Species production and decreased antioxidant potential in psoriasis. 相似文献
Hemodialysis represents a chronic stress status for its recipients. Many hypotheses state that this may be associated with
oxidative stress. Thus, there may be deficiency of antioxidants like erythrocytic superoxide dismutase, catalase, vitamin
E or increased generation of free radicals like superoxide anions. A study was carried out to investigate oxidant and antioxidant
status in chronic renal failure patients undergoing hemodialysis and effect of vitamin E supplementation on these two status.
Blood samples were collected from patients before and after hemodialysis and from controls. The samples were analyzed for
quantitation of MDA as index of lipid peroxide, nitric oxide, vitamin E, vitamin C and enzymatic antioxidants namely erythrocyte
SOD and catalase. As compared to controls, the levels of serum MDA were significantly increased and activities of erythrocyte
SOD and catalase, levels of serum nitric oxide, serum vitamin E and plasma vitamin C were significantly decreased both before
and after hemodialysis. The efficiency of vitamin E therapy in hemodialysis patients was assessed by re-evaluating oxidant
and antioxidant status of same patients after supplementation of vitamin E. Vitamin E supplementation caused decrease in serum
MDA and increase in levels of serum nitric oxide, vitamin E, vitamin C and activities of erythrocytic SOD and catalase. Our
results suggest the presence of oxidative stress and the possible preventive role of vitamin E therapy in hemodialysis patients. 相似文献
The performance of parallel query processing in a cluster of index servers is crucial for modern web search systems. In such a scenario, the response time basically depends on the execution time of the slowest server to generate a partial ranked answer. Previous approaches investigate performance issues in this context using simulation, analytical modeling, experimentation, or a combination of them. Nevertheless, these approaches simply assume balanced execution times among homogeneous servers (by uniformly distributing the document collection among them, for instance)—a scenario that we did not observe in our experimentation. On the contrary, we found that even with a balanced distribution of the document collection among index servers, correlations between the frequency of a term in the query log and the size of its corresponding inverted list lead to imbalances in query execution times at these same servers, because these correlations affect disk caching behavior. Further, the relative sizes of the main memory at each server (with regard to disk space usage) and the number of servers participating in the parallel query processing also affect imbalance of local query execution times. These are relevant findings that have not been reported before and that, we understand, are of interest to the research community. 相似文献
Methods for identifying students with learning disabilities continue to be an area of controversy. The present investigation examined the impact of implementing statewide guidelines for the identification of these students. Data were collected from multidisciplinary team reports on 718 students with learning disabilities who were referred and labeled during the 1983-84 school year (before implementation of statewide learning disability guidelines) and 790 students who were identified during 1987-88 (after implementation of the guidelines). The results of the study revealed that the statewide guidelines significantly changed the characteristics of students who were identified. After the implementation of the guidelines, students with much more severe academic problems were identified. These students were much more likely to have a severe discrepancy and be chronically failing in the regular classroom. However, even with explicit, widely accepted guidelines, approximately one third of all students identified in 1987-88 failed to meet the stated criteria for identification. The implications of these findings for professional practice and future research are discussed. 相似文献
Internships are an effective way of connecting high school students in a meaningful manner to the sciences. Disadvantaged minorities have fewer opportunities to participate in internships, and are underrepresented in both science, technology, engineering, and mathematics majors and careers. We have developed a Summer Academic Research Experience (SARE) program that provides an enriching academic internship to underrepresented youth. Our program has shown that to have a successful internship for these disadvantaged youth, several issues need to be addressed in addition to scientific mentoring. We have found that it is necessary to remediate and/or fortify basic academic skills for students to be successful. In addition, students need to be actively coached in the development of professional skills, habits, and attitudes necessary for success in the workplace. With all these factors in place, these youths can become better students, compete on a more level playing field in their internships, and increase their potential of participating actively in the sciences in the future. 相似文献
Three wishes and primary wishes of fourth- through seventh-grade gifted students participating in a residential program for the gifted were collected and categorized. The results indicated that males wished for material things more often than did females. With the exception of fourth graders, subjects made altruistic wishes more frequently than any other wish. 相似文献
This study had two aims. The first was to test the postulate of analogical equivalents in number processing using a stimulus set based on the differences between pairs of numbers, and second, to look for IQ-dependent differences in this processing. Participants were asked to make judgments concerning the differences between pairs of numbers—each number pair being defined according to overall numerical size and level of difference—and to draw the magnitude of the differences using a free-hand line. In agreement with previous findings, results indicated that the magnitude of participants' responses was dependent on the sizes and levels of the differences within the number pairs. In particular, participants' responses to a difference of nine units at the highest level were based on unit lengths smaller in magnitude compared with other number pairs. In contrast, participants' responses to a second test requiring them to estimate the length of a line using an independent number scale showed remarkable accuracy across all lengths. The results of the two tests did not, however, indicate any difference in responses based on IQ. The results gave support to the idea that transformation of numerical quantities to their analogical equivalents occurs during simple arithmetic sums, and that this transformation was flawed as suggested by the number size effect. 相似文献
The aimof this article is to define and operationalize the construct of infantilism.
The methodsof theoretical research involve analysis and synthesis. Age and content criteria are analyzed for childhood and adulthood. Infantile traits in an adult are described.
Results. The characteristics of adult infantilism in the modern world are defined, taking into account increasing information flows and socio-economic changes. The concept of “infantilism” and its main features are defined as an organization of the personality that includes traits and behavioral models that are typical of one's earlier age periods and not appropriate to the person's actual age, which is most articulately manifested in emotional and volitional immaturity of an individual.
Scientific novelty. The main psychological characteristics of adulthood are described, including reflection, the desire to work and have a vocation, vocational self-determination, work skills, the desire for self-realization, and emotional and volitional maturity. Objective characteristics of adulthood are: transition to economic and territorial independence of the parental family, and development of new social roles, such as that of worker, spouse, and parent. Two possible operationalizations of the concept are identified: objective (existence/absence in a person’s life of objective criteria of adulthood) and subjective (self-report on the subjective feeling of existence/absence of the psychological characteristics of adulthood).
The practical significanceof the work consists in formulation of an operationalization of “infantilism,” which at the moment has so many interpretations. Such operationalization is necessary for further analysis and research.相似文献