档案馆安全保障现状调查与评估——以武汉市35个不同类型档案馆为例

论文对武汉市各类档案馆的安全保障工作进行了调研与评估,从安全战略、基础设施、组织管理、档案安全技术、档案安全制度五个维度分析了档案馆安全保障工作的现状,提出了如下建议:完善应用系统与数据库安全功能、加强安全技术手段应用、加强档案信息风险评估与制度建设.     

Rollback,scissor-like closure of the Mongol-Okhotsk Ocean and formation of an orocline:magmatic migration based on a large archive of age dataOA

Tracing the closure of oceans with irregular margins and the formation of an orocline are crucial for understanding plate reconstruction and continental assembly.The eastern Central Asian Orogenic Belt,where the Mongol-Okhotsk orocline is situated,is one of the world’s largest magmatic provinces.Using a large data set of U-Pb zircon ages,we updated the timing of many published igneous rocks,which allowed us to recognize tightly ’folded’ linear Carboniferous-Jurassic magmatic belts that wrap arou...     

个性化图书推荐研究

个性化图书推荐系统通过对用户借阅行为的统计分析,获取用户的兴趣特征,实现由原来的人找书到书找人一对一的个性化图书推荐。现有的图书推荐系统各有侧重,图书推荐算法及评价标准各具优、缺点。未来,图书推荐的研究热点及难点将集中在借阅记录的稀疏性、新图书问题、高校新生问题、用户统计学信息、根据《中国图书馆分类法》计算图书相似性、副本数及借阅规章制度等方面。     

电子图书对图书馆的影响及对策

电子图书在馆藏和阅读、读者及馆员素质要求、馆舍及设施、读者服务及图书馆评价等方面都对图书馆有重要影响。图书馆人应当正确认识电子图书的影响和作用 ,积极开展电子图书的研究 ,逐步建立电子图书的传播环境 ,开展电子图书利用的馆员及读者培训工作 ,做好其收藏和使用工作。参考文献 6。     

基于数字参考咨询适度服务的资源开放获取研究

文章首先提出数字参考咨询适度服务、资源开放获取的概念以及开放获取的条件基础、过程和方式,然后分析数字参考咨询适度服务对开放获取的影响,划分出适度服务区间,以解决资源开放获取的障碍.     

Two decades of suspect evidence for adaptive molecular evolution—negative selection confounding positive-selection signals

There has been a large literature in the last two decades affirming adaptive DNA sequence evolution between species. The main lines of evidence are from (i) the McDonald-Kreitman (MK) test, which compares divergence and polymorphism data, and (ii) the phylogenetic analysis by maximum likelihood (PAML) test, which analyzes multispecies divergence data. Here, we apply these two tests concurrently to genomic data of Drosophila and Arabidopsis. To our surprise, the >100 genes identified by the two tests do not overlap beyond random expectation. Because the non-concordance could be due to low powers leading to high false negatives, we merge every 20–30 genes into a ‘supergene’. At the supergene level, the power of detection is large but the calls still do not overlap. We rule out methodological reasons for the non-concordance. In particular, extensive simulations fail to find scenarios whereby positive selection can only be detected by either MK or PAML, but not both. Since molecular evolution is governed by positive and negative selection concurrently, a fundamental assumption for estimating one of these (say, positive selection) is that the other is constant. However, in a broad survey of primates, birds, Drosophila and Arabidopsis, we found that negative selection rarely stays constant for long in evolution. As a consequence, the variation in negative selection is often misconstrued as a signal of positive selection. In conclusion, MK, PAML and any method that examines genomic sequence evolution has to explicitly address the variation in negative selection before estimating positive selection. In a companion study, we propose a possible path forward in two stages—first, by mapping out the changes in negative selection and then using this map to estimate positive selection. For now, the large literature on positive selection between species has to await reassessment.     

论合并高校医学人文课程设置基本原则

独立医学院校与综合性大学或多科性大学合并的目的之一在于加强医学人文教育,合并高校在利用人文社会科学优势促进医学人文课程的优化设置的过程中要坚持综合性原则、关联性原则、协调性原则、整体性原则、重点性原则、实效性原则、适度性原则、专业性原则、探索性原则。     

高等学校学生工作项目化管理的经济学思考

经济学中项目管理的内涵包括确定项目和实施项目两项内容,项目管理有优化项目资源配置和协调项目矛盾与冲突两大功能。将项目管理的基本理念运用到高等学校学生管理工作．可以最大限度地利用现有的学生活动资源、规范管理行为、降低管理成本、提高工作效率,实现培养大学生综合素质和创新能力的目的。     

任务驱动教学法下的能源与动力工程基础实验实训探索和改革

分析能源与动力工程基础实验实训现状和存在问题,将任务驱动教学法应用于基础实验实训,突出学生为主、融入新兴理念、培养创新意识、细化实训要求、完善考核机制和扎实能力培养.通过基础实验的自学和检测,锻炼学生操作实验、撰写报告和分析结果的能力.设计实验的任务驱动,给学生充分发展的平台,锻炼其自学、实践、表达和团队协作能力,培养...     

流氓软件原理及解决方案

介绍流氓软件的相关概念、分类及危害。通过分析流氓软件的作用原理,探讨对此类软件的解决方案和防范措施,给电脑用户提供参考技术。