Integration Factors Related to the Academic Success and Intent to Persist of College Students with Learning Disabilities

Despite increased enrollment, outcomes such as grade point average (GPA), persistence, and graduation rates for college students with learning disabilities (LD) continue to lag behind those of their nondisabled peers. Reasons for the differences vary but may include academic and social integration, factors identified as important to the success of college students in general. This research investigated the relative influence of background characteristics, precollege achievement, and college integration variables on the academic success and intent to persist of college freshmen and sophomores with LD. While academic and social integration were not unique predictors of college GPA, both integration variables were unique predictors of intent to persist. The findings suggest that beyond high school achievement and background characteristics, college experiences as captured by academic and social integration are promising constructs to help explain the persistence of college students with LD. Implications for future research and practices for high school and college personnel are discussed.     

高校档案工作管理模式浅谈

改革旧的高校档案分级管理模式，建立跨世纪的集中统一管理模式。为高校的发展和社会的需求提供高效、快捷及多方位的信息服务，是实现为经济建设服务的关键。     

浅谈校园网与档案馆网络化建设的构想

校园网的建设，给高校档案馆网络化建设带来了难得的机遇．但网络缺乏统一的协调机构。标准化水平较低。馆员整体素质低，无法满足用户的多种需求，给档案网络化建设和资源共享造成隐患。通过对这些问题的分析，提出高校档案网络化建设的构想．     

骨骼肌基因转移系统的建立

以EGFP为标记基因，利用重新构建的pAV-EGFP质粒，采用直接注射方法，进行了离体和在体基因转移研究。实验结果显示，经脂质体包裹后，质粒可以有效地进行细胞转移；DNA表达载体肌肉直接注射后，利用共聚焦显微镜可以在注射点周围的肌细胞观察到绿色荧光蛋白；而在对侧肢PCR和共聚焦显微镜的结果均为阴性。实验结果表明，肌肉直接注射DNA可以在肌肉得到表达，将会为治疗肌肉损伤带来新的方法。     

基于改进编码的多聚脯氨酸二型结构预测

目前使用机器学习方法对稀有的PPII二级结构进行预测工作还比较少见.本文在分析数据集的特征基础之上,采用加强局部信息的改进编码方法,并使用生物信息学中常用的BP神经网络来预测PPII二级结构.通过对不同输入窗口长度与不同隐层节点数的神经网络进行训练和测试,得出在输入窗口长度为5个氨基酸残基和隐结点数为8时PPII螺旋结构能够被很好地预测出来,此时的预测敏感度为82.5%.     

Investigation of Poor Academic Achievement in Children with Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD) is a neurogenetic developmental disorder that presents with progressive muscular weakness. It is caused by a mutation in a gene that results in the absence of specific products that normally localize to muscle cells and the central nervous system (CNS). The majority of affected individuals have IQs within the normal range, generally with lower verbal than performance IQ scores. Prior work has demonstrated selective deficits on tests of verbal span and immediate memory. For the current study, 26 boys with DMD (and normal intellectual function) and their unaffected siblings were evaluated. Paired comparisons demonstrated that the children with DMD had significantly poorer academic achievement scores than their siblings, even though their vocabulary levels and home and educational environments were comparable. Children with DMD also had more behavioral concerns, physical disabilities, and poorer verbal memory spans. Linear regression indicated that behavioral concerns, executive function, and physical disability did not contribute substantially to academic performance, whereas performance on verbal span did. DMD presents with a selective developmental aberration in verbal span that has wide‐ranging consequences on learning skills.