微生物教学实验室生物安全的探索与研究

安全稳定是当今高校快速发展的根本保障,是建设和谐校园、平安校园的切入点和着力点。北京工业大学生命科学与生物工程学院微生物教学实验室,是伴随招收生物技术研究方向的本科生而诞生的专业基础教学实验室。由于教学和科研的密切关系,在病毒与药理研究室生物安全实践的基础上,从微生物教学实验室的特点等4个方面,对微生物教学实验室的生物安全问题进行有益的探索与研究,不仅提升师生的安全意识,同时有效促进实验教学的改革和创新。     

网络课程的内容进化机制设计与技术实现

当前我国网络课程建设与应用普遍存在以下问题:课程内容结构封闭和更新迟缓,教学形式具有单向传递性;课程内容与学习活动在应用上的分离,影响学生主体地位的发挥;不同教学学期衔接或课程内容在不同教师间共享时,教学过程中的生成性资源存在丢失的现象。因此,探讨如何根据网络课程内容进化理念,提供相应的环境与机制,从而促进学习内容、教师及学生三者在网络教学过程中的交互,并通过积聚大众智慧来促进课程内容的动态发展,对于提高网络课程教学质量具有重要意义。     

混合式教学模式下学生自主学习能力发展策略研究

随着教育改革的不断深入,教育理念和教学方式发生了很大的变化,变化来自国家的重视和教育实施主体的积极参与。在教育过程中开展线上线下混合式教学是对传统教学方式的突破和创新,教学过程注重学生能力培养,混合式教学模式对于激发学生学习兴趣、提升学生自主学习、培养学生学习能力有着重要的现实意义。     

Enabling Mg metal anodes rechargeable in conventional electrolytes by fast ionic transport interphase

Rechargeable magnesium batteries have received extensive attention as the Mg anodes possess twice the volumetric capacity of their lithium counterparts and are dendrite-free. However, Mg anodes suffer from surface passivation film in most glyme-based conventional electrolytes, leading to irreversible plating/stripping behavior of Mg. Here we report a facile and safe method to obtain a modified Mg metal anode with a Sn-based artificial layer via ion-exchange and alloying reactions. In the artificial coating layer, Mg₂Sn alloy composites offer a channel for fast ion transport and insulating MgCl₂/SnCl₂ bestows the necessary potential gradient to prevent deposition on the surface. Significant improved ion conductivity of the solid electrolyte interfaces and decreased overpotential of Mg symmetric cells in Mg(TFSI)₂/DME electrolyte are obtained. The coated Mg anodes can sustain a stable plating/stripping process over 4000 cycles at a high current density of 6 mA cm⁻². This finding provides an avenue to facilitate fast ion diffusion kinetics of Mg metal anodes in conventional electrolytes.     

图书馆在倡导信息公平、构建和谐社会中的地位

公平是和谐社会的基础.社会公平,是指不同阶层、不同群体之间,都能够公平地获得各种权利和机会,包括公平地享有社会文化资源、文明成果和信息.论述了和谐社会中信息公平的含义,分析了导致信息不公平的原因,提出图书馆应通过一系列举措建立信息公平,促进和谐社会发展.     

天下第一雄关嘉峪关

看到嘉峪关的第一眼,我就觉得此行不虚了。连日来行进在茫茫的戈壁滩上,黄沙浩浩,树与水变成稀罕物,由此我以为嘉峪关也是一片漠漠的黄色,没想到嘉峪关居然是这样的水秀树明,仿佛回到了江南!嘉峪山谷不仅美好,而且地势险要。它南有终年积雪的祁连山,北是     

关于二重积分计算法的补充

在二重积分一般计算方法的基础上,补充了7种计算二重积分的方法,对每种方法给出相应的求解思路,并辅以典型例题,旨在使学生对二重积分的计算方法有更深的理解和掌握.     

社会支持对运动员投入的影响：心理坚韧性与应对方式的序列中介作用

摘要：目的：考察社会支持对运动员投入的影响以及心理坚韧性和应对方式在其中的序列中介作用。方法：采用运动领域领悟支持问卷、运动心理坚韧性问卷、竞技运动领域应对问卷、运动员投入问卷对483名现役运动员进行调查。结果：1）社会支持对运动员投入有显著的正向预测作用;2）心理坚韧性与应对方式在社会支持与运动员投入之间起中介作用。结论：社会支持不仅能直接促进运动员投入,还可以通过心理坚韧性与应对方式的中介对其产生间接促进作用,具体包括4条中介路径：通过心理坚韧性的中介路径;通过任务导向应对的中介路径;通过心理坚韧性与任务导向应对的序列中介路径;通过心理坚韧性与脱离导向应对的序列中介路径。本研究构建的中介效应模型在一定程度上揭示了社会支持影响运动员投入的内在机制。研究提示,通过提供社会支持,将能增强运动员的心理坚韧性,促使其更多地采用任务导向应对,更少地采用脱离导向应对,进而促进运动员投入。     

Injectable hybrid inorganic nanoscaffold as rapid stem cell assembly template for cartilage repair

Cartilage injuries are often devastating and most cannot be cured because of the intrinsically low regenerative capacity of cartilage tissues. Although stem-cell therapy has shown enormous potential for cartilage repair, the therapeutic outcome has been restricted by low survival rates and poor chondrocyte differentiation in vivo. Here, we report an injectable hybrid inorganic (IHI) nanoscaffold that facilitates fast assembly, enhances survival and regulates chondrogenic differentiation of stem cells. IHI nanoscaffolds that strongly bind to extracellular matrix (ECM) proteins assemble stem cells through synergistic 3D cell–cell and cell–matrix interactions, creating a favorable physical microenvironment for stem-cell survival and differentiation in vitro and in vivo. Additionally, chondrogenic factors can be loaded into nanoscaffolds with a high capacity, which allows deep, homogenous drug delivery into assembled 3D stem-cell-derived tissues for effective control over the soluble microenvironment of stem cells. The developed IHI nanoscaffolds that assemble with stem cells are injectable. They also scavenge reactive oxygen species and timely biodegrade for proper integration into injured cartilage tissues. Implantation of stem-cell-assembled IHI nanoscaffolds into injured cartilage results in accelerated tissue regeneration and functional recovery. By establishing our IHI nanoscaffold-templated 3D stem-cell assembly method, we provide a promising approach to better overcoming the inhibitory microenvironment associated with cartilage injuries and to advance current stem-cell-based tissue engineering.     

一次性塑料快餐盒盖成型工艺分析及逆向设计

采用逆向思维方法,详细分析了一次性快餐盒盖的成型工艺,并对其结构进行改进设计。为那些以实物为制造基础的产品的设计提供了借鉴,在缩短产品开发周期,提高经济效益方面,起着重要作用。