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Techniques used to prepare clinical samples have been perfected for use in diagnostic testing in a variety of clinical situations, e.g., to extract, concentrate, and purify respiratory virus particles. These techniques offer a high level of purity and concentration of target samples but require significant equipment and highly trained personnel to conduct, which is difficult to achieve in resource-limited environments where rapid testing and diagnostics are crucial for proper handling of respiratory viruses. Microfluidics has popularly been utilized toward rapid virus detection in resource-limited environments, where most devices focused on detection rather than sample preparation. Initial microfluidic prototypes have been hindered by their reliance on several off-chip preprocessing steps and external laboratory equipment. Recently, sample preparation methods have also been incorporated into microfluidics to conduct the virus detection in an all-in-one, automated manner. Extraction, concentration, and purification of viruses have been demonstrated in smaller volumes of samples and reagents, with no need for specialized training or complex machinery. Recent devices show the ability to function independently and efficiently to provide rapid, automated sample preparation as well as the detection of viral samples with high efficiency. In this review, methods of microfluidic sample preparation for the isolation and purification of viral samples are discussed, limitations of current systems are summarized, and potential advances are identified. 相似文献
83.
This paper examines the links between language, social difference and political domination in the practices of parental school choice at the heart of a global city, Vancouver. Vancouver is a highly diverse city, especially in terms of language. Its inner city is replete with multiple languages whose exchange values are not equal. In this context, our case study of two elementary schools observes that white middle‐class parents choose a predominantly white school – whose students are non‐ESL and have a second language choice of French – in a socially and ethnically mixed inner city neighbourhood, creating a stark imbalance in the student population of local neighbourhood schools. This paper examines parents' accounts of their choices, which they rationalise on the basis of linguistic competency and differentiation from multilingual others. We draw from Pierre Bourdieu's theory of language and symbolic power and Ghassan Hage's spatial theory of nationalist practice to understand the linguistic dimension of school choice rationalisation made by white middle‐class parents. In the context of these insights, we argue that the way anglophone white middle‐class parents choose their children's schools is intricately linked to active processes of reproducing a stratilingual society in Canada. 相似文献
84.
Since 2001, the issue of the low ratio of women faculty in universities has been prominent in Korea because of its negative
impact on female students and gender equality at the university level that has affected human resource development and utilization
at the national level. To address this issue, the Korean government developed and executed an education policy, the Policy
on Women Faculty Increase (PWFI) from 2004 to 2006. This paper investigated reactions to the PWFI and changes made as a result
of the policy in the conservative Korean higher education context. We found that although the PWFI has particularly contributed
to increasing the representativeness of women faculty in areas in which women faculty used to be rare, overall the PWFI has
not made significant improvements in most participating universities due to the lack of internal motives and drivers and effective
systems to support the policy. Recommendations for improvements in the policy are offered. 相似文献
85.
This integrative literature review synthesizes the concepts and process of organizational knowledge creation with theories of individual learning. The knowledge conversion concept (Nonaka & Takeuchi, 1995; Nonaka, Toyama, & Byosière, 2001) is used as the basis of the organizational knowledge creation process, while major learning theories relevant to working adult learners are newly synthesized into four types of individual learning processes: adaptive, generative, transformative, and reflective. The results suggest an integrative conceptual flow map of individual and organizational learning facilitated by culture and management system enablers. Implications for using this conceptual framework for practicing performance technology solutions are also discussed. 相似文献
86.
To test the hypothesis that biological motion perception is developmentally integrated with important social cognitive abilities, 12-month-olds ( N = 36) were shown a display of a human point-light figure turning to observe a target. Infants spontaneously and reliably followed the figure's "gaze" despite the absence of familiar and socially informative features such as a face or eyes. This suggests that biological motion displays are sufficient to convey rich psychological information such as attentional orientation and is the first evidence to show that biological motion perception and social cognitive abilities are functionally integrated early in the course of typical development. The question of whether common neural substrates for biological motion perception and analysis of gaze direction underlies the functional integration seen behaviorally is discussed. 相似文献
87.
Adam Winsler Margaret R. Burchinal Hsiao-Chuan Tien Ellen Peisner-Feinberg Linda Espinosa Dina C. Castro Doré R. LaForett Yoon Kyong Kim Jessica De Feyter 《Early childhood research quarterly》2014
Using nationally representative data from the ECLS-B, we examined children's outcomes and growth from 9 to 65 months as a function of language used in the home at 24 months (English only n = 7300; English and another language n = 1500; other language only n = 400). We also examined whether demographic variables moderated the effects of DLL status in predicting child outcomes. Results revealed substantial variation within the DLL population within and across language groups in immigration status, heritage country, child outcomes, and family socioeconomic risk. DLL status was associated with differential outcomes, gains over time, and processes in complex ways. Maternal birth outside of the U.S., child gender, and parental education moderated relations between home language and child outcomes. Use of the heritage language at home served as a protective factor for children of immigrant families for a few outcomes. Gender and parental education were more strongly associated with child outcomes among English-speaking households than among DLLs. 相似文献
88.
The purpose of this study was to investigate the relationship of students’ understanding of science knowledge, attitude and decision making on socio-scientific issues (SSI), especially on the issues of nuclear energy in Korea. SSI-focused instructions were developed to encourage students to understand and reflect on knowledge, attitude and decision making on nuclear energy in the current society. Eighty-nine students attended the instruction and participated in pre and post questionnaires to understand their understandings of nuclear energy. In this study, science knowledge was categorized into content and contextual knowledge, attitude consisted of images, safety, risk, potential, benefits and future roles, and decision making section included preference and alternative about lifetime extension of nuclear power plant. The results of questionnaires were analyzed by correlation, cross-tabulation and regression. As a result, while students’ understandings of science knowledge were significantly improved throughout the instruction, they maintained similar attitude and decision making on the issue. Regarding the relationship of the three domains, attitude showed some degree of connection to decision making whereas science knowledge did not show a significant relationship to decision making. This finding challenges SSI teaching in content-based science curriculum and classroom. Reflection and implications on the way of teaching SSI in the classroom were discussed further in this paper. 相似文献
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