运用"四步故事教学法"培养小学生英语语感

语感是人对语言的领悟感应能力,是语言训练到熟能生巧的表现,英语教学的支点便是语感。语感强的人理解力强,听别人说话抓得住要领,语言表达流畅得体。     

基于5M的智能生物制造人才培养体系构建——华东理工大学的探索与实践

新一轮科技革命和产业变革的加速演进为高校工科人才培养提出了新的挑战.为培养生物工程领域新工科人才,探索形成了了5M智能生物制造新工科人才培养体系,从课程体系设置、学科交叉融合、国际化人才培养、教研深度融合等方面开展了有益的探索与实践,为生物工程领域新工科创新人才培养提供借鉴.     

以校为本:院校研究的核心价值取向

对我国而言,院校研究是高等教育的一个新的研究领域、一种新的研究范式,开启了专门研究某所具体高等院校的新的实践活动形式。本文从院校研究的动因是学校自身的发展,院校研究的对象是具体的学校自身,院校研究的内容是本校实际问题,院校研究的主体是本校人员等四个方面来探讨、说明“以校为本”是院校研究的核心价值取向,以期为我国的院校研究提供一个新的视角。     

公文、志书文风共性浅析

公文、志书虽不属同一文体,但其文风有共性之处,本文试从"严谨、朴实、简洁、流畅"及略带文采几方面对此进行剖析.     

教育的终极目的——关注人的生存状态

通过对教育终极目的的认识,分析了多种关于教育终极目的的论点.揭示了这些论点具有共同的基础,即教育是一门生存的艺术,它的终极目的应为关注人的生存状态.     

我国小学生道德情感发展研究述评与展望

小学生道德情感发展的研究是德育心理学研究领域的重要组成部分之一.本文从研究工具、关键期、移情发展、道德情绪判断四个方面总结了我国10余年来在该领域的研究,阐述了研究存在的不足,并对研究的未来做了展望     

华县东阳西周墓地结构研究

东阳西周墓地可划分为不同族属的两类四个墓区,包含殷遗民与东阳主体族群,后者可能原为活动于甘肃东部地区的西土古族,或因灭商有功,于周初改封畿内,并被分赐以殷遗民.墓地内的墓葬按族属、等级分墓区而葬,表明血缘关系是其社会组织的基础,族群内与族群间的等级差异又体现了宗法等级制度及族群关系的政治等级化.其统治族群结合殷遗民的族...     

大众化过程中高等教育自学考试的作用和发展

我国高等教育已经实现了大众化。在大众化过程中,高等教育自学考试起到主力军的作用。在大众化条件下,高等教育自学考试向高等职业教育方向发展。目前这种趋势主要表现在开设应用技术型专业、推行双证书教育模式、突出就业功能、重视对毕业生的就业指导工作等方面。     

Replication,pathogenicity, and transmission of SARS-CoV-2 in minks

Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts, and transmits efficiently in minks via respiratory droplets; pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19. We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks. Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2.     

Injectable hybrid inorganic nanoscaffold as rapid stem cell assembly template for cartilage repair

Cartilage injuries are often devastating and most cannot be cured because of the intrinsically low regenerative capacity of cartilage tissues. Although stem-cell therapy has shown enormous potential for cartilage repair, the therapeutic outcome has been restricted by low survival rates and poor chondrocyte differentiation in vivo. Here, we report an injectable hybrid inorganic (IHI) nanoscaffold that facilitates fast assembly, enhances survival and regulates chondrogenic differentiation of stem cells. IHI nanoscaffolds that strongly bind to extracellular matrix (ECM) proteins assemble stem cells through synergistic 3D cell–cell and cell–matrix interactions, creating a favorable physical microenvironment for stem-cell survival and differentiation in vitro and in vivo. Additionally, chondrogenic factors can be loaded into nanoscaffolds with a high capacity, which allows deep, homogenous drug delivery into assembled 3D stem-cell-derived tissues for effective control over the soluble microenvironment of stem cells. The developed IHI nanoscaffolds that assemble with stem cells are injectable. They also scavenge reactive oxygen species and timely biodegrade for proper integration into injured cartilage tissues. Implantation of stem-cell-assembled IHI nanoscaffolds into injured cartilage results in accelerated tissue regeneration and functional recovery. By establishing our IHI nanoscaffold-templated 3D stem-cell assembly method, we provide a promising approach to better overcoming the inhibitory microenvironment associated with cartilage injuries and to advance current stem-cell-based tissue engineering.