城市图书馆服务农民工的问题及对策

论述城市图书馆在提高农民工综合素质方面具有的责任和义务,分析目前服务工作中存在的问题,并针对性地提出改正问题的对策,促使城市的公共图书馆能更优质、更有效地为农民工群体服务。     

FLT3 and NPM1 mutations in Chinese patients with acute myeloid leukemia and normal cytogenetics

Mutations of fms-like tyrosine kinase 3 (FLT3) and nucleophosmin (NPM1) exon 12 genes are the most common abnormalities in adult acute myeloid leukemia (AML) with normal cytogenetics. To assess the prognostic impact of the two gene mutations in Chinese AML patients, we used multiplex polymerase chain reaction (PCR) and capillary electrophoresis to screen 76 AML patients with normal cytogenetics for mutations in FLT3 internal tandem duplication (FLT3/ITD) and exon 12 of the NPM1 gene. FLT3/ITD mutation was detected in 15 (19.7%) of 76 subjects, and NPM1 mutation in 20 (26.3%) subjects. Seven (9.2%) cases were positive for both FLT3/ITD and NPM1 mutations. Significantly more FLT3/ITD aberration was detected in subjects with French-American-British (FAB) M1 (42.8%). NPM1 mutation was frequently detected in subjects with M5 (47.1%) and infrequently in subjects with M2 (11.1%). FLT3 and NPM1 mutations were significantly associated with a higher white blood cell count in peripheral blood and a lower CD34 antigen expression, but not age, sex, or platelet count. Statistical analysis revealed that the FLT3/ITDpositive group had a lower complete remission (CR) rate (53.3% vs. 83.6%). Survival analysis showed that the FLT3/ITD-positive/NPM1 mutation-negative group had worse overall survival (OS) and relapse-free survival (RFS). The FLT3/ITD-positive/NPM1 mutation-positive group showed a trend towards favorable survival compared with the FLT3/ITD-positive/NPM1 mutation-negative group (P=0.069). Our results indicate that the FLT3/ITD mutation might be a prognostic factor for an unfavorable outcome in Chinese AML subjects with normal cytogenetics, while NPM1 mutation may be a favorable prognostic factor for OS and RFS in the presence of FLT3/ITD.     

大学生不廉洁行为的心理分析与引导措施

保持廉洁之心是大学生廉洁教育的根本,是防腐治腐的需要,也是应对当前复杂形势的关键.高校思想政治教育者要注重对大学生廉洁心态的培养,引导大学生树立正确的心理动机,完善认知结构,提升实践能力.分析、归纳大学生的不廉洁行为,梳理造成大学生不廉洁行为的心理成因,从理想信念教育、廉洁心理培训、校园文化建设、高校工作机制、教师自身建设、学生自我教育等方面找出解决措施,从源头上减少大学生不廉洁行为的发生.     

New results on reachable sets bounding for delayed positive singular systems with bounded disturbances

This paper addresses the reachable sets bounding problem for time-delay positive singular systems subject to bounded disturbances. The time delays in the considered systems are assumed to be time-varying. Both invariant and time-varying singular systems are investigated in this paper. Existence conditions of componentwise ultimate bounds of the state vector of considered systems are derived and given in terms of the spectral abscissa of the system matrices, which are easy to be checked. The obtained results are demonstrated by two numerical examples.     

针对中国儿童的电视广告策略及效果

随着中国市场经济的发展,以及独生子女政策在中国的推行,孩子成为整个家庭生活的焦点。要对父母和孩子进行有效的商品推销,我们必须充分了解他们对广告的爱好及效果。有鉴于此,本文将报告一个大型研究的部分成果。     

How does the purchasing staff of an accident insurance organization seek information about treatment effectiveness?

Objectives: The objective is to study how the staff who purchase health care services for a large national government accident-compensation system seek information on treatment effectiveness, how they assess the quality of that information, whether they question the information sources they choose, and how familiar they are with the key concepts of evidence-based health care (EBHC).Method: Staff (22 out of 34) of the health purchasing division of the New Zealand Accident Compensation Corporation (NZ ACC) were interviewed using eight preformatted questions to which they could provide open and multiple answers. Responses were subsequently codified into typologies for quantitative analysis.Results: Most respondents report that they assess the effectiveness of a treatment by accessing published information (nonhuman sources), by consulting others (human sources), or by both means. They assess the quality of information mostly by consulting others, and the second-highest proportion of responses state that they do not know how to evaluate the quality of information. No clear preference emerges with respect to the types of information needed to determine the effectiveness of treatments. The majority of the staff believes they can access information needed to determine treatment effectiveness through the Internet or information databases such as MEDLINE. Although most said they understand the key concepts of EBHC, only five out of twenty-two were able to accurately describe them.Conclusions: The findings suggest that there is a low level of awareness among the staff of the NZ ACC regarding the use of evidence and understanding of the key concepts of EBHC. Many surveyed staff members lack the skills or training to directly question information about effectiveness of a treatment. They have little idea of the information required to determine the effectiveness of a treatment, and the majority appears to lack the skills to evaluate the health care literature.     

“图文博美”四馆协同服务之研究

公共图书馆、文化馆、博物馆和美术馆之间处于一种条块分割、分散管理的状态,很少开展具有一定深度和广度的交流与合作。文章分析了“图文博美”四馆开展协同服务的必要性和可行性,阐述了如何实现公共文化服务机构之间的协同服务,并介绍了江门地区文化场馆开展资源共享和联合服务的工作实践。     

利用迁移学习精准识别领域信息之探讨

[目的/意义]将从互联网大数据中无监督学习的结果迁移到目标领城,解决目标领城因学习样本有限而信息识别效果难以提升的问题。[方法/过程]使用以中文维基百科等数据预训练的RoBERTa模型进行迁移学习,将学习结果映射到目标领城后使用DPCNN对其进行聚合凝练,然后结合部分标注数据微调模型完成领域信息的精准识别。[结果/结论]在10个领城内与未进行迁移学习的模型及经典模型TextCNN对比,提出的模型均较大幅度优于对比模型,平均后的精确率绝对提高4.15%、3.43%,召回率绝对提高4.55%、3.44%,F1分数绝对提高4.52%.3.44%,表明利用网络大数据迁移学习可以显著提升目标领城的信息识别效果。     

基于卓越工程师培养的“机械工程测试技术”教学改革方案探讨

根据卓越工程师的培养要求,从实际出发,对“机械工程测试技术基础”课程教学进行了探索和改革,改革课堂教学内容,根据卓越班自身特点调整教课内容,设置团队创新任务;改革教学方式,结合工程案例,增强学生的实际分析问题解决问题的能力,引入国际化教学资源,让学生及时了解世界前沿技术;改革考核方式,全方位考核学生成绩。实践证明了教学改革的有效性。这一改革方法也可以在同类课程中推广。     

USING AN INTERNET ACTIVITY TO ENHANCE STUDENTS' AWARENESS OF AGE BIAS IN SOCIAL PERCEPTIONS

Seeking to extend curricula in a Psychology of Aging course, an online Internet test that assesses user's implicit attitudes was used as part of a learning activity to enhance students' awareness of age-bias in social perceptions. A pretest-posttest methodology examined the efficacy of this learning activity in three separate investigations. Overall, results suggest the learning activity increases students' awareness of cognitive biases in their perceptions of others. Further, self-enhancement motivation and alliance with a group that has suffered prejudice or discrimination were found to mediate bias ratings. The need to recognize age as a diversity issue and promote positive representations of older adults is discussed.