从比较的观点看印度伦理

古印度梵文史诗《摩诃婆罗多》所表述的伦理思想可以启示我们从一个包容、多元的角度看待西方伦理学中的三种主要理论:康德的道义论、功利主义的后果论和亚里士多德的德性伦理学.它们分别涉及到人的认知性、感受性和德性.这三种理论各有其支持的理由,也存在各自不同的困难.但它们之间不会完全相互排斥,而是和而不同.其中的每一个都不能充分地解释道德行为.只有基于责任、共同善的追求和美德这三者,才能做出一个完整的道德评价.     

Mucosal IgA & IL-1β in Helicobacter pylori Infection

Helicobacter pylori infection stimulates strong local inflammatory and specific IgA antibody production. The influence of antibodies on the bacterial colonization is not clear. Here, we have analysed the association between the mucosal IgA level and IL-1β in various manifestations of the infection seen endoscopically. Antral biopsies of 57 dyspeptic patients were taken for culture, histology and estimation of mucosal levels of anti-H. pylori IgA and IL-1β. Mean mucosal IgA level was higher in patients with normal mucosa compared to all other groups and lower IgA level was associated with higher bacterial density. IL-1β was higher in ulcer patients and suspicious malignancy group as compared to normal group and higher level of IL-1β was associated with higher grades of metaplasia. Present study indicates that local immunity seems to have a protective role against H. pylori infection and higher level of IL-1β induced by the pathogen may be associated with metaplasia and carcinogenesis.     

Diagnostic Role of Tumour Markers CEA, CA15-3, CA19-9 and CA125 in Lung Cancer

The aim of this study was to assess the diagnostic yield of the tumour markers carcinoembryonic antigen, carbohydrate antigen 15-3, carbohydrate antigen 19-9 and carbohydrate antigen 125, in serum and bronchoalveolar lavage fluid in a group of patients with bronchogenic carcinoma. Serum and bronchoalveolar lavage fluid samples were collected in a group of 90 patients with benign or malignant pulmonary diseases. After appropriate processing, tumour markers were determined by enzyme immunoassay. The diagnostic yields (sensitivity, specificity and predictive values) in each environment (serum and bronchoalveolar lavage fluid) were obtained by using "Receivers operating characteristic" curve. Determined individually, carcinoembryonic antigen, carbohydrate antigen 19-9 and carbohydrate antigen 125, showed the greatest diagnostic accuracy in bronchoalveolar lavage fluid. Carbohydrate antigen 15-3 did so in serum. Carcinoembryonic antigen was the most relevant marker in bronchoalveolar lavage fluid. For the factors evaluated in this study, determination of carcinoembryonic antigen, carbohydrate antigen 19-9 and carbohydrate antigen 125 in bronchoalveolar lavage fluid were clinically more useful markers in comparison with serum, although the latter may also be helpful in certain situations. Although there is no specific tumour marker for lung cancer, the combination of several can be used to diagnose most patients with lung cancer and also to rule out false positive and negative cases.     

Biotinidase deficiency—Diagnosis by enzyme assay and a follow-up study

A 3 month old male child was brought to the hospital with complaints of skin rashes, developmental delay, seizures, seborrheic dermatitis, alopecia and mild, acidosis. The child was subjected to a simple metabolic screening protocol. The result of the screening and the clinical symptoms provided an index pointing towards biotinidase deficiency., a rare autosomal recessive, inherited metabolic disorder. The enzyme was then assayed by using n-biotinylp-aminobenzoate as substrate and the diagnosis confirmed. A follow-up of the case indicated the efficacy, of biotin supplementation in biotinidase deficiency.     

逃跑的女孩

Ru Yun and San Hua were best friends. They had been the best of friends for almost half their lives, at about fifteen years of age. They went to the same school, took the same bus and shared the same interests. They were always together like a pair of Siamese twins. Nothing could separate them, not even their studies or their parents,     

Expanding the Nomological Network of Work Avoidance: Antecedents and Consequences Across Contexts

Abstract

Work avoidance, or the goal to reduce effort in an achievement context, is related to disengagement and may offer insight into disengaged students and employees. To shed light on this issue, we investigated the antecedents of work avoidance in academic and work contexts to distinguish it from mastery, performance-approach, and performance-avoidance goals. Two samples of employed college students (N?=?207, N?=?233) completed questionnaires about their jobs and in one sample about their introductory psychology class. Across both contexts, proposed antecedents of alienation, low need for achievement, and perceiving one’s competence needs as not being met predicted work avoidance. Work avoidance also accounted for additional variance when combined with achievement goals to predict citizenship behaviors, perceiving work/classwork as meaningless and wanting to leave/quit.