黄芪成分F_3新制剂对胃癌细胞株的抑制作用

[目的]观察黄芪成分F3新制剂对胃癌(BGC-823)细胞株体外细胞生长、抑制作用.[方法]利用基因组DNA电泳,流式细胞仪检测细胞凋亡.[结果]基因组DNA电泳出现“梯形”条带;流式细胞仪分析出现低于G1期DNA含量的亚二倍体凋亡率.[结论]黄芪成分F3新制剂对胃癌细胞有明显的抑制作用.     

Towards a Comprehensive Account of Effective Thinking

Due to its strong focus on reasoning and argumentation, critical thinking lacks the breadth required of a comprehensive account of higher order thinking. In particular, critical thinking does not promote reflection on the underlying problems or situations that people think about. This paper reviews various proposed additions to and reorientations of the critical thinking paradigm. It presents a conceptual framework that encompasses the most promising extensions as topics in a broadened account of higher order thinking. This account can be understood as an elaboration of problem solving along two dimensions: Problem types, which are generic thinking situations; and problem solving functions, which are generic thinking tasks. The proposed topic-level account of higher order thinking offers a greatly enlarged view of what should be taught in general thinking skills programs.     

Diarrhea Management Training in Early Childhood Settings

This study addresses the health of young children and how to safely and effectively care for children with diarrhea in the home and in early child care settings. A baseline survey showed the prevalence of oral rehydration solution (ORS) usage at last diarrhea bout to be low. An educational workshop was developed to train parents and child care professionals on how to properly manage young children with diarrhea and reduce the risk of diarrhea spread at home and in early childhood settings. Specific intervention activities are discussed and program activities, including specially designed materials for mixing homemade ORS are described. A comparison of pre- and postintervention data indicates substantial gains in knowledge among both urban and rural populations. Implications of research findings are discussed along with suggestions for future research.     

The Inclusion of Informal Environments in Science Teacher Preparation

Journal of Science Teacher Education -     

The vicissitudes of measurement: a confirmatory factor analysis of the Emotional Autonomy Scale

This study examined the factor structure of the Emotional Autonomy Scale (EAS) as proposed by Steinberg and Silverberg. Participants were from three independent samples of adolescents in grades 6 (n = 1,842), 8 (n = 1,769), and 10 (n = 1,232), with each sample consisting of three ethnic groups: African American, European American, and Mexican American. None of the confirmatory factor analyses for these samples supported the factor structure proposed by Steinberg and Silverberg. From the three models tested, the EAS is best described by the four originally proposed factors, combined with two method factors, one consisting of the positively worded scale items and one consisting of the negatively worded scale items. Results show that the EAS exhibits poor construct validity and behaves quite differently for the different grade and ethnic groups. The strong impact of method variance on the factor structure is discussed. Although various alternative solutions to the psychometric problems in the EAS are proposed, the most credible solution may be to reexamine the conceptual foundations of emotional autonomy and develop better measures of those concepts for adolescents.     

Modifying the distribution of attention in infants

In three experiments, the distribution and malleability of infant visual attention were studied in 5-month-olds (N = 72) while they inspected large geometric designs. In Experiment 1, we established that infants maintained their distribution of attention from a pretest to a familiarization phase. We also replicated and extended our previous findings that infants who examined targets with briefer, more numerous looks and shifts-short lookers-had novelty scores above chance, whereas long lookers demonstrated chance responding. In Experiment 2, different portions of the display were successively illuminated with red light. This manipulation induced long lookers to scan like short lookers during familiarization; they then showed novelty scores well above chance. A third experiment ruled out the simple presence of a red light as the source of this effect. In sum, then, these results suggest that the distribution of attention is malleable, and that a broader distribution of attention, as reflected in briefer and more numerous looks and shifts, can improve processing.     

Negotiating the transition to middle school: the role of self-regulatory processes

The present research examined the role of maladaptive self-regulatory beliefs as vulnerability factors for academic and emotional difficulties during the transition to middle school. A short-term longitudinal design was employed to follow two groups of early adolescents: 187 adolescents who experienced a school transition between the fifth and sixth grades, and 142 adolescents who did not experience a school transition between the fifth and sixth grades. Adolescents completed measures of perceptions of academic control and importance of academic success, experience of chronic academic strain, daily school hassles, and depressive symptoms. Teachers reported on students' academic engagement, including levels of helpless behavior, effort, and academic performance. Consistent with the proposed model of self-regulation, maladaptive self-regulatory beliefs (i.e., decreased perceptions of academic control and importance) predicted individual differences in perceived school-related stress and depressive symptoms over the course of the middle school transition, but were not associated with academic and emotional difficulties in adolescents who remained in a stable school environment. Moreover, a self-regulatory sequence was identified proceeding from maladaptive self-regulatory beliefs, to academic disengagement, to enhanced perceptions of school-related stress, to depressive symptoms. This study bridges prior theory and research concerning the psychological impact of normative developmental transitions, the developmental context of depression, and the associations among self-regulatory beliefs, achievement-related behavior, and emotional experience.     

论财政体制改革对高等教育的影响

10多年来,我国财政体制逐步向公共财政转变,一是财政管理体制发生了变化,二是建立健全了预算管理制度。财政体制改革各项措施的实施,对高等教育产生了极大的影响,主要体现在:财政投入责任从中央转移到地方政府;高等教育投入机制出现"缺位";财政性高教经费投入不足,历史欠帐多等方面。