创建E-Learning系统教学模式初探

本文在对现行教学模式的弊端进行分析的基础上,提出指导E-learning系统教学模式的教学理论,分析了建构E-learning系统的教学环境,并具体指出研究型学习模式、案例研习模式、发现式学习模式、资源型学习模式、协作式学习模式、虚拟教学模式等具有较强实用价值的E-learning系统的教学模式。     

发酵后处理方法研究(Ⅰ)——谷氨酸发酵液除菌体条件的探讨

本文系统探讨了脱乙酰甲素絮凝沉淀谷氨酸发酵液中菌体的性能、絮凝作用的最适pH、最适温度、絮凝剂最适用量、菌体等电点以及味精发酵液中菌体除去等问题。     

Homoharringtonine induces apoptosis of endothelium and down-regulates VEGF expression of K562 cells

Homoharringtonine (HHT) has currently been used successfully in the treatment of acute and chronic myeloid leukemias and has been shown to induce apoptosis of different types of leukemic cells in vitro. Emerging evidence suggests that angiogenesis may play an important role in hematological malignancies, such as leukemia. How ever, whether HHT can relieve leukemia by anti-angiogenesis is still unknown. We investigated the anti-angiogenesis potential of HHT with the human umbilical vein endothelial cell line (ECV304) and leukemic cell line (K562) in vitro. Cellular proliferation was determined by MTT assay and apoptosis was analyzed by flow cytometry. The mRNA expression of vascular endothelial growth factor (VEGF) was assessed by RT-PCR and VEGF protein production was detected by Western blot. Inhibition of cell proliferation and induction of apoptosis by HHT were discovered in ECV304 cells, and appeared in a dose- and time-dependent manner. Also, treatment with HHT caused down-regulation of VEGF mRNA expression in K562 cells in similar dose- and time-dependent manner and inhibition of VEGF protein production in K562 cells in response to the enhancing concentration of HHT. The results demonstrated that HHT could also induce apoptosis in endothelium and down-regulate VEGF expression in K562 cells. In conclusion, we believe HHT has anti-angiogenesis potential and speculate that HHT might exert its anti-leukemia effects via reduction of angiogenesis.     

高等职业教育投资效益的经济学分析

运用经济效益理论，对高等职业教育的投资效益指标进行了分析，并总结出提高高等职业教育投资效益的途径。     

虫媒登革病毒的研究——Ⅱ.登革病毒非结构蛋白NS1的纯化、鉴定及其在临床检测应用

本文从纯化Den2 NS1,Mab入手,自制了Mab亲和层析系统,从感染Den2的细胞膜中,分离提取了天然的Den 2 NS1双体,比较其NGC株与我国地方株(H-87)NS1的理化性质及组成,并对某些重要的生物学性质进行了综合性研究。同时,利用上述研究结果建立了检测DF病人血清特异NS1抗体的新方法,探索其协助临床诊断及研究的可能性。     

具有最少采样点的圆度误差测量研究

建立了采样点均匀分布情况下，圆度误差测量采样点数量与测量极限误差之间的定量关系数学模型。根据所得数学模型，对测量坐标值原则下给定圆度误差检测对象的采样点进行规划，求得具有最少采样点的测量方法，并给出了测量实例，对数学模型进行了验证。     

高职高专师范专业《现代教育技术》公共课教学实践探讨

提高师范生应用教育技术的能力是基础教育课程改革的需求。高职高专师范专业开设《现代教育技术》公共必修课,要以培养学生的教育技术能力为重点,区别教育技术培养能力与信息技术培养,克服课程中的技术化倾向。以《中小学教师教育技术能力标准》为依据,建立评价体系。     

The effects of college students’ positive thinking,learning motivation and self-regulation through a self-reflection intervention in Taiwan

This quasi-experimental study examined the effects of a self-reflection intervention on college (college in this article refers to university-level education) students’ positive thinking, learning motivation and self-regulation in Taiwan. One hundred and two college students were selected to participate in an 18-week intervention forming the experimental group (EG) which emphasized providing main lecture, role-play, self-reflection activity, group discussion and group work. Another 179 college students from two other courses were selected as a comparison group. This study showed that supportive, resourced discussion with peers and instructor, self-reflection activities and assignment as a facilitative agent improved the EG students’ positive thinking, learning motivation and self-regulation. In addition, three structural equation models revealed that positive thinking had a strong and direct relation to Taiwanese college students’ pretest learning motivation (β?=?.85) and self-regulation (β?=?.77); learning motivation had a strong and direct relation to students’ pretest positive thinking (β?=?.86) and self-regulation (β?=?.81); and self-regulation had a strong and direct relation to students’ pretest positive thinking (β?=?.83) and learning motivation (β?=?.86). Instructional implications and research recommendations are discussed.     

Investigation of iodine concentration in salt,water and soil along the coast of Zhejiang,China

Objective: We aim to describe the environment iodine concentration in salt, water and soil along Zhejiang Province coast in the China foreland. It will be helpful for us to judge whether this area is insufficient in iodine and universal iodized salt is necessary or not. Methods: We collected iodized salt samples, drinking water samples (tap water in the towns, and well water or spring water in the villages), water samples from different sources (ditches, lakes, rivers) and soil samples through random sampling in June, 2005. Salt, water and soil iodine was detected by arsenic-cerium redox method. Statistical analysis was expressed as mean±SEMby Windows SPSS 13.0. Results: (1) The iodine concentration in salt was 27.9±4.33 mg/kg (n=108). (2) Seventy-five water samples were collected. The water iodine value was 0.6～84.8 μg/L (mean of 11.66 μg/L). The watershed along the Qiantang River has significantly higher iodine content than the water in Lin'an in mountain area (P＜0.01). The iodine content and mean iodine content of tap water, well or spring water and natural water sources were 4.30±2.43 μg/L (n=34), 23.59±27.74 μg/L (n=19)and 12.72±10.72 μg/L (n=22) respectively. This indicated that among environmental water sources, the ditch iodine content was the highest with river water iodine being the lowest (P＜0.01). (3) Soil iodine value was 0.11～2.93 mg/kg (mean of 1.32 mg/kg).Though there was no statistical difference of soil iodine in different districts (P=0.131), soil iodine content correlated positively with water iodine content. Conclusion: Iodine concentration in salt accords with national policy of adding iodine in salt. Foreland has more iodine in water than mountain area. The data reflected that water and soil iodine in foreland area was not high, which suggests universal iodized salt should be necessary. Environment iodine has relatively close association with pollution.     

关于非游荡点集的等价描述

非游荡点集为拓扑动力系统中所涉及到的一类重要点集。在《动力系统基础》的基础上对非游荡点作进一步描述,获得几个有用的结果。