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61.
In the presentclimate libraries have to adopt a business approach to funding submissions; detailed managementinformation must be produced in support of expenditure and to ensure that the services are cost-effective. In addition to the grant from its parent body (the Faculty of Clinical Medicine,University of Oxford), the Cairns Library obtains funding from five other bodies, includingNational Health Service Hospital Trusts. The Cairns Library has introdu ies anduser education. The costs for each package have been apportioned to the funding bodies on thebasis of the number of registered users from each body.  相似文献   
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This study reports on several specific neurocognitive process predictors of reading outcomes for a sample of 278 children with reading disabilities. Three categories of response (i.e., poor, average, and good) were formed via growth curve models of six reading outcomes. Two nested discriminant function analyses were conducted to evaluate the predictive capability of the following models: (a) an intervention and phonological processing model that included intervention group, phonological awareness, and rapid naming and (b) an additive cognitive neuropsychological model that included measures of memory, visual processes, and cognitive or intellectual functioning. Over and above the substantial explanatory power of the base model, the additive model improved classification of poor and good responders. Several of the cognitive and neuropsychological variables predicted degree of reading outcomes, even after controlling for type of intervention, phonological awareness, and rapid naming.  相似文献   
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Zebra finch song behavior is sexually dimorphic: males sing and females do not. The neural system underlying this behavior is sexually dimorphic, and this sex difference is easy to quantify. During development, the zebra finch song system can be altered by steroid hormones, specifically estradiol, which actually masculinizes it. Because of the ease of quantification and experimental manipulation, the zebra finch song system has great potential for use in undergraduate labs. Unfortunately, the underlying costs prohibit use of this system in undergraduate labs. Further, the time required to perform a developmental study renders such undertakings unrealistic within a single academic term. We have overcome these barriers by creating digital tools, including an image library of song nuclei from zebra finch brains. Students using this library replicate and extend a published experiment examining the dose of estradiol required to masculinize the female zebra finch brain. We have used this library for several terms, and students not only obtain significant experimental results but also make gains in understanding content, experimental controls, and inferential statistics (analysis of variance and post hoc tests). We have provided free access to these digital tools at the following website: http://mdcune.psych.ucla.edu/modules/birdsong.  相似文献   
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This paper presents a novel sensor technology to deduce the dynamics of a bowling ball. The sensor, a miniature wireless inertial measurement unit (IMU), incorporates MEMS accelerometers and angular rate gyros, a microcontroller, a low power RF transceiver, and a rechargeable battery. When embedded in a bowling ball, the IMU transmits the acceleration and angular velocity data that define the dynamics of the ball starting with the bowler’s delivery and its motion in the lane. Example results from professional bowlers illustrate how this technology can be used to assess bowler skill and ball performance. For instance, the IMU accurately measures the spin dynamics of the ball which are crucial to develop the ball “hook.” An analysis of ball dynamics in the lane is distilled to a measurable “hook potential” metric for further assessing bowler skill. Finally, the sensor presented herein is believed to be the world’s smallest, wireless IMU. This highly miniaturized and wireless design will enable parallel training systems for many sports, including basketball, baseball, crew, cricket, golf, fly fishing, soccer, softball, tennis, rowing, among others.  相似文献   
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To understand the experiences and views of childbearing women in the United States and trends over time, Childbirth Connection carried out the third national Listening to Mothers survey among 2,400 women who gave birth in U.S. hospitals to a single baby from mid-2011 to mid-2012 and could participate in English. A follow-up survey directed to the same participants explored postpartum experiences, in depth and well into the second year after birth; views about maternity care; and some additional pregnancy and birth items. Harris Interactive conducted the surveys using a validated methodology that includes data weighting to ensure that results closely reflect the target population. The follow-up survey was reported in Listening to Mothers III: New Mothers Speak Out.  相似文献   
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It is argued that online discussion is a useful tool for creating opportunities for learning in teacher education. In a project designed to improve the practicum in rural areas, researchers placed pre-service teachers (PSTs) in two different moderated online discussion forums: an unstructured personal blog space and a structured threaded discussion forum where discussion topics guided them to reflect on their practicum experiences in relation to theoretical components of their studies. Findings indicated a marked difference in the contributions made to each form of online discussion with significantly greater participation in the unstructured blog format. Using Kreber and Cranton’s hierarchy of reflection, analyses of both forums found that PSTs rarely engaged in high-level reflection. Examination of lecturer involvement in the forums suggests that their contributions did not sufficiently encourage PSTs towards optimum critical reflection. These results leave the researchers considering ways in which the practicum experience can better promote reflective practice in this crucial, component of teacher education.  相似文献   
69.
The majority of eukaryotic genes produce multiple mRNA isoforms with distinct 3′ ends through a process called mRNA alternative polyadenylation (APA). Recent studies have demonstrated that APA is dynamically regulated during development and in response to environmental stimuli. A number of mechanisms have been described for APA regulation. In this review, we attempt to integrate all the known mechanisms into a unified model. This model not only explains most of previous results, but also provides testable predictions that will improve our understanding of the mechanistic details of APA regulation. Finally, we briefly discuss the known and putative functions of APA regulation.  相似文献   
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