加大工作创新力度 为印刷业发展助力——记自治区印刷协会换届选举大会

2011年3月10日,自治区印刷协会召开了第五次会员代表大会工作会议。自治区新闻出版局党组书记石永强,局长米吉提·卡德尔,副局长王跃平、古力先·吐拉洪、纪检组组长刘树新、副局长赛力克·巴勒夏提及自治区科协领导和学会学术部负责人出席会议。全疆各印刷企业法人代表共计175人参加了会议。会议由第四届印刷协会副理事长兼秘书长、自治区新闻出版局印刷发行管理处处长刘诚主持。     

Searching for randomised controlled trials and clinical controlled trials in Thai online bibliographical biomedical databases

Background: Thailand is a poor but highly literate country in South‐East Asia with over 60 million people. A lot of biomedical research is undertaken but dissemination is limited. Objectives: To identify relevant Thai bibliographic databases and investigate accessibility, functionality and content, particularly in relation to randomised controlled trials (RCTs) and clinical controlled trials (CCTs). Methods: A systematic search for institutions productive of research and the databases in their libraries. Search each accessible database in both Thai and English, recording the functionality and content. Assess accessibility of the retrieved RCTs or CCTs by comparing to Pub Med holdings. Results: We found 32 different databases (29 accessible in UK) of various sizes, coverage and functionality but many with unique records of RCTs and CCTs (total, n = 781). Two hundred and nine of 781 trials were accessible on Pub Med (27%). However, 641 of the 781 trial records contain text in both English and Thai (82%) and 112 records were solely English (14%). Conclusions: Those undertaking comprehensive searches for RCTs/CCTs should, in addition to a Pub Med , search the Thai Medical Index and Thai Index Medicus databases, and the Khon Kaen University Library Catalogue.     

GIS空间数据在地图制图中的应用思路研究

地理信息系统（GIS）是地理学、地图学等在信息化时代发展的新的理论技术体系,笔者基于多年从事地图制图的工作经验,以GIS空间数据与地图制图的融合技术为研究对象,分析了GIS空间数据在地图制图中的应用思路,探讨了空间数据与地图制图融合生产系统的应用思路。     

新疆山区低层冰云云水资源初探

本文采用NASA地球观测系统（EOS）的＂云与地球辐射能量系统（CERES）＂2003年至2007年CERES SSF Aqua MODIS Edition 2B/2C云资料,以新疆天山、阿尔泰山和昆仑山三大山区为主要研究对象,通过考察云水柱含量和粒子有效直径,对低层冰云云水资源时空分布特征进行了初步分析。结果表明,无论是冰云云水柱含量还是冰云粒子有效直径,多年平均的高值区集中在天山和昆仑山;盆地及其沙漠地区则是低值区,阿尔泰山处于高值区和低值区的过渡带上。新疆地区的低层冰云云水柱含量的多年平均值在（70～135）g/m2之间,冰云粒子有效直径的多年平均值在37～48μm之间。三大山区附近城市的低层云冰云云水柱含量多年平均值较高,部分城市如伊宁、乌鲁木齐、塔城、博乐达（100～150）g/m2。按季节来分析,三大山区多年平均的冰云云水柱含量夏季最高,冬季最低,春季和秋季较接近,而冰云粒子有效直径的季节变化各山区不相同。     

The paraoxonase 1, 2 and 3 in humans

The paraoxonase gene family in humans includes three members: PON1, PON2 and PON3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (VLDL) and postprandial chylomicrons. PON1 possess organophosphatase, arylesterase and lactonase activity and it hydrolyzes many different substrates. It is also known that PON1 may have antiatherogenic function. Compared to the PON1, PON2 and PON3 are much less studied and described. PON2 is ubiquitously expressed intracellular protein, while PON3 is bound to HDL, like PON1. The both enzymes possess antioxidant properties.     

浅谈新技术在冷却塔系统中的运用

工业生产或冷却工艺过程中产生的废热,一般要用冷却水来导走。冷却塔的作用是将挟带废热的冷却水在塔内与空气进行热交换,使废热传输给空气并散人大气。结合实际,重点介绍了新技术在冷却塔系统中的运用。     

Superior oxygen and glucose supply in perfusion cell cultures compared to static cell cultures demonstrated by simulations using the finite element method

Oxygen and glucose supply is one of the important factors for the growth and viability of the cells in cultivation of tissues, e.g., spheroid, multilayered cells, and three-dimensional tissue construct. In this study, we used finite element methods to simulate the flow profile as well as oxygen and glucose supply to the multilayered cells in a microwell array chip for static and perfusion cultures. The simulation results indicated that oxygen supply is more crucial than glucose supply in both static and perfusion cultures, and that the oxygen supply through the wall of the perfusion culture chip is important in perfusion cultures. Glucose concentrations decline with time in static cultures, whereas they can be maintained at a constant level over time in perfusion cultures. The simulation of perfusion cultures indicated that the important parameters for glucose supply are the flow rate of the perfusion medium and the length of the cell culture chamber. In a perfusion culture chip made of oxygen-permeable materials, e.g., polydimethylsiloxane, oxygen is hardly supplied via the perfusion medium, but mainly supplied through the walls of the perfusion culture chip. The simulation of perfusion cultures indicated that the important parameters for oxygen supply are the thickness of the flow channel and the oxygen permeability of the walls of the channel, i.e., the type of material and the thickness of the wall.     

Scaffold fabrication in a perfusion culture microchamber array chip by O(2) plasma bonding of poly(dimethylsiloxane) protected by a physical mask

Extracellular matrix (ECM) proteins are required for cell culture. In this paper, we report the use of O(2) plasma bonding to fabricate a perfusion culture microchamber array chip with identical-size ECM spots in the isolated microchambers. The chip was fabricated by assembly of two poly(dimethylsiloxane) (PDMS) layers, a microfluidic network layer, and an ECM array layer, which were aligned and then bonded by O(2) plasma oxidation with protection of the ECM microarray with a physical mask made from PDMS. We successfully cultivated Chinese hamster ovary K1 cells in the microchambers with fibronectin. In the fibronectin microchambers, the cells adhered and extended after 12 h of static culture and then grew over the course of 1 d of perfusion culture.     

Intravascular haemolysis during prolonged running on asphalt and natural grass in long and middle distance runners

Surface features such as uneven playing surfaces, low impact absorption capacity and inappropriate friction/traction characteristics are connected with injury prevalence whereas force impact during foot strike has been suggested to be an important mechanism of intravascular haemolysis during running. We aimed to evaluate intravascular haemolysis during running and compare the effect of running on two different types of surfaces on haemolysis. We selected two surfaces (asphalt and grass) on which these athletes usually run. Participants were randomly assigned to group A (asphalt) or group B (grass) with 10 athletes in each group. Each athlete completed one hour of running at the calculated target heart rate (60-70%). Venous blood samples were collected before and immediately after running. We measured unconjugated bilirubin (UBR) (mg · dl(-1)), lactate dehydrogenase (LDH) (μ · ml(-1)), haemoglobin (g · l(-1)) and serum ferritin (ng · ml(-1)) as indicators of haemolysis. Athletes who ran on grass demonstrated an increase in the haematological parameters (UBR: P < 0.01, LDH: P < 0.05) when compared to athletes who ran on asphalt (UBR: P < 0.05, LDH: P = 0.241). Our findings indicate that intravascular haemolysis occurs significantly after prolonged running. Furthermore, we conclude that uneven grass surface results in greater haemolysis compared to asphalt road.     

The effect of a supported exercise programme in patients with newly diagnosed Type 2 diabetes: a pilot study

The aim of this study was to examine the effectiveness of either a standard care programme (n = 9) or a 12-week supported exercise programme (n = 10) on glycaemic control, β-cell responsiveness, insulin resistance, and lipid profiles in newly diagnosed Type 2 diabetes patients. The standard care programme consisted of advice to exercise at moderate to high intensity for 30 min five times a week; the supported exercise programme consisted of three 60-min supported plus two unsupported exercise sessions per week. Between-group analyses demonstrated a difference for changes in low-density lipoprotein cholesterol only (standard care programme 0.01 mmol · L(-1), supported exercise programme -0.6 mmol · L(-1); P = 0.04). Following the standard care programme, within-group analyses demonstrated a significant reduction in waist circumference, whereas following the supported exercise programme there were reductions in glycosylated haemoglobin (6.4 vs. 6.0%; P = 0.007), waist circumference (101.4 vs. 97.2 cm; P = 0.021), body mass (91.7 vs. 87.9 kg; P = 0.007), body mass index (30.0 vs. 28.7 kg · m(-2); P = 0.006), total cholesterol (5.3 vs. 4.6 mmol · L(-1); P = 0.046), low-density lipoprotein cholesterol (3.2 vs. 2.6 mmol · L(-1); P = 0.028), fasting β-cell responsiveness (11.5 × 10(-9) vs. 7.0 × 10(-9) pmol · kg(-1) · min(-1); P = 0.009), and insulin resistance (3.0 vs. 2.1; P = 0.049). The supported exercise programme improved glycaemic control through enhanced β-cell function associated with decreased insulin resistance and improved lipid profile. This research highlights the need for research into unsupported and supported exercise programmes to establish more comprehensive lifestyle advice for Type 2 diabetes patients.