在雨中飞奔

~~在雨中飞奔@小Q     

星座9月运势

从本月起,我们特地请来国外星座专家,为您提供每月星座运势,还可以顺便学习星座英语哦！     

星座10月运势

本月主打星座——处女座（8．24～9．23）。处女座是追求完美的星座,做事一丝不苟,有强烈的批判精神。极度厌恶虚伪与不正当的事。谦虚、理性、高智商、高财商的处女座往往是优秀的主管,能够在企业中起带头作用。     

Characterization of a bioflocculant from a newly isolated Vagococcus sp. W31

INTRODUCTION Bioflocculation is a dynamic process resulting from the synthesis of extracellular polymer by living cells. Since flocculation in microbial system was first reported by Louis Pasteur (Salehizadeh and Sho-jaosadati, 2001), bioflocculation has been investi-gated extensively and a correlation was established between the accumulation of extracellular biofloccu-lants and cell aggregation (Tenney and Verhoff, 1973). Bioflocculants are essentially polymers pro-duced by microorgan…     

Science Letters：IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1

Insulin-like growth factor binding-protein-7 （IGFBP7） was obtained from our previous colonic adenocarcinoma （CRC） and normal mucosa suppression subtraction hybridization （SSH） cDNA libraries. By RT-PCR and immunohistochemistry, we found that IGFBP7 was overexpressed in CRC tissue compared to normal tissue. However, our in vitro experiments performed in 10 CRC cell lines showed that IGFBP7 expressed only in SW480 and Caco2 cell lines, which implied an underlying reversible regulatory mechanism. Using methylation-specific PCR （MSP） and bisulfite sodium PCR （BSP）, we found that its expression was associated with DNA hypomethylation of exonl. This was further supported by the in vitro study which showed restored IGFBP7 expression after demethylation agent 5-aza-2＇-deoxycytidine treatment. Correlation analysis between IGFBP7 expression and prognosis indicated that overexpression of IGFBP7 in CRC tissue correlated with favourable survival. Investigation of the functional role of IGFBP7 through transfection studies showed that IGFBP7 protein could inhibit growth rate, decrease colony formation activity, and induce apoptosis in RKO and SW620 cells, suggesting it a potential tumor suppressor protein in colorectal carcinogenesis. In conclusion, our study clearly demonstrated that IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis and its expression is associated with DNA hypomethylation of exon 1.     

夏日肌肤“驻”水秘笈Let''''s go masking

夏季的到来,千万不可让猛烈的阳光肆虐肌肤,令其变得干燥及出现恼人的黑斑。除了涂用美白乳霜外;要得到最显著而即时的效果,便是选用具美白成分的面膜。要加强美白效果,便要选择含多种维他命及纯天然矿物质成分的面膜,例如含有脂溶性维生素C,有助排除及分解黑色素的积聚,防止黑斑的产生,改善暗哑的肤色,并能为肌肤提供适当的润泽。     

被埋藏的爱

Where can we go, if we're lost in the air? What can we find, if there' s nothing there? Who can we talk to,if we're surrounded by hate? When can we walk freely up to that Golden Gate? The answer, my friend, is not to go high, Nor to go across. No, the answer,my friend,is buried deep down.     

Assessment of Containment Structures Against Missile Impact Threats

In order to ensure the highest safety requirements, nuclear power plant structures (the containment structures, the fuel storages and transportation systems) should be assessed against all possible internal and external impact threats. The internal impact threats include kinetic missiles generated by the failure of high pressure vessels and pipes, the failure of high speed rotating machineries and accidental drops. The external impact threats may come from airborne missiles, aircraft impact, explosion blast and fragments. The impact effects of these threats on concrete and steel structures in a nuclear power plant are discussed. Methods and procedures for the impact assessment of nuclear power plants are introduced. Recent studies on penetration and perforation mechanics as well as progresses on dynamic properties of concrete-like materials are presented to increase the understanding of the impact effects on concrete containment structures.     

How Does the Intertidal Sipunculid Phascolosoma Arcuatum Detoxify Hydrogen Sulphide in a Lack of Oxygen

Inmanymarinesediments,considerableconcentrationsofhydrogensulphidearefound[1].Hydrogensulphideistoxictoanimalsduetothestrongbutreversible-bindingtocytochromeaa3andtheconsequentinhibitionofaerobicmetabolism[2].However,itcannotexcludeanimalinthesemarinebiotopes.Severalinvertebrates,similartothemammalianliver,canoxidizesulphidetonon-toxicthiosulphateandsulphate[1].VolkelandGrieshaber[3]reportedthatthesipunculidSipunculusnudus,whichinhabitsarelativelysandysubstratum,oxidizessulphidetothiosulphate…     

Left-handed materials in magnetized metallic magnetic thin films

INTRODUCTION Veselago (1968) showed that if both the permit- tivity ε and the magnetic permeability μ of a material are negative, the propagation direction of an elec- tromagnetic (EM) wave will be opposite to its energy flow direction. Such media are called left-handed materials (LHMs) since the electric field E, magnetic field H, and wave vector k in these media form a left-hand triplet of vectors, instead of a right-hand triplet observed in conventional materials. For a long time, …