The impact of exercise training on the lipid peroxidation metabolomic profile and respiratory infection risk in older adults

Aging is associated with oxidative stress that may increase susceptibility to respiratory infections (RIs). We aimed to assess the impact of exercise training on the risk of RIs in older adults and on a targeted metabolomic profile of stress oxidative lipid peroxidation-related metabolites. Methods: In an 8-month clinical trial, 38 participants over 60 years of age were allocated to an exercise group (EG), in which participants underwent 90-min training sessions three times/week(n?=?20), or a control group (CG), in which participants maintained daily physical activities(n?=?18). Daily respiratory symptoms and RIs number and severity were collected. Serum by-products were assessed by comprehensive two-dimensional gas chromatography coupled to mass spectrometry with time of flight analyzer. Serum metabolomic profiling comprised 76 metabolites (alcohols, aldehydes, alkanes, and ketones). Principal components analysis and ANOVA-simultaneous component analysis were used to evaluate the metabolomic profile change. Results: The odds ratio of RIs for the EG was 2.0 CI 95% [0.2;25]. The incidence of RIs was 47% [23;70] in the EG vs. 44%[12;77] in the CG. The metabolomic profiling showed that alkanes and aldehydes classes differed between the EG and the CG before and after intervention. A calibration model showed a relation between the metabolites from four main classes (ketones, alcohols, alkanes and aldehydes) and the prediction of the number of RIs. Conclusion: Moderate exercise training, in older adults, compared with no exercise in controls, did not show a difference in the risk of RIs. A pattern of lipid peroxidation was associated with the number of RIs.     

Low-dose exercise training does not influence cardiac autonomic control in healthy sedentary men aged 55-75 years

The purpose of this study was to evaluate the effects of a realistic, feasible, and commonly used fitness training programme on cardiac autonomic control in 14 sedentary men aged 62.0 +/- 6.1 years (mean +/- s). All participants performed a one-year fitness training programme in which training intensity and frequency were specifically chosen to be compliant for the majority of the participants (2-3 sessions per week at moderate intensity). At the same time, a reference group consisting of 15 sedentary age-matched men (age 64.2 +/- 6.5 years) did not change their habitual physical activity. Measurements were performed before and after the training intervention. Cardiac autonomic control was inferred from resting values (supine and standing) of heart rate variability (HRV) computed in the frequency domain over 10-min intervals. Endurance capacity was evaluated during a maximal incremental bicycle ergometer test. In spite of an increase in peak oxygen consumption (VO2peak) by 6.4% after training, heart rate in the training group remained unchanged at rest and at the same metabolic demand. No changes in resting parameters of HRV were shown for either groups or positions. Results from this study provide no evidence of a clinically meaningful increase in the vagal modulation to the sinus node at rest after one year of low-volume and moderate-intensity fitness training in men aged 55-75 years.     

A sociometric comparison of mainstreamed,orthopedically handicapped high school students and nonhandicapped classmates

This study explored the sociometric status of orthopedically handicapped (OH) high school students in mainstreamed classrooms. Twenty-nine students in mainstreamed classrooms (e.g., spina bifida or other paralysis, cerebral palsy, muscular dystrophy) were compared with randomly selected classmates on the Peer Rating Scale (PRS), a class-administered sociometric scale. The OH group received significantly higher scores on 2 of 12 PRS factors, as well as directionally higher scores on 8 others. These were interpreted as reflecting either genuine liking and admiration for mainstreamed OH high school students or, alternatively, a “defensive” inability on the part of peers to express base-rate negative feelings toward the orthopedically handicapped. Recommendations for future research are made.     

A comparative study of the self-esteem,sociometric status,and insight of referred and nonreferred school children

Elementary-grade children referred to a school-based mental health program were compared with randomly selected classmates on measures of self-esteem, sociometric status, and insight. Interrelationships among criterion measures also were examined. Referred children had significantly lower self-esteem, peer acceptance, and insight than did the comparison group, even though these variables were modestly intercorrelated. Thus, the study lends support to the trend in prior research associating deficits in such variables with school maladjustment.     

Amid Progress and Wilderness: Early Reception of Georges Hébert’s Naturist Ideas in Brazil During the First Half of the Twentieth Century

Abstract

This paper aims at analyzing how Hébert’s naturist ideas were received and assimilated in Brazil based on the perusal of sources such as Azevedo (1915, 1920, 1931), Miranda (1945) as well as some broadsheets and periodicals, for example Correio da Manhã, O Paiz, Gazeta de Noticias, and Fon-Fon! (1913–1928). Furthermore, it investigates by what means Hébert’s conception of nature integrated the mindset of Brazilian sanitarians in the first half of the twentieth century. Evidence suggests that there must have been some intertwinement of points of view that brought together Hebert’s Natural Method and the French Naturist Perspective at the time of the arrival of the latter in Brazil. Hébert’s thoughts on the concept of Nature reached Brazil early in the 1910s, and were incorporated in the shaping of a new approach to therapeutic treatments focused on preserving the patient’s welfare. As a result, this study has enabled us to properly understand the reception of Hébert’s works in Brazil, and come to terms with the historical connection between French gymnastic practices based on the Natural Method and their subsequent acclimatized Brazilian variants.     

Analysis of elbow muscle strength parameters in Brazilian jiu-jitsu practitioners

Upper-body dynamic and isometric maximum strength are essential components for success in Brazilian jiu-jitsu (BJJ). This study was aimed at analysing strength parameters in the elbow flexor and extensor muscles of BJJ practitioners. Participants (n = 28) performed maximum isometric contractions of elbow flexors and extensors to determine peak torque (PT), rate of force development (RFD), and the torque–angle (T–A) relationship at elbow angles of 45°, 60°, 75°, 90°, 105°, and 120°. Additionally, concentric and eccentric PTs were measured at 1.04 rad·s^-1. Student t-test and ANOVA were performed using α = 0.05. Elbow flexors were stronger isometrically (P < 0.001, ES = 1.23) but weaker concentrically (P < 0.05, ES = 0.54) than extensor muscles, possibly because of the extensive grip disputes and pushing of opponents in BJJ. The T–A relationship had an inverted “U”-shape. Torque differences across elbow angles were moderate (ES = 0.62) for the extensor and large (ES = 0.92) for the flexor muscles. Isometric torque was greatest for elbow angles of 105° and 75° and smallest for 45° and 120° for extensor and flexor muscles, respectively. Elbow flexors had a greater RFD than extensors, regardless of elbow angle. The present study provides comprehensive results for elbow muscle strength in BJJ practitioners.     

Navigating Alarming Media Messages About Nutrition and Health

Science & Education - This study focuses the emerging need for young people to critically respond to alarming messages in contemporary media highlighting the potential benefits or harms of...