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61.
A new method of surface modification is described for enabling the in situ formation of homogenous porous polymer monoliths (PPMs) within poly(dimethylsiloxane) (PDMS) microfluidic channels that uses 365 nm UV illumination for polymerization. Porous polymer monolith formation in PDMS can be challenging because PDMS readily absorbs the monomers and solvents, changing the final monolith morphology, and because PDMS absorbs oxygen, which inhibits free-radical polymerization. The new approach is based on sequentially absorbing a non-hydrogen-abstracting photoinitiator and the monomers methyl methacrylate and ethylene diacrylate within the walls of the microchannel, and then polymerizing the surface treatment polymer within the PDMS, entangled with it but not covalently bound. Four different monolith compositions were tested, all of which yielded monoliths that were securely anchored and could withstand pressures exceeding the bonding strength of PDMS (40 psi) without dislodging. One was a recipe that was optimized to give a larger average pore size, required for low back pressure. This monolith was used to concentrate and subsequently mechanical lyse B lymphocytes. 相似文献
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The aim of this study was to assess the effects of variations in the volume and intensity of resistance training in highly skilled athletes on neural adaptive mechanisms: the maximality and pattern of neural drive. The maximality of muscle activation was measured using a high-resolution sample and hold amplifier to record interpolated twitches. The pattern of neural drive was measured by analysing isometric torque-time curves and electromyographic (EMG) characteristics during the performance of rapid isometric contractions at maximal effort. The volume and intensity of training were varied at 4-weekly intervals to systematically emphasize the development of strength, power and motor performance in 14 highly skilled track and field athletes (e.g. discus, hammer, javelin, shot put and weight). Knee extension strength increased significantly by 15% during steady maximal isometric contractions and by 24% during rapid isometric contractions at maximal effort after the 16-week training programme (P < 0.05). Increases in EMG amplitude and rate of EMG activation indicated that improvements to the pattern of neural drive occurred with sport-specific resistance training (P < 0.05). The maximality and pattern of neural drive did not change in the control group. 相似文献
64.
G. Brian Burke 《中国图书馆学报》2008,34(4)
20世纪90年代中期以后,随着电子政府服务的发展,美国联邦政府一些跨机构工作小组开始致力于政府信息定位服务(GILS)的相关调查研究,并在大量合作项目的基础上构建起联邦政府的GILS框架。此后,美国各州政府和机构也在此基础上探索构建了各具特色的GILS服务。GILS现已逐渐融合到美国电子政府整体建设之中,不仅通过因特网为公民提供政府数字信息,而且还可提供广泛的政府服务。各种类型的GILS服务之间的交流与合作也在积极展开。 相似文献
65.
The development of reasoning skills, higher-level thinking skills, and science process skills are some of the benefits students can realize by participating in inquiry in the science laboratory. We used student responses to the Alternative Assessment of Science Process Skills (AASPS) developed by the Missouri Department of Education and the Department of Educational Assessment to develop the Science Process Skills Inventory (SPSI). The SPSI was then used to analyze student efforts at writing experimental designs. Our goal was to gain insight into factors that may be related to students successfully designing experiments. The instrument guides teachers and researchers in assessing seven main components of experimental designs. Each component consists of elements unique to the specific laboratory exercise. Subsequent to its development, the instrument was used to score 364 student responses to the “design an experiment” portion of an alternative assessment instrument for science process skills. Results indicate that explicit, incremental development of the science process skills of formulating hypotheses and identifying variables, together with model examples, may be a means to facilitate student success in designing science experiments. Implications for the classroom and for research are discussed. © 1996 John Wiley & Sons, Inc. 相似文献
66.
This work is an annotated bibliography that consists of articles, books, conference papers, dissertations, reports, etc. published in various library and information science forums on the subject of librarianship in the Maghreb. The goal of preparing this work is to provide a list of citations with abstracts that librarians, library students, and library scholars can use to perform research within this subject area and further the body of knowledge. The research methodology that was used to find these citations involved searching the database versions of ERIC, Dissertations Abstracts Online, and Library Literature within the online public access catalog of the Auburn University library system. It also involved searching the online databases of Library and Information Science Abstracts (LISA), British Education Index, andEducation Abstracts within the DIALOG database as well as the respective print versions of these resources. While this work is by no means an exhaustive critique of the entire Maghrebi library and information science literature, it does strive to be comprehensive in terms of its country-by-country analysis of librarianship and information science within the region. In providing a citation for a non-English language work, the English equivalent of the title of that work will be given next to the non-English title. 相似文献
67.
Alannah K. A. McKay David B. Pyne Peter Peeling Avish P. Sharma Megan L.R. Ross Louise M. Burke 《Journal of sports sciences》2019,37(5):553-559
Carbohydrate (CHO) availability could alter mucosal immune responses to exercise. This study compared the effect of three dietary approaches to CHO availability on resting and post-exercise s-IgA levels. Elite race walkers (n = 26) adhered to a high CHO diet (HCHO), periodised CHO availability (PCHO) or a low CHO/high fat diet (LCHF) for 3 weeks while completing an intensified training program. HCHO and PCHO groups consumed 8.0–8.5 g.kg?1 CHO daily, with timing of ingestion manipulated to alter CHO availability around key training sessions. The LCHF diet comprised 80% fat and restricted CHO to < 50 g.day?1. A race walk test protocol (19 km females, 25 km males) was completed at baseline, after adaptation, and following CHO restoration. On each occasion, saliva samples were obtained pre- and post-exercise to quantify s-IgA levels. Resting s-IgA secretion rate substantially increased ~ two-fold post-intervention in all groups (HCHO: 2.2 ± 2.2, PCHO: 2.8 ± 3.2, LCHF: 1.6 ± 1.6; fold-change± 95% confidence limits), however, no substantial differences between dietary treatments were evident. Post-exercise, substantial 20–130% increases in s-IgA concentration and 43–64% reductions in flow rate occurred in all dietary treatments, with trivial differences evident between groups. It appears that high volume training overrides any effect of manipulating CHO availability on mucosal immunity in elite athletes. 相似文献
68.
Michael Burke 《Sport in Society》2019,22(3):499-513
Over the past two decades, there have been a number of sociological investigations of participation by women in sports that had previously appeared to have been played exclusively by men. These investigations have rightly celebrated this participation as examples of greater physical empowerment, choice and freedom for women in sport. Several of these investigations have gone further by utilizing McCaughey’s notion of physical feminism to argue that participation in these sports is indicative of a broader feminist political challenge. This paper contends that this characterization of the broader political challenge is a misinterpretation of McCaughey’s physical feminism. Further, this misinterpretation is indicative of the theoretical underpinnings of the shift from a second wave radical feminism to a third wave celebrity feminism. This paper proposes a set of commitments that would be necessary, although not sufficient, to see these women’s leagues as feminist organizations that politically challenge patriarchal power. 相似文献
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Despite the popularity and strong advocacy for combining quantitative and qualitative methods, few mixed methods approaches are found in the sport management research. As a result, this article examines the frequency with which mixed methods research has been used in recent sport management research, and demonstrates ways in which mixed methods can help improve the validity of research findings in sport management related topics. Because research in sport management often is concerned with causal questions, this article provides mixed methods designs for improving causal inference. Examples are provided from three areas of sport management research, including marketing, organizational behavior, and finance. The designs that are provided are based on the mixed methods design dimensions of time order and priority of quantitative and qualitative data. 相似文献