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991.
The ability to think analytically and creatively is crucial for success in the modern workforce, particularly for graduate students, who often aim to become physicians or researchers. Analysis of the primary literature provides an excellent opportunity to practice these skills. We describe a course that includes a structured analysis of four research papers from diverse fields of biology and group exercises in proposing experiments that would follow up on these papers. To facilitate a critical approach to primary literature, we included a paper with questionable data interpretation and two papers investigating the same biological question yet reaching opposite conclusions. We report a significant increase in students’ self-efficacy in analyzing data from research papers, evaluating authors’ conclusions, and designing experiments. Using our science-process skills test, we observe a statistically significant increase in students’ ability to propose an experiment that matches the goal of investigation. We also detect gains in interpretation of controls and quantitative analysis of data. No statistically significant changes were observed in questions that tested the skills of interpretation, inference, and evaluation.  相似文献   
992.
993.
高硬度不锈钢的使用需求在快速增长.尽管析出硬化不锈钢具有高强度,但在粉末冶金(PM)中使用的并不多.可通过加入在时效过程形成金属问沉淀的成份如铜、铌对这些合金进行强化.析出硬化级不锈钢的耐腐蚀性能可与铬镍级(300系列)相媲美.本文提出了两种析出硬化不锈钢粉末的物理性质和微观结构:17-4PH,一种高铬马氏体析出硬化不锈钢,优化条件后应用于粉末冶金中;另一种是在析出反应中使用铜的新型低铬(12w/o)合金.这种新型合金(410LCu)被视为满足高强度和中等耐腐蚀性的要求的低成本选择.  相似文献   
994.
An important part of online courses is the delivery of instruction via video lectures. Video lectures should use media effectively to reduce extraneous load and maximize cognitive processing, thereby helping students to learn. Instructors may be able to reduce extraneous load by varying the number of audio and visual media used. This study presents analysis from a survey of students (n = 1701) enrolled in a cyber university in South Korea to investigate the relationship between media diversity in video lectures and extraneous load. Results showed a negative relationship between media diversity and extraneous load. Students who noted more types of media stated that they experienced less extraneous load. The implications of these results are of use to instructors who want to use diverse media to promote a better understanding of learning material.  相似文献   
995.
Aim: The aim of this study was to examine the relationship between ventilatory adaptation and performance during altitude training at 2700?m. Methods: Seven elite cyclists (age: 21.2?±?1.1?yr, body mass: 69.9?±?5.6?kg, height 176.3?±?4.9?cm) participated in this study. A hypoxic ventilatory response (HVR) test and a submaximal exercise test were performed at sea level prior to the training camp and again after 15 d at altitude (ALT15). Ventilation (VE), end-tidal carbon-dioxide partial pressure (PETCO2) and oxyhaemoglobin saturation via pulse oximetry (SpO2) were measured at rest and during submaximal cycling at 250?W. A hill climb (HC) performance test was conducted at sea level and after 14 d at altitude (ALT14) using a road of similar length (5.5–6?km) and gradient (4.8–5.3%). Power output was measured using SRM cranks. Average HC power at ALT14 was normalised to sea level power (HC%). Multiple regression was used to identify significant predictors of performance at altitude. Results: At ALT15, there was a significant increase in resting VE (10.3?±?1.9 vs. 12.2?±?2.4?L·min?1) and HVR (0.34?±?0.24 vs. 0.71?±?0.49?L·min?1·%?1), while PETCO2 (38.4?±?2.3 vs. 32.1?±?3.3?mmHg) and SpO2 (97.9?±?0.7 vs. 94.0?±?1.7%) were reduced (P?VE at altitude as significant predictors of HC% (adjusted r2?=?0.913; P?=?0.003). Conclusions: Ventilatory acclimatisation occurred during a 2 wk altitude training camp in elite cyclists and a higher HVR was associated with better performance at altitude, relative to sea level. These results suggest that ventilatory acclimatisation is beneficial for cycling performance at altitude.  相似文献   
996.
This study examined the influence of body composition on temperature and blood flow responses to post-exercise cold water immersion (CWI), hot water immersion (HWI) and control (CON). Twenty-seven male participants were stratified into three groups: 1) low mass and low fat (LM-LF); 2) high mass and low fat (HM-LF); or 3) high mass and high fat (HM-HF). Experimental trials involved a standardised bout of cycling, maintained until core temperature reached 38.5°C. Participants subsequently completed one of three 15-min recovery interventions (CWI, HWI, or CON). Core, skin and muscle temperatures, and limb blood flow were recorded at baseline, post-exercise, and every 30 min following recovery for 240 min. During CON and HWI there were no differences in core or muscle temperature between body composition groups. The rate of fall in core temperature following CWI was greater in the LM-LF (0.03 ± 0.01°C/min) group compared to the HM-HF (0.01 ± 0.001°C/min) group (P = 0.002). Muscle temperature decreased to a greater extent during CWI in the LM-LF and HM-LF groups (8.6 ± 3.0°C) compared with HM-HF (5.1 ± 2.0°C, P < 0.05). Blood flow responses did not differ between groups. Differences in body composition alter the thermal response to post-exercise CWI, which may explain some of the variance in the responses to CWI recovery.  相似文献   
997.
This paper reports data from the evaluation of a coach education programme provided by a major national governing body of sport (NGB) in the UK. The programme was designed for youth sport coaches based on research evidence that suggests that CPD is most effective in supporting practitioner learning when it is interactive, collaborative and located in practice. At the same time, the NGB was keen to ensure that in order to meet the objectives of the organisation, there was some consistency in delivery across the various practice sites. The research aimed to investigate how the original CPD programme was enacted across eight professional sports clubs, and to understand how professional knowledge was interpreted and negotiated between participants at the NGB and sports club levels. Over a 2-year period, data were collected from a series of focus groups and extended individual semi-structured interviews. Participants were 7 senior managers, 8 coach educators, 8 Academy club directors and 12 sports club coaches. Data were initially analysed inductively and, drawing on the theoretical work of Bernstein [(1999). Vertical and horizontal discourse: An essay. British Journal of Sociology of Education, 20(2), 157–173, (2000). Pedagogy, symbolic control and identity: Theory, research, critique (Rev. ed.). Lanham, MD: Rowman & Littlefield], illustrate the numerous ways in which programme knowledge was interpreted, facilitated and blocked at different levels of the organisation. The paper adds new insights into the complexities of coach education settings and the inherent challenges faced when attempting to ‘roll out’ a coach education intervention – even when it is ‘evidence-based’.  相似文献   
998.
It is believed that increasing the X-factor (movement of the shoulders relative to the hips) during the golf swing can increase ball velocity at impact. Increasing the X-factor may also increase the risk of low back pain. The aim of this study was to provide recommendations for the three-dimensional (3D) measurement of the X-factor and lower trunk movement during the golf swing. This three-part validation study involved; (1) developing and validating models and related algorithms (2) comparing 3D data obtained during static positions representative of the golf swing to visual estimates and (3) comparing 3D data obtained during dynamic golf swings to images gained from high-speed video. Of particular interest were issues related to sequence dependency. After models and algorithms were validated, results from parts two and three of the study supported the conclusion that a lateral bending/flexion-extension/axial rotation (ZYX) order of rotation was deemed to be the most suitable Cardanic sequence to use in the assessment of the X-factor and lower trunk movement in the golf swing. The findings of this study have relevance for further research examining the X-factor its relationship to club head speed and lower trunk movement and low back pain in golf.  相似文献   
999.
This experiment examined the applicability of the generalized matching law to changes in divided-attention performance produced by variations in relative reinforcement rate. Pigeons were exposed to a delayed matching-to-sample procedure in which compound samples (color 1 line orientation) and element comparisons (two colors or two line orientations) were used. The relative rate of reinforcement for accurate matches on the two types of comparison trials was varied. Variations in relative accuracy with changes in relative reinforcement were well described by the generalized matching law. We suggest that the bias and sensitivity parameters of the generalized matching law may measure the contributions of sensory activation and stimulus pertinence, respectively, to divided-attention performance. Additional work using similar analyses might contribute to a more general quantitative account of how differential consequences contribute to decision processes involved in the allocation of attention.  相似文献   
1000.
Altitude exposure and exercise elicit oxidative stress in blood; however, exercise recovery at 5000 m attenuates oxidative stress. The purpose was to determine the altitude threshold at which blood oxidative stress is blunted during exercise recovery. Twelve males 18–28 years performed four-cycle ergometry bouts (60 min, 70% VO2max, at 975 m). In a randomised counterbalanced crossover design, participants recovered 6 h at 0, 1667, 3333 and 5000 m in a normobaric hypoxia chamber (recovery altitudes were simulated by using a computerised system in an environmental chamber by lowering the partial pressure of oxygen to match that of the respective altitude). Oxygen saturation was monitored throughout exercise recovery. Blood samples obtained pre-, post-, 1 h post- and 5 h post-exercise were assayed for ferric-reducing antioxidant plasma, Trolox equivalent antioxidant capacity, uric acid, lipid hydroperoxides and protein carbonyls. Muscle biopsies obtained pre and 6 h were analysed by real-time polymerase chain reaction to quantify expression of hemeoxgenase 1, superoxide dismutase 2 and nuclear factor (euthyroid-derived 2)-like factor. Pulse oximetry data were similar during exercise, but decreased for the three highest recovery elevations (0 m = 0%, 1667 m = ?3%; 3333 m = ?7%; 5000 m = ?17%). A time-dependent oxidative stress occurred following exercise for all variables, but the two highest recovery altitudes partially attenuated the lipid hydroperoxide response (0 m = +135%, 1667 m = +251%, 3333 m = +99%; 5000 m = +108%). Data may indicate an altitude threshold between 1667 and 3333 m, above which the oxidative stress response is blunted during exercise recovery.  相似文献   
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