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It is known that an increased level of red blood cell 2,3-diphosphoglycerate (DPG) shifts the oxyhemoglobin dissociation curve to the right, thus allowing a greater unloading of oxygen at the tissue level. It has been hypothesized that phosphate might help increase VO2max by increasing 2,3-DPG level. Eight trained cyclists underwent three cycle ergometer tests (control, placebo, and experimental) to determine whether phosphate ingestion had any positive effect on VO2max, time to exhaustion, serum 2,3-DPG, and serum phosphate levels. We found no change between the control, placebo, or experimental conditions in pretest serum phosphate levels, but we did find increases in 2,3-DPG levels in the phosphate condition (p less than .05), which suggests that even a small amount of phosphate could increase levels of 2,3-DPG. We also found significant differences in VO2max between the control (p less than .05) and placebo (p less than .02) conditions and also in time to exhaustion between the three conditions (p less than .05). We suggest that phosphate may have an ergogenic effect, but clearly more work needs to be undertaken to ascertain the amount of phosphate required and the magnitude of the effect.  相似文献   
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The purpose of this study was to determine the differences between third and sixth grade female and male students when retelling orally a story read silently. The students' retelling of the story was analyzed by comparing how closely, both structurally and linguistically, they paralleled the T-units or communication units of the author. In general, female students performed significantly differently than did male students. The researchers examine these differences in light of recent research in the area of gender differences.  相似文献   
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This article examines some of the contextual factors underlying the move from teaching to learning in universities over the next two decades. It considers the major characteristics of and elements in emerging learning processes. It assesses the likely impact of the above on personnel policy and practice in universities and suggests some broader organizational issues for universities as a consequence of the analysis. The article draws on research conducted by the author for two recent international studies, sponsored by the Association of European Universities and UNESCO, and on perspectives derived from various strategic evaluation exercises undertaken under the auspices of CRE.  相似文献   
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This study examined how and why dopamine transporter (DAT1) susceptibility alleles moderate the relation between maternal unresponsiveness and young children's behavior problems in a disadvantaged, predominantly minority sample of 201 two‐year‐old children and their mothers. Using a multimethod, multisource design, the findings indicated that a genetic composite of DAT1 susceptibility alleles (rs27072, rs40184) potentiated associations between maternal unresponsive caregiving and increases in children's behavior problems 2 years later. Moderator‐mediated‐moderation analyses further revealed that the DAT1 diathesis was more proximally mediated by the potentiating effects of children's uninhibited temperament in the pathway between maternal unresponsiveness and disruptive behavior problems. Results are interpreted in the context of supporting and advancing the biosocial developmental model (Beauchaine & Gatzke‐Kopp, 2012).  相似文献   
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Changes to special educational needs and disability (SEND) legislation in England were implemented in 2014. Here, we evaluate the impact of these changes from the perspective of 80 autistic young people aged 16–25 years. Using an online survey and/or interviews, we examined young people’s views on three key principles of the SEND reforms: the help and support provided to them; whether they were given a say in the choices and support that they were offered; and their satisfaction with their educational journeys and outcomes. The results paint a mixed picture. Our sample of young people reported varied experiences regarding the help and support they received, and how much of a say they had regarding the choices and support available to them. The types of schooling they accessed played a role here: young people in mainstream schools highlighted particular challenges in accessing appropriate support, while many young people in special schools said they felt well supported. Parental advocacy was crucial for all young people, as was having key ‘champions’ in the form of teachers who really knew them well. The need for the development of general life and self-advocacy skills was apparent, however, especially in preparing the young people for life after school. Encouragingly, most of our participants were generally happy with their current situation, despite identifying several areas for further improvement. Overall, the results highlight the importance of listening to—and learning from—autistic young people, throughout their educational journeys and especially as they transition to adulthood.  相似文献   
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The study examined the moderating role of children's affect-biased attention to angry, fearful, and sad adult faces in the link between interparental conflict and children's distinct forms of involvement. Participants included 243 preschool children (Mage = 4.60 years, 56% female) and their parents from racially (48% African American, 43% White) and socioeconomically (median annual household income = $36,000) diverse backgrounds. Data collection took place in the Northeastern United States (2010–2014). Utilizing a multi-method, multi-informant, longitudinal design, attention away from anger selectively amplified the link between interparental conflict and children's subsequent coercive involvement (β = −.15). Greater attention to fear potentiated the pathway between interparental conflict and children's later cautious (β = .14) and caregiving involvement (β = .15). Findings are interpreted in the context of environmental sensitivity models.  相似文献   
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