An integrated teaching method of gross anatomy and computed tomography radiology

It is essential for medical students to learn and comprehend human anatomy in three dimensions (3D). With this in mind, a new system was designed in order to integrate anatomical dissections with diagnostic computed tomography (CT) radiology. Cadavers were scanned by CT scanners, and students then consulted the postmortem CT images during cadaver dissection to gain a better understanding of 3D human anatomy and diagnostic radiology. Students used handheld digital imaging and communications in medicine viewers at the bench‐side (OsiriX on iPod touch or iPad), which enabled “pixel‐to‐tissue” direct comparisons of CT images and cadavers. Students had lectures and workshops on diagnostic radiology, and they completed study assignments where they discussed findings in the anatomy laboratory compared with CT radiology findings. This teaching method for gross and radiological anatomy was used beginning in 2009, and it yielded strongly positive student perspectives and significant improvements in radiology skills in later clinical courses. Anat Sci Educ 7: 438–449. © 2014 American Association of Anatomists.     

科技创新团队成员建设性冲突管理

在产品开发和技术创新过程中,科技创新团队成员的建设性冲突主要包括任务冲突和过程冲突,这两类冲突均对创新价值链上的各项创新工作具有促进效应.构建模型,阐述科技创新团队成员的建设性冲突对科技创新价值链上的技术创新、产品创新、管理模式创新的促进关系,实证科技创新团队成员的建设性冲突对组织的技术创新及其管理模式创新具有显著正向...     

科技创新团队基于价值链的创新绩效管理

通过访谈法和问卷调查法可知,在科技创新团队创新绩效管理中,创新绩效考评往往侧重于创新结果绩效而忽略创新过程绩效,从而导致科技创新团队缺乏创新积极性.对此,从同时注重创新过程绩效与创新成果绩效的视角,分析和探讨科技创新团队基于价值链的创新绩效评价模式.在对创新价值链构成分析基础上,采用层次分析法从创新知识获取过程和创新产...     

Contraction and extension of Vorticella and its mechanical characterization under flow loading

We have studied the contraction and extension of Vorticella convallaria and its mechanical properties with a microfluidic loading system. Cells of V. convallaria were injected to a microfluidic channel (500 μm in width and 100 μm in height) and loaded by flow up to ∼350 mm s⁻¹. The flow produced a drag force on the order of nanonewton on a typical vorticellid cell body. We gradually increased the loading force on the same V. convallaria specimen and examined its mechanical property and stalk motion of V. convallaria. With greater drag forces, the contraction distance linearly decreased; the contracted length was close to around 90% of the stretched length. We estimated the drag force on Vorticella in the channel by calculating the force on a sphere in a linear shear flow.     

Learning to Teach Science: The Curriculum of Student Teaching in Hiroshima "Attached" Schools

Journal of Science Teacher Education -     

A method of extracting malicious expressions in bulletin board systems by using context analysis

Bulletin board systems are well-known basic services on the Internet for information frequent exchange. The convenience of bulletin boards enables us to communicate with other persons and to read the communication contents at any time. However, malicious postings about crimes are serious problems for serving companies and users. The extracting scheme of the traditional methods depends on words or a sequence of words without considering contexts of articles and, therefore, it takes a lot of human efforts to alert malicious articles. In order to reduce the human efforts, this paper presents a new filtering algorithm that can recover the error rate of false positive for non-malicious articles by using context analysis. The presented scheme builds detecting knowledge by introducing multi-attribute rules. By the experimental results for 11,019 test data, it turns out that sensitivity and specificity of the presented method become 38.7 and 24.1 (%) points higher than traditional method, respectively.     

Bile canaliculi formation by aligning rat primary hepatocytes in a microfluidic device

In this study, we propose a microfluidic cell culture device mimicking the microscopic structure in liver tissue called hepatic cords. The cell culture area of the device was designed to align hepatocytes in two lines in a similar way to hepatic cords. Thanks to the structural design together with a cell seeding procedure, rat primary hepatocytes were successfully aligned in two lines and cultured under perfusion condition. It is shown that aligned hepatocytes gradually self-organize and form bile canaliculi along the hepatic cord-like structure. The present technique to culture hepatocytes with functional bile canaliculi could be used as an alternative to animal testing in the field of drug discovery and toxicological studies, and also be beneficial to tissue engineering applications.     

Rapid microfluidic immunoassay for surveillance and diagnosis of Cryptosporidium infection in human immunodeficiency virus-infected patients

Cryptosporidiosis has been reported to be associated with HIV/acquired immune deficiency syndrome, which greatly reduces the quality of life and shortens the life expectancy of HIV-infected patients. In order to properly treat the infected patients, accurate and automatic diagnostic tools need to be developed. In this study, a novel microfluidic immunochip system was presented for the surveillance and the rapid detection of Cryptosporidium infection in 190 HIV-infected patients from Guangxi, China, using the P23 antigen of Cryptosporidium. The procedure of detection can be completed within 10 min with 2 μl sample consumption. The system also was evaluated using the standard ELISA method. Among 190 HIV-infected individuals, the rate of P23 positivity was 13.7%. Seropositivity in HIV-infected individuals was higher in female patients. The seropositivity to P23 was higher in HIV-infected individuals with high viral load, although the difference was statistically insignificant. Significantly higher Cryptosporidium seropositivity was observed in HIV-infected individuals with a CD4⁺ T-cell count of <200 cells/μl than in those with ≥200 cells/μl. Our results also demonstrate that a lower CD4⁺ T-cell count may reflect an increased accumulated risk for cryptosporidiosis. The detection system was further validated using the standard ELISA method and good correlation between the two methods was found (r = 0.80). Under the same sensitivity, this new microfluidic chip device had a specificity of 98.2%. This developed system may provide a powerful platform for the fast screening of Cryptospordium infection in HIV-infected patients.     

Movements with greater trunk accelerations and their properties during badminton games

Abstract

This study aimed to elucidate the movements requiring greater trunk accelerations and its frequencies during badminton games, and compare the acceleration components among such movements. Trunk acceleration was measured using a triaxial accelerometer during badminton games. The moments that generated >4 G resultant acceleration were extracted, and movements consistent with the extracted moments were identified. We calculated the extracted movement ratio and frequency and compared the resultant, mediolateral, vertical and anteroposterior accelerations between the top five extracted movements. There were 1,342 movements that generated >4 G [mean, 7.72 (95% confidence interval, 7.31–8.14) cases/min]. The top five movements were lunging during underhand strokes with the dominant hand side leg, landing after overhand strokes on the dominant and non-dominant hand side leg, and cutting from a split step using the dominant and non-dominant hand side leg. Landing on the dominant hand side leg had a greater resultant acceleration than the other movements and had the greatest impact during the badminton game. Lunging during underhand strokes on the dominant hand side leg had greater mediolateral acceleration than the other movements. These results reflected the properties of badminton.