Russian Science Citation Index: Areas for Development Identified by Active Users

The current state of the Russian Science Citation Index is analyzed. Several areas for its further development identified by long-standing active users, such as data searching, refinement, and storage; current user alerts; data input with the Science Index license; patent information; and the application programming interface (API) are investigated.     

新课程下对教学反思行为的思考

通过对教学理念、教材、教学方法、学生反馈等方面反思,来促进教学实践合理化和教学观念的更新、教师自身专业素质的提升,推动教学研究深入.     

民国学人专题数据库构建及其学术特征分析——学术共同体视角

[目的/意义]民国时期是中国历史上少有的学术发展活跃期,现阶段有不少民国文献数据库,但都是些面向主题的专题库,而民国学人专题数据库是把基于领域面向主题的数据库升级为以人作为维度的专题数据库,体现出学术交流的特点。[方法/过程]从数据库整体框架、功能设计与实现方面介绍民国学人专题数据库,依托民国学人专题数据库,依次从学者组织机构、学术成果合著与引证行为等多维度揭示民国时期学术共同体的特点,最后引入时序分析方法,探究学者的科研行为随时间的变化特点。[结果/结论]实证表明,民国时期的学术共同体的变迁受外部政治氛围和内部组织流变影响,而通过对引入时序的学者合著与引证关系的梳理,发现学者对民国时期的学术研究热情持续增进,另外民国期间的学者倾向独立创作,民国之后的学者的合著行为才逐渐频繁。     

构建开放教育中《计算机应用基础》课程的学习支持服务体系

远程开放教育就是以学生为中心的全方位的助学服务;远程开放教育的教的过程就是为学生提供全方位学习支持服务的过程,而学的过程就是学生使用、接受服务的过程,做好学习支持服务是确保开放教育顺利进行的保证。本文主要从《计算机应用基础》课程的导学过程来说明是如何为开放教育学员提供完善的支持服务的。     

专利竞争力评估系统设计与高价值专利识别

以快速、有效识别高质量专利为目标,设计一种专利竞争力评估软件系统,由数据库、指标体系、用户管理和可视化等功能模块构成,可实现千件级专利数据的快速导入、评分和可视化结果导出.利用自建航空专利数据库和外部专利数据进行实例验证,评估结果和可视化分析表明,金奖专利、高转化价值专利得分最高,专利布局更加合理.最后,结合内外部性能...     

Thermophysical properties of the regolith on the lunar far side revealed by the in situ temperature probing of the Chang’E-4 mission

Temperature probes onboard the Chang’E-4 (CE-4) spacecraft provide the first in situ regolith temperature measurements from the far side of the Moon. We present these temperature measurements with a customized thermal model and reveal the particle size of the lunar regolith at the CE-4 landing site to be ∼15 μm on average over depth, which indicates an immature regolith below the surface. In addition, the conductive component of thermal conductivity is measured as ∼1.53 × 10^–3 W m^–1 K^–1 on the surface and ∼8.48 × 10^–3 W m^–1 K^–1 at a depth of 1 m. The average bulk density is ∼471 kg m^–3 on the surface and ∼824 kg m^–3 in the upper 30 cm of the lunar regolith. These thermophysical properties provide important additional ‘ground truth’ at the lunar far side, which is critical for the future analysis and interpretation of global temperature observations.     

Cyclic-anion salt for high-voltage stable potassium-metal batteries

Electrolyte anions are critical for achieving high-voltage stable potassium-metal batteries (PMBs). However, the common anions cannot simultaneously prevent the formation of ‘dead K’ and the corrosion of Al current collector, resulting in poor cycling stability. Here, we demonstrate cyclic anion of hexafluoropropane-1,3-disulfonimide-based electrolytes that can mitigate the ‘dead K’ and remarkably enhance the high-voltage stability of PMBs. Particularly, even using low salt concentration (0.8 M) and additive-free carbonate-based electrolytes, the PMBs with a high-voltage polyanion cathode (4.4 V) also exhibit excellent cycling stability of 200 cycles with a good capacity retention of 83%. This noticeable electrochemical performance is due to the highly efficient passivation ability of the cyclic anions on both anode and cathode surfaces. This cyclic-anion-based electrolyte design strategy is also suitable for lithium and sodium-metal battery technologies.     

Combination of Se-methylselenocysteine,D-α-tocopheryl succinate, β-carotene,and L-lysine can prevent cancer metastases using as an adjuvant therapy

ObjectivePrimary tumor treatment through surgical resection and adjuvant therapy has been extensively studied, but there is a lack of effective strategies and drugs for the treatment of tumor metastases. Here, we describe a functional product based on a combination of compounds, which can be used as an adjuvant therapy and has well-known mechanisms for inhibiting cancer metastases, improving anti-cancer treatment, and enhancing immunity and antioxidant capacity. Our designed combination, named MVBL, consists of four inexpensive compounds: L-selenium-methylselenocysteine (MSC), D-‍α‍-tocopheryl succinic acid (VES), β‍-carotene (β‍-Ca), and L-lysine (Lys).MethodsThe effects of MVBL on cell viability, cell cycle, cell apoptosis, cell migration, cell invasion, reactive oxygen species (ROS), and paclitaxel (PTX)-combined treatment were studied in vitro. The inhibition of tumor metastasis, antioxidation, and immune enhancement capacity of MVBL were determined in vivo.ResultsMVBL exhibited higher toxicity to tumor cells than to normal cells. It did not significantly affect the cell cycle of cancer cells, but increased their apoptosis. Wound healing, adhesion, and transwell assays showed that MVBL significantly inhibited tumor cell migration, adhesion, and invasion. MVBL sensitized MDA-MB-231 breast cancer cells to PTX, indicating that it can be used as an adjuvant to enhance the therapeutic effect of chemotherapy drugs. In mice, experimental data showed that MVBL inhibited tumor metastasis, prolonged their survival time, and enhanced their antioxidant capacity and immune function.ConclusionsThis study revealed the roles of MVBL in improving immunity and antioxidation, preventing tumor growth, and inhibiting metastasis in vitro and in vivo. MVBL may be used as an adjuvant drug in cancer therapy for improving the survival and quality of life of cancer patients.     

基于嵌入式Linux的网络传输系统的内核编译与移植

以Xscale处理器架构的PXA255开发板为硬件基础,将开发好的嵌入式TCP/IP协议栈加载到嵌入式Linux构成的嵌入式系统内核中,设计并构成了基本的硬件、软件平台,在此基础上按照内核重编译的工作流程和要求,完成了TCP/IP协议栈在嵌入式Linux操作系统2.6.10内核中的加载与编译,并最终移植到Xscale处理器架构的PXA255开发板上。