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161.
This paper presents a quick, easy to implement and versatile way of using stochastic simulations to investigate the power and design of using single nucleotide polymorphism (SNP) arrays for genome-wide association studies in farm animals. It illustrates the methodology by discussing a small example where 6 experimental designs are considered to analyse the same resource consisting of 6006 animals with pedigree and phenotypic records: (1) genotyping the 30 most widely used sires in the population and all of their progeny (515 animals in total), (2) genotyping the 100 most widely used sires in the population and all of their progeny (1 102 animals in total), genotyping respectively (3) 515 and (4) 1 102 animals selected randomly or genotyping respectively (5) 515 and (6) 1 102 animals from the tails of the phenotypic distribution. Given the resource at hand, designs where the extreme animals are genotyped perform the best, followed by designs selecting animals at random. Designs where sires and their progeny are genotyped perform the worst, as even genotyping the 100 most widely used sires and their progeny is not as powerful of genotyping 515 extreme animals. 相似文献
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Ken E. Blaiklock 《Journal of Research in Reading》2004,27(1):36-57
Previous correlational and experimental research has found a positive association between phonological awareness and reading skills. This paper provides an overview of studies in this area and shows that many studies have neglected to control for extraneous variables such as ability, phonological memory, pre‐existing reading skills and letter knowledge. The paper reports on the results of a longitudinal study that took account of these variables when examining the relationship between phonological awareness and reading for a group of children during their first two years at school. Children showed rhyme awareness before they began to read but were unable to perform a phoneme deletion task until after they had developed word‐reading skills. Concurrent and predictive correlations between phonological awareness scores and later reading were often significant and remained so after adjusting for verbal ability or phonological memory. Controlling for letter knowledge, however, reduced most correlations to nonsignificant levels. 相似文献
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ABSTRACT We report on three projects and an accompanying critical research agenda designed to establish and evaluate a new pedagogy in Australian physical education based on the sport education curriculum model first published by Siedentop et al. [Siedentop, D., Mand, C. & Taggart, A. (1986) Physical Education: Teaching and Curriculum Strategies for Grades 5‐12 (Palo Alto, Mayfield]. The projects, involving over 80 schools throughout Australia, are set in a context featuring an amalgam of postmodern youth culture, governmental inquiries and reports and the continuing difficulties facing physical educators in their workplaces. Against a backdrop of subject marginatyia, the projects’ findings have lent support to the proposition that it is dysfunctional programme structures (rather that deficits in teaching skills) that are most to blame in denying teachers access to significant subject matter learning targets. Our work presents evidence that the student‐centred, extended‐unit sport education curriculum model has the potential to be responsive to these challenges. It is conducive to ongoing school‐based professional and curriculum development, has led to widespread programme restructuring, has improved outcomes for many lower skilled students and has generally produced positive results for aspects of students’ social development. However girls tend still to be dominated by boys in particular sports. The model is positively affecting the career expectations of pre‐service students. As the model is already diffusing rapidly in Australian schools, there is a need to identify issues and chart an educational course for any further development. 相似文献
166.
A feature of academic literature on physical education teacher education (PETE) is the expectation that it can and should impact upon student teachers' beliefs and prospective practices in some significant ways. This is despite research over the last 20 years or more alluding to the apparent failure of PETE to ‘shake or stir’ (Evans et al., 1996) what might be termed the (typically conservative and conventional) pre-dispositions of student and early career PE teachers. In this article, we examine the perceptions of PE student teachers in Norway in order to ascertain just what it is that makes them so resistant to change and, for that matter, such infertile ground for sowing the seeds of reflexivity. The study involved semi-structured interviews with 41 PE student teachers from the three routes through teacher education available at Nord University College (Nord UC). Among the main themes identified in the data were the PE students' perceptions of: the purposes (and ostensible benefits) of school PE and PETE as well as the nature of PETE itself (including subsidiary themes of sporting and teaching skills, other ‘competencies’, school placements, mentoring and mentors, PETEs' (physical education teacher educators) teaching styles and the students teachers' relationships with the PETEs). The article concludes that, as far as the students at Nord UC were concerned, the significance of PETE revolved around the programme's efficacy in developing the sporting skills and teaching techniques they viewed as central to their preparation for teaching. The minimal impact of the more theoretical aspects of PETE appeared to be partly attributable to the students' perceptions of PE as synonymous with sport in schools and partly to their particularly pragmatic orientations towards PETE. In this vein, the students viewed experience as the most important, most legitimate ‘evidence’ on which to base their beliefs and practices and were resistant to the ‘theory’ of teacher education, rationalising their tendencies to select the evidence that suited them. 相似文献
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Early Differentiation of Causal Mechanisms Appropriate to Biological and Nonbiological Kinds 总被引:2,自引:0,他引:2
Although Piaget characterized young children as precausal until about 7-8 years of age, recent work indicates that preschoolers do honor fundamental principles of causality. This literature has mainly focused on general principles invoked in reasoning about mechanical events. By contrast, the present study examined whether children differentiate between the causal mechanisms appropriate for different conceptual domains. The results of 3 preliminary investigations and 1 main experiment suggested that preschoolers prefer natural mechanisms for color inheritance in biological kinds, particularly when causal substrates resemble their consequences. By contrast, the same children recognized the importance of human intentions in producing the color of an artifact, and also judged that mechanical mechanisms serve to mediate between intentions and outcomes. The results are relevant to recent studies on the development of biological thought, and overall suggest that early causal reasoning reflects both domain-specific and domain-general principles. 相似文献