A validated search assessment tool: assessing practice-based learning and improvement in a residency program

Objective:

The objective of this study was to validate an assessment instrument for MEDLINE search strategies at an academic medical center.

Method:

Two approaches were used to investigate if the search assessment tool could capture performance differences in search strategy construction. First, data from an evaluation of MEDLINE searches from a pediatric resident''s longitudinal assessment were investigated. Second, a cross-section of search strategies from residents in one incoming class was compared with strategies of residents graduating a year later. MEDLINE search strategies formulated by faculty who had been identified as having search expertise were used as a gold standard comparison. Participants were presented with a clinical scenario and asked to identify the search question and conduct a MEDLINE search. Two librarians rated the blinded search strategies.

Results:

Search strategy scores were significantly higher for residents who received training than the comparison group with no training. There was no significant difference in search strategy scores between senior residents who received training and faculty experts.

Conclusion:

The results provide evidence for the validity of the instrument to evaluate MEDLINE search strategies. This assessment tool can measure improvements in information-seeking skills and provide data to fulfill Accreditation Council for Graduate Medical Education competencies.

Highlights

• The University of Michigan MEDLINE Search Assessment tool can be used to assess search skills in residency education.
• Five elements were identified as critical elements in the development of an effective MEDLINE search strategy: inclusion of all search concepts, appropriate use of Medical Subject Headings, appropriate use of search limits, successful combination of all concepts, and search efficiency.

Implications

• This validated assessment tool can serve as an effective means to measure improvements in residents'' information-seeking skills and provide data to fulfill Accreditation Council for Graduate Medical Education competencies.

     

刍议EVA指导下采购管理中的增值环节

旨在探索一种新的采购管理模式,帮助企业降低采购成本,提高采购效率。通过构建以EVA为指导的采购流程,重点讨论与采购人员、供应商相关的核心环节,提出了完善采购人员管理体系、健全供应商管理机制等方面的策略,以实现“采购使企业增值”的目的。     

我国高校“去行政化”分析与对策

我国高校的行政化管理模式由来已久,随着现代高等教育体制与教学制度的不断完善,高校行政化收到了越来越多的非议,并逐步演变成为教育体制改革的焦点。通过对高校“行政化”弊端的分析,认真反思如何使高效发展走出“行政化”制约,如何归还高校办学的独立自主权利。由此可见,废除高校行政级别、剥离教育部对高校的管理和评价权、排除行政干预对学术活动带来影响等呼声日益高涨,逐步演变成为“去行政化”改革的重要手段。     

Pheromone synthesis in a biomicroreactor coated with anti-adsorption polyelectrolyte multilayer

To prepare a biosynthetic module in an infochemical communication project, we designed a silicon/glass microreactor with anti-adsorption polyelectrolyte multilayer coating and immobilized alcohol acetyl transferase (atf), one of the key biosynthetic enzymes of the pheromone of Spodoptera littoralis, on agarose beads inside. The system reproduces the last step of the biosynthesis in which the precursor diene alcohol (Z,E)-9,11-tetradecadienol is transformed into the major component (Z,E)-9,11-tetradecadienyl acetate. The scope of this study was to analyze and implement a multilayer, anti-adsorption coating based on layer-by-layer deposition of polyethylenimine/dextransulfate sodium salt (PEI/DSS). The multilayers were composed of two PEI with molecular weights 750 and 1.2 kDa at pH 9.2 or 6.0. Growth, morphology, and stability of the layers were analyzed by ellipsometry and atomic force microscopy (AFM). The anti-adsorption functionality of the multilayer inside the microreactor was validated. The activity of His(6)-(atf) was measured by gas chromatography coupled to mass spectrometer (GC-MS).     

A parallel microfluidic channel fixture fabricated using laser ablated plastic laminates for electrochemical and chemiluminescent biodetection of DNA

Herein is described the fabrication and use of a plastic multilayer 3-channel microfluidic fixture. Multilayer devices were produced by laser machining of plastic polymethylmethacrylate and polyethyleneterapthalate laminates by ablation. The fixture consisted of an array of nine individually addressable gold or gold/ITO working electrodes, and a resistive platinum heating element. Laser machining of both the fluidic pathways in the plastic laminates, and the stencil masks used for thermal evaporation to form electrode regions on the plastic laminates, enabled rapid and inexpensive implementation of design changes. Electrochemiluminescence reactions in the fixture were achieved and monitored through ITO electrodes. Electroaddressable aryl diazonium chemistry was employed to selectively pattern gold electrodes for electrochemical multianalyte DNA detection from double stranded DNA (dsDNA) samples. Electrochemical detection of dsDNA was achieved by melting of dsDNA molecules in solution with the integrated heater, allowing detection of DNA sequences specific to breast and colorectal cancers with a non-specific binding control. Following detection, the array surface could be renewed via high temperature (95 °C) stripping using the integrated heating element. This versatile and simple method for prototyping devices shows potential for further development of highly integrated, multi-functional bioanalytical devices.     

Integrated carbon fiber electrodes within hollow polymer microneedles for transdermal electrochemical sensing

In this study, carbon fiber electrodes were incorporated within a hollow microneedle array, which was fabricated using a digital micromirror device-based stereolithography instrument. Cell proliferation on the acrylate-based polymer used in microneedle fabrication was examined with human dermal fibroblasts and neonatal human epidermal keratinocytes. Studies involving full-thickness cadaveric porcine skin and trypan blue dye demonstrated that the hollow microneedles remained intact after puncturing the outermost layer of cadaveric porcine skin. The carbon fibers underwent chemical modification in order to enable detection of hydrogen peroxide and ascorbic acid; electrochemical measurements were demonstrated using integrated electrode-hollow microneedle devices.     

Individualism-collectivism among Americans, Turks and Turkish immigrants to the U.S.

Whether immigrants to the U.S. from collectivist cultures will adopt American individualist values is an important question at the intersection of theories on acculturation and individualism/collectivism. According to the assimilation hypothesis, Turkish immigrants to the U.S. should become more individualistic with increasing length of stay. Alternatively, the immigrant interdependence hypothesis proposes that the exigencies of immigration require retaining or increasing collectivist values and behaviors, especially the willingness to rely on others. Measures of individualism and collectivism were obtained from Turkish immigrants to the U.S., Turks residing in Istanbul, and residents of Boston. Bostonians and Istanbul residents differed primarily on vertical collectivism, which is the tendency to subordinate ones own goals to those of in-group authority figures. Immigrants’ values did not change with increasing length of stay in the U.S., refuting the assimilation hypothesis. When immigrants were compared to non-immigrants, immigrants endorsed stronger horizontal and vertical collectivism and more desire to both give and receive, consistent with the immigrant interdependence hypothesis. However, this hypothesis was not uniformly supported. Compared to non-immigrants, immigrants reported more self-reliance with competition, and more internal locus of control, indicating a sense of agency and responsibility. Findings are consistent with the view that immigrants adjust in complex ways to their new society, and may have different temperaments than non-immigrants.     

Internal and external focus of attention in a novice form sport

In the current experiment, we examined optimal focus for novices during a movement sequence in which performance was measured on accurate movement form/technique. A novel gymnastics routine was practiced under either an internal skill-relevant, internal skill-irrelevant, external, or no attention focus. Retention and transfer tests were then completed. During acquisition, adopting an internal irrelevant focus significantly improved performance, whereas an external focus degraded performance. There were no significant group differences in the retention and transfer tests. This suggests that learning of movement form/technique did not benefit from a specific focus of attention. The results are interpreted via an attentional capacity viewpoint and the notion that form tasks do not always contain obvious movement effects central to common coding and the constrained action hypothesis.